[Term]
id: PR:000019987
name: vitamin K-dependent gamma-carboxylase, initiator methionine removed form
def: "A vitamin K-dependent gamma-carboxylase that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "GGCX/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000007956 ! vitamin K-dependent gamma-carboxylase
intersection_of: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000056426
name: vitamin K-dependent gamma-carboxylase O-glycosylated 1 (human)
def: "A vitamin K-dependent gamma-carboxylase (human) that has been O-glycosylated at the residue equivalent to Thr-653 of the amino acid sequence represented by UniProtKB:P38435-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P38435-1, Thr-653, MOD:00005~GNO:G43417UB." [GlyGen:P38435-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hGGCX/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P38435-1, Thr-653, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P38435 ! vitamin K-dependent gamma-carboxylase (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P38435-2
name: vitamin K-dependent gamma-carboxylase isoform h2 (human)
def: "A vitamin K-dependent gamma-carboxylase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P38435-2." [PRO:DNx, UniProtKB:P38435]
comment: Category=organism-sequence.
synonym: "hGGCX/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P38435-2
is_a: PR:P38435 ! vitamin K-dependent gamma-carboxylase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P38435-1
name: vitamin K-dependent gamma-carboxylase isoform 1 (human)
def: "A vitamin K-dependent gamma-carboxylase isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hGGCX/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P38435-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039384 ! vitamin K-dependent gamma-carboxylase isoform 1

[Term]
id: PR:000039384
name: vitamin K-dependent gamma-carboxylase isoform 1
def: "A vitamin K-dependent gamma-carboxylase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P38435-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "GGCX/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000007956 ! vitamin K-dependent gamma-carboxylase

[Term]
id: PR:O88496-1
name: vitamin K-dependent gamma-carboxylase isoform 1 (rat)
def: "A vitamin K-dependent gamma-carboxylase isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rGGCX/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O88496-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000039384 ! vitamin K-dependent gamma-carboxylase isoform 1

[Term]
id: PR:O88496
name: vitamin K-dependent gamma-carboxylase (rat)
def: "A vitamin K-dependent gamma-carboxylase that is encoded in the genome of rat." [PANTHER:PTHR12639:SF2, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ggcx" RELATED Gene-based [UniProtKB:O88496]
synonym: "rGGCX" EXACT PRO-short-label [PRO:DNx]
synonym: "gamma-glutamyl carboxylase (rat)" EXACT [UniProtKB:O88496]
synonym: "peptidyl-glutamate 4-carboxylase (rat)" EXACT [UniProtKB:O88496]
synonym: "vitamin K gamma glutamyl carboxylase (rat)" EXACT [UniProtKB:O88496]
xref: UniProtKB:O88496
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000007956 ! vitamin K-dependent gamma-carboxylase
relationship: has_gene_template RGD:68383 ! Ggcx (rat)

[Term]
id: PR:Q9QYC7
name: vitamin K-dependent gamma-carboxylase (mouse)
def: "A vitamin K-dependent gamma-carboxylase that is encoded in the genome of mouse." [OMA:Q9QYC7, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ggcx" RELATED Gene-based [UniProtKB:Q9QYC7]
synonym: "mGGCX" EXACT PRO-short-label [PRO:DNx]
synonym: "gamma-glutamyl carboxylase (mouse)" EXACT [UniProtKB:Q9QYC7]
synonym: "peptidyl-glutamate 4-carboxylase (mouse)" EXACT [UniProtKB:Q9QYC7]
synonym: "vitamin K gamma glutamyl carboxylase (mouse)" EXACT [UniProtKB:Q9QYC7]
xref: UniProtKB:Q9QYC7
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000007956 ! vitamin K-dependent gamma-carboxylase
relationship: has_gene_template MGI:1927655 ! Ggcx (mouse)

[Term]
id: PR:P38435
name: vitamin K-dependent gamma-carboxylase (human)
def: "A vitamin K-dependent gamma-carboxylase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P38435]
comment: Category=organism-gene.
synonym: "GC" RELATED Gene-based [UniProtKB:P38435]
synonym: "GGCX" RELATED Gene-based [UniProtKB:P38435]
synonym: "hGGCX" EXACT PRO-short-label [PRO:DNx]
synonym: "gamma-glutamyl carboxylase (human)" EXACT [UniProtKB:P38435]
synonym: "peptidyl-glutamate 4-carboxylase (human)" EXACT [UniProtKB:P38435]
synonym: "vitamin K gamma glutamyl carboxylase (human)" EXACT [UniProtKB:P38435]
xref: UniProtKB:P38435
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000007956 ! vitamin K-dependent gamma-carboxylase
relationship: has_gene_template HGNC:4247 ! GGCX (human)

[Term]
id: PR:000047526
name: vitamin K-dependent gamma-carboxylase, initiator methionine removed form (human)
def: "A vitamin K-dependent gamma-carboxylase (human) that has had the initiator methionine removed. UniProtKB:P38435, 2-758." [PRO:DNx, Reactome:R-HSA-159860]
comment: Category=organism-modification.
synonym: "PRO_0000191823" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hGGCX/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P38435, 2-758" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-159860 "PR:000047526 located_in GO:0005789"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P38435 ! vitamin K-dependent gamma-carboxylase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000007956
name: vitamin K-dependent gamma-carboxylase
def: "A protein that is a translation product of the human GGCX gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "GC" RELATED Gene-based []
synonym: "GGCX" EXACT PRO-short-label [PRO:DNx]
synonym: "gamma-glutamyl carboxylase" EXACT []
synonym: "peptidyl-glutamate 4-carboxylase" EXACT []
synonym: "vitamin K gamma glutamyl carboxylase" EXACT []
xref: IUPHARobj:1268
is_a: PR:000000001 ! protein