[Term]
id: PR:P10912-4
name: growth hormone receptor isoform h4 (human)
def: "A growth hormone receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10912-4." [PRO:DNx, UniProtKB:P10912]
comment: Category=organism-sequence.
synonym: "hGHR/iso:h4" EXACT PRO-short-label [PRO:DNx]
synonym: "growth hormone receptor isoform GHRd3 (human)" EXACT [UniProtKB:P10912]
xref: UniProtKB:P10912-4
is_a: PR:P10912 ! growth hormone receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P10912
name: growth hormone receptor (human)
def: "A growth hormone receptor that is encoded in the genome of human." [PRO:DNx, UniProtKB:P10912]
comment: Category=organism-gene.
synonym: "GHR" RELATED Gene-based [UniProtKB:P10912]
synonym: "hGHR" EXACT PRO-short-label [PRO:DNx]
synonym: "GH receptor (human)" EXACT [UniProtKB:P10912]
synonym: "somatotropin receptor (human)" EXACT [UniProtKB:P10912]
xref: UniProtKB:P10912
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000007970 ! growth hormone receptor
relationship: has_gene_template HGNC:4263 ! GHR (human)

[Term]
id: PR:P10912-3
name: growth hormone receptor isoform h3 (human)
def: "A growth hormone receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10912-3." [PRO:DNx, UniProtKB:P10912]
comment: Category=organism-sequence.
synonym: "hGHR/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "growth hormone receptor isoform GHR1-277 (human)" EXACT [UniProtKB:P10912]
xref: UniProtKB:P10912-3
is_a: PR:P10912 ! growth hormone receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000054844
name: growth hormone receptor O-glycosylated 1 (human)
def: "A growth hormone receptor (human) that has been O-glycosylated at the residue equivalent to Ser-30 of the amino acid sequence represented by UniProtKB:P10912-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P10912-1, Ser-30, MOD:00002~GNO:G43417UB." [GlyGen:P10912-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hGHR/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10912-1, Ser-30, MOD:00002~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P10912 ! growth hormone receptor (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P10912-2
name: growth hormone receptor isoform h2 (human)
def: "A growth hormone receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10912-2." [PRO:DNx, UniProtKB:P10912]
comment: Category=organism-sequence.
synonym: "hGHR/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "growth hormone receptor isoform GHRtr (human)" EXACT [UniProtKB:P10912]
synonym: "growth hormone receptor isoform GHR1-279 (human)" EXACT [UniProtKB:P10912]
xref: UniProtKB:P10912-2
is_a: PR:P10912 ! growth hormone receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000007970
name: growth hormone receptor
def: "A protein that is a translation product of the human GHR gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "GHR" EXACT PRO-short-label [PRO:DNx]
synonym: "GH receptor" EXACT []
synonym: "somatotropin receptor" EXACT []
xref: IUPHARobj:1720
is_a: PR:000000001 ! protein

[Term]
id: PR:000047529
name: growth hormone receptor, signal peptide removed form (human)
def: "A growth hormone receptor (human) that has had the signal peptide removed. UniProtKB:P10912, 19-638." [PRO:DNx, Reactome:R-HSA-1169263]
comment: Category=organism-modification.
synonym: "hGHR/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000010957" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P10912, 19-638" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-982779 "PR:000047529 located_in GO:0005886"
xref: Reactome:R-HSA-1168385 "PR:000047529 located_in GO:0005886"
xref: Reactome:R-HSA-1169263 "PR:000047529 located_in GO:0031904"
intersection_of: PR:P10912 ! growth hormone receptor (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000047531
name: growth hormone receptor, signal peptide removed phosphorylated 2 (human)
def: "A growth hormone receptor (human) that has had the signal peptide removed and has been post-translationally modified to include phosphotyrosine at positions 332, 487 and 627 of the amino acid sequence represented by UniProtKB:P10912. UniProtKB:P10912, 19-638, Tyr-332/Tyr-487/Tyr-627, MOD:00048." [PRO:DNx, Reactome:R-HSA-1169226]
comment: Category=organism-modification.
synonym: "hGHR/SigPep-/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000010957, Tyr-332/Tyr-487/Tyr-627, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P10912, 19-638, Tyr-332/Tyr-487/Tyr-627, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1169226 "PR:000047531 located_in GO:0005886"
is_a: PR:P10912 ! growth hormone receptor (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:000047530
name: growth hormone receptor, signal peptide removed phosphorylated 1 (human)
def: "A growth hormone receptor (human) that has had the signal peptide removed and has been post-translationally modified to include phosphotyrosine at positions 332, 487, 534, 566 and 627 of the amino acid sequence represented by UniProtKB:P10912. UniProtKB:P10912, 19-638, Tyr-332/Tyr-487/Tyr-534/Tyr-566/Tyr-627, MOD:00048." [PRO:DNx, Reactome:R-HSA-1168904]
comment: Category=organism-modification.
synonym: "hGHR/SigPep-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000010957, Tyr-332/Tyr-487/Tyr-534/Tyr-566/Tyr-627, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P10912, 19-638, Tyr-332/Tyr-487/Tyr-534/Tyr-566/Tyr-627, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1168904 "PR:000047530 located_in GO:0005886"
is_a: PR:P10912 ! growth hormone receptor (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:P10912-1
name: growth hormone receptor isoform h1 (human)
def: "A growth hormone receptor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10912-1." [PRO:DNx, UniProtKB:P10912]
comment: Category=organism-sequence.
synonym: "hGHR/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "growth hormone receptor isoform GHRfl (human)" EXACT [UniProtKB:P10912]
xref: UniProtKB:P10912-1
is_a: PR:P10912 ! growth hormone receptor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens