[Term]
id: PR:000039189
name: gap junction alpha-8 protein isoform 1
def: "A gap junction alpha-8 protein that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P28236-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "GJA8/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000007995 ! gap junction alpha-8 protein

[Term]
id: PR:P48165
name: gap junction alpha-8 protein (human)
def: "A gap junction alpha-8 protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:P48165]
comment: Category=organism-gene.
synonym: "GJA8" RELATED Gene-based [UniProtKB:P48165]
synonym: "hGJA8" EXACT PRO-short-label [PRO:DNx]
synonym: "Cx50 (human)" EXACT [UniProtKB:P48165]
synonym: "connexin-50 (human)" EXACT [UniProtKB:P48165]
synonym: "lens fiber protein MP70 (human)" EXACT [UniProtKB:P48165]
xref: UniProtKB:P48165
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000007995 ! gap junction alpha-8 protein
relationship: has_gene_template HGNC:4281 ! GJA8 (human)

[Term]
id: PR:P28236
name: gap junction alpha-8 protein (mouse)
def: "A gap junction alpha-8 protein that is encoded in the genome of mouse." [OMA:P28236, PRO:DNx]
comment: Category=organism-gene.
synonym: "Gja8" RELATED Gene-based [UniProtKB:P28236]
synonym: "mGJA8" EXACT PRO-short-label [PRO:DNx]
synonym: "Cx50 (mouse)" EXACT [UniProtKB:P28236]
synonym: "connexin-50 (mouse)" EXACT [UniProtKB:P28236]
synonym: "lens fiber protein MP70 (mouse)" EXACT [UniProtKB:P28236]
xref: UniProtKB:P28236
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000007995 ! gap junction alpha-8 protein
relationship: has_gene_template MGI:99953 ! Gja8 (mouse)

[Term]
id: PR:P28236-1
name: gap junction alpha-8 protein isoform 1 (mouse)
def: "A gap junction alpha-8 protein isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mGJA8/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P28236-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039189 ! gap junction alpha-8 protein isoform 1

[Term]
id: PR:Q8K4Q9
name: gap junction alpha-8 protein (rat)
def: "A gap junction alpha-8 protein that is encoded in the genome of rat." [OMA:Q8K4Q9, PANTHER:PTHR11984:SF19, PRO:DNx]
comment: Category=organism-gene.
synonym: "Gja8" RELATED Gene-based [UniProtKB:Q8K4Q9]
synonym: "rGJA8" EXACT PRO-short-label [PRO:DNx]
synonym: "Cx50 (rat)" EXACT [UniProtKB:Q8K4Q9]
synonym: "connexin-50 (rat)" EXACT [UniProtKB:Q8K4Q9]
xref: UniProtKB:Q8K4Q9
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000007995 ! gap junction alpha-8 protein
relationship: has_gene_template RGD:628890 ! Gja8 (rat)

[Term]
id: PR:P36381
name: gap junction alpha-8 protein (chicken)
def: "A gap junction alpha-8 protein that is encoded in the genome of chicken." [OMA:P36381, PANTHER:PTHR11984:SF19, PRO:DNx]
comment: Category=organism-gene.
synonym: "GJA8" RELATED Gene-based [UniProtKB:P36381]
synonym: "chick-GJA8" EXACT PRO-short-label [PRO:DNx]
synonym: "Cx45.6 (chicken)" EXACT [UniProtKB:P36381]
synonym: "connexin-45.6 (chicken)" EXACT [UniProtKB:P36381]
xref: UniProtKB:P36381
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000007995 ! gap junction alpha-8 protein
relationship: has_gene_template NCBIGene:395846 ! GJA8 (chicken)

[Term]
id: PR:Q8K4Q9-1
name: gap junction alpha-8 protein isoform 1 (rat)
def: "A gap junction alpha-8 protein isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rGJA8/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8K4Q9-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000039189 ! gap junction alpha-8 protein isoform 1

[Term]
id: PR:000007995
name: gap junction alpha-8 protein
def: "A connexin protein that is a translation product of the human GJA8 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "Cx50" EXACT []
synonym: "GJA8" EXACT PRO-short-label [PRO:DNx]
synonym: "connexin-50" EXACT []
synonym: "lens fiber protein MP70" EXACT []
xref: IUPHARobj:732
is_a: PR:000044679 ! connexin protein

[Term]
id: PR:000047539
name: gap junction alpha-8 protein, initiator methionine removed form (human)
def: "A gap junction alpha-8 protein (human) that has had the initiator methionine removed. UniProtKB:P48165, 2-433." [PRO:DNx, Reactome:R-HSA-190702]
comment: Category=organism-modification.
synonym: "PRO_0000057830" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hGJA8/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P48165, 2-433" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-190702 "PR:000047539 located_in GO:0005789"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P48165 ! gap junction alpha-8 protein (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens