[Term]
id: PR:000027072
name: erythroid transcription factor isoform 1 phosphorylated and sumoylated 1
def: "An erythroid transcription factor isoform 1 that has been phosphorylated in at least a critical Ser residue within the PsiKxExxSP motif (PDSM motif), and enhancing the sumoylation of the Lys residue within that motif. Example: UniProtKB:P15976-1, Lys-137, MOD:01149|Ser-142, MOD:00046." [PMID:16371476, PRO:CNA]
comment: Category=modification.
synonym: "GATA1/iso:1/PhosSumo:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027063 ! erythroid transcription factor isoform 1
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:01149 ! sumoylated lysine

[Term]
id: PR:000027073
name: erythroid transcription factor isoform 1 phosphorylated and sumoylated 1 (human)
def: "An erythroid transcription factor isoform 1 phosphorylated and sumoylated 1 in human. UniProtKB:P15976-1, Lys-137, MOD:01149|Ser-142, MOD:00046." [PMID:16371476, PRO:CNA]
comment: Category=organism-modification.
synonym: "hGATA1/iso:1/PhosSumo:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P15976-1, Lys-137, MOD:01149|Ser-142, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027072 ! erythroid transcription factor isoform 1 phosphorylated and sumoylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:01149 ! sumoylated lysine

[Term]
id: PR:P17679-2
name: erythroid transcription factor isoform 2 (mouse)
def: "An erythroid transcription factor isoform 2 that is encoded in the genome of mouse. This isoform is produced by alternative initiation." [PMID:8524811, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mGATA-1s" EXACT []
synonym: "mGATA1/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P17679-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000027069 ! erythroid transcription factor isoform 2

[Term]
id: PR:P15976-1
name: erythroid transcription factor isoform 1 (human)
def: "An erythroid transcription factor isoform 1 that is encoded in the genome of human." [PRO:HJD]
comment: Category=organism-sequence.
synonym: "hGATA1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P15976-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027063 ! erythroid transcription factor isoform 1

[Term]
id: PR:P15976-2
name: erythroid transcription factor isoform h2 (human)
def: "An erythroid transcription factor (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P15976-2." [PRO:DNx, UniProtKB:P15976]
comment: Category=organism-sequence.
synonym: "hGATA1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P15976-2
is_a: PR:P15976 ! erythroid transcription factor (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P15976
name: erythroid transcription factor (human)
def: "An erythroid transcription factor that is encoded in the genome of human." [PRO:DNx, UniProtKB:P15976]
comment: Category=organism-gene.
synonym: "GF1" RELATED Gene-based [UniProtKB:P15976]
synonym: "ERYF1" RELATED Gene-based [UniProtKB:P15976]
synonym: "GATA1" RELATED Gene-based [UniProtKB:P15976]
synonym: "hGATA1" EXACT PRO-short-label [PRO:DNx]
synonym: "GF-1 (human)" BROAD [UniProtKB:P15976]
synonym: "GATA-1 (human)" EXACT [UniProtKB:P15976]
synonym: "GATA-binding factor 1 (human)" EXACT [UniProtKB:P15976]
synonym: "NF-E1 DNA-binding protein (human)" EXACT [UniProtKB:P15976]
xref: Reactome:R-HSA-996772 "PR:P15976 located_in GO:0005654"
xref: UniProtKB:P15976
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000007857 ! erythroid transcription factor
relationship: has_gene_template HGNC:4170 ! GATA1 (human)

[Term]
id: PR:P43429
name: erythroid transcription factor (rat)
def: "An erythroid transcription factor that is encoded in the genome of rat." [OMA:P43429, PANTHER:PTHR10071:SF26, PRO:DNx]
comment: Category=organism-gene.
synonym: "Gata1" RELATED Gene-based [UniProtKB:P43429]
synonym: "rGATA1" EXACT PRO-short-label [PRO:DNx]
synonym: "GF-1 (rat)" EXACT [UniProtKB:P43429]
synonym: "Eryf1 (rat)" EXACT [UniProtKB:P43429]
synonym: "GATA-1 (rat)" EXACT [UniProtKB:P43429]
synonym: "GATA-binding factor 1 (rat)" EXACT [UniProtKB:P43429]
synonym: "NF-E1 DNA-binding protein (rat)" EXACT [UniProtKB:P43429]
xref: UniProtKB:P43429
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000007857 ! erythroid transcription factor
relationship: has_gene_template RGD:2663 ! Gata1 (rat)

[Term]
id: PR:P15976-3
name: erythroid transcription factor isoform 2 (human)
def: "An erythroid transcription factor isoform 2 that is encoded in the genome of human. This isoform is produced by alternative initiation." [PMID:8524811, PRO:CNA]
comment: Category=organism-sequence.
synonym: "hGATA-1s" EXACT []
synonym: "hGATA1/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P15976-3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027069 ! erythroid transcription factor isoform 2

[Term]
id: PR:P17678
name: erythroid transcription factor (chicken)
def: "An erythroid transcription factor that is encoded in the genome of chicken." [PANTHER:PTHR10071:SF26, PRO:DNx]
comment: Category=organism-gene.
synonym: "ERYF1" RELATED Gene-based [UniProtKB:P17678]
synonym: "GATA1" RELATED Gene-based [UniProtKB:P17678]
synonym: "chick-GATA1" EXACT PRO-short-label [PRO:DNx]
synonym: "Eryf1 (chicken)" EXACT [UniProtKB:P17678]
synonym: "GATA-1 (chicken)" EXACT [UniProtKB:P17678]
synonym: "NF-E1a (chicken)" EXACT [UniProtKB:P17678]
synonym: "GATA-binding factor 1 (chicken)" EXACT [UniProtKB:P17678]
synonym: "NF-E1 DNA-binding protein (chicken)" EXACT [UniProtKB:P17678]
xref: UniProtKB:P17678
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000007857 ! erythroid transcription factor
relationship: has_gene_template CGNC:49811 ! GATA1 (chicken)

[Term]
id: PR:P17679
name: erythroid transcription factor (mouse)
def: "An erythroid transcription factor that is encoded in the genome of mouse." [OMA:P17679, PRO:DNx]
comment: Category=organism-gene.
synonym: "Gf-1" RELATED Gene-based [UniProtKB:P17679]
synonym: "Gata1" RELATED Gene-based [UniProtKB:P17679]
synonym: "mGATA1" EXACT PRO-short-label [PRO:DNx]
synonym: "GF-1 (mouse)" EXACT [UniProtKB:P17679]
synonym: "Eryf1 (mouse)" EXACT [UniProtKB:P17679]
synonym: "GATA-1 (mouse)" EXACT [UniProtKB:P17679]
synonym: "GATA-binding factor 1 (mouse)" EXACT [UniProtKB:P17679]
synonym: "NF-E1 DNA-binding protein (mouse)" EXACT [UniProtKB:P17679]
xref: UniProtKB:P17679
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000007857 ! erythroid transcription factor
relationship: has_gene_template MGI:95661 ! Gata1 (mouse)

[Term]
id: PR:000007857
name: erythroid transcription factor
def: "A protein that is a translation product of the human GATA1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene. Requested by=CL.
synonym: "GF1" RELATED Gene-based []
synonym: "GF-1" RELATED []
synonym: "ERYF1" RELATED Gene-based []
synonym: "Eryf1" EXACT []
synonym: "GATA1" EXACT PRO-short-label [PRO:DNx]
synonym: "GATA-1" EXACT []
synonym: "GATA-binding factor 1" EXACT []
synonym: "NF-E1 DNA-binding protein" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000027069
name: erythroid transcription factor isoform 2
def: "An erythroid transcription factor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P17679-2 or a 1:1 ortholog thereof. This form is created by alternative initiation." [PMID:8524811, PRO:HJD]
comment: Category=sequence.
synonym: "GATA-1s" EXACT []
synonym: "GATA1/iso:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000007857 ! erythroid transcription factor

[Term]
id: PR:000027068
name: erythroid transcription factor isoform 1 sumoylated 1 (mouse)
def: "An erythroid transcription factor isoform 1 sumoylated 1 in mouse. This form has been sumoylated by PIAS4, a SUMO ligase, on the Lys residue within the motif LKTE located within the transactivation domain. UniProtKB:P17679-1, Lys-137, MOD:01149." [PMID:15173587, PRO:HJD]
comment: Category=organism-modification.
synonym: "mGATA1/iso:1/Sumo:1" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P17679-1, Lys-137, MOD:01149" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000027067 ! erythroid transcription factor isoform 1 sumoylated 1
relationship: has_part MOD:01149 ! sumoylated lysine

[Term]
id: PR:P17679-1
name: erythroid transcription factor isoform 1 (mouse)
def: "An erythroid transcription factor isoform 1 that is encoded in the genome of mouse." [PMID:2725678, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mGATA-1" EXACT []
synonym: "mGATA1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P17679-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000027063 ! erythroid transcription factor isoform 1

[Term]
id: PR:000027065
name: erythroid transcription factor isoform 1 phosphorylated 1
def: "An erythroid transcription factor isoform 1 that has been phosphorylated on multiple Ser residues. Example: UniProtKB:P17679-1, Ser-26/Ser-49/Ser-72/Ser-142/Ser-178/Ser-187/Ser-310, MOD:00046." [PMID:8206977, PRO:HJD]
comment: Category=modification.
synonym: "GATA1/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000027063 ! erythroid transcription factor isoform 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000027067
name: erythroid transcription factor isoform 1 sumoylated 1
def: "An erythroid transcription factor isoform 1 that has been post-translationally modified by sumoylation on the Lys residue within the consensus LKxE motif located within the transactivation domain. Example: UniProtKB:P17679-1, Lys-137, MOD:01149." [PMID:15173587, PRO:HJD]
comment: Category=modification. The phosphorylation of a Ser residue in the LKxExxSP motif may be necessary for enhancement of sumoylation (related entry PR:000027072).
synonym: "GATA1/iso:1/Sumo:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000027063 ! erythroid transcription factor isoform 1
relationship: has_part MOD:01149 ! sumoylated lysine

[Term]
id: PR:000027066
name: erythroid transcription factor isoform 1 phosphorylated 1 (mouse)
def: "An erythroid transcription factor isoform 1 phosphorylated 1 in mouse. Phosphorylation of Ser-310 is increased upon inducing erythrocyte maturation. UniProtKB:P17679-1, Ser-26/Ser-49/Ser-72/Ser-142/Ser-178/Ser-187/Ser-310, MOD:00046." [PMID:8206977, PRO:HJD]
comment: Category=organism-modification.
synonym: "mGATA1/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P17679-1, Ser-26/Ser-49/Ser-72/Ser-142/Ser-178/Ser-187/Ser-310, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000027065 ! erythroid transcription factor isoform 1 phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000027063
name: erythroid transcription factor isoform 1
def: "An erythroid transcription factor that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P17679-1 or a 1:1 ortholog thereof." [PMID:2725678, PRO:HJD]
comment: Category=sequence.
synonym: "GATA1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000007857 ! erythroid transcription factor