[Term]
id: PR:000050890
name: D-glucuronyl C5-epimerase O-glycosylated 1 (human)
def: "A D-glucuronyl C5-epimerase (human) that has been O-glycosylated at the residue equivalent to Ser-59 of the amino acid sequence represented by UniProtKB:O94923-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:O94923-1, Ser-59, MOD:00002~GNO:G43417UB." [GlyGen:O94923-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hGLCE/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O94923-1, Ser-59, MOD:00002~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:O94923 ! D-glucuronyl C5-epimerase (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O94923
name: D-glucuronyl C5-epimerase (human)
def: "A D-glucuronyl C5-epimerase that is encoded in the genome of human." [PRO:DNx, UniProtKB:O94923]
comment: Category=organism-gene.
synonym: "GLCE" RELATED Gene-based [UniProtKB:O94923]
synonym: "hGLCE" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0836" RELATED Gene-based [UniProtKB:O94923]
synonym: "hsepi (human)" EXACT [UniProtKB:O94923]
synonym: "heparan sulfate C5-epimerase (human)" EXACT [UniProtKB:O94923]
synonym: "heparosan-N-sulfate-glucuronate 5-epimerase (human)" EXACT [UniProtKB:O94923]
synonym: "heparin/heparan sulfate:glucuronic acid C5-epimerase (human)" EXACT [UniProtKB:O94923]
xref: Reactome:R-HSA-2024106 "PR:O94923 located_in GO:0000139"
xref: UniProtKB:O94923
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000008021 ! D-glucuronyl C5-epimerase
relationship: has_gene_template HGNC:17855 ! GLCE (human)

[Term]
id: PR:000008021
name: D-glucuronyl C5-epimerase
def: "A protein that is a translation product of the human GLCE gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "GLCE" EXACT PRO-short-label [PRO:DNx]
synonym: "hsepi" EXACT []
synonym: "KIAA0836" RELATED Gene-based []
synonym: "heparan sulfate C5-epimerase" EXACT []
synonym: "heparosan-N-sulfate-glucuronate 5-epimerase" EXACT []
synonym: "heparin/heparan sulfate:glucuronic acid C5-epimerase" EXACT []
is_a: PR:000000001 ! protein