[Term]
id: PR:Q13480
name: GRB2-associated-binding protein 1 (human)
def: "A GRB2-associated-binding protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13480]
comment: Category=organism-gene.
synonym: "GAB1" RELATED Gene-based [UniProtKB:Q13480]
synonym: "hGAB1" EXACT PRO-short-label [PRO:DNx]
synonym: "GRB2-associated binder 1 (human)" EXACT [UniProtKB:Q13480]
synonym: "growth factor receptor bound protein 2-associated protein 1 (human)" EXACT [UniProtKB:Q13480]
xref: Reactome:R-HSA-179795 "PR:Q13480 located_in GO:0005829"
xref: UniProtKB:Q13480
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000007753 ! GRB2-associated-binding protein 1
relationship: has_gene_template HGNC:4066 ! GAB1 (human)

[Term]
id: PR:000007753
name: GRB2-associated-binding protein 1
def: "A protein that is a translation product of the human GAB1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "GAB1" EXACT PRO-short-label [PRO:DNx]
synonym: "GRB2-associated binder 1" EXACT []
synonym: "growth factor receptor bound protein 2-associated protein 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q13480-2
name: GRB2-associated-binding protein 1 isoform h2 (human)
def: "A GRB2-associated-binding protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13480-2." [PRO:DNx, UniProtKB:Q13480]
comment: Category=organism-sequence.
synonym: "hGAB1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13480-2
is_a: PR:Q13480 ! GRB2-associated-binding protein 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000047485
name: GRB2-associated-binding protein 1 phosphorylated 2 (human)
def: "A GRB2-associated-binding protein 1 (human) that has been post-translationally modified to include phosphotyrosine at positions 627 and 659 of the amino acid sequence represented by UniProtKB:Q13480. UniProtKB:Q13480, Tyr-627/Tyr-659, MOD:00048." [PRO:DNx, Reactome:R-HSA-180496]
comment: Category=organism-modification.
synonym: "hGAB1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q13480, Tyr-627/Tyr-659, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-180496 "PR:000047485 located_in GO:0005829"
is_a: PR:Q13480 ! GRB2-associated-binding protein 1 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000047484
name: GRB2-associated-binding protein 1 phosphorylated 1 (human)
def: "A GRB2-associated-binding protein 1 (human) that has been post-translationally modified to include phosphotyrosine at positions 447, 472, 589, 627 and 659 of the amino acid sequence represented by UniProtKB:Q13480. UniProtKB:Q13480, Tyr-447/Tyr-472/Tyr-589/Tyr-627/Tyr-659, MOD:00048." [PRO:DNx, Reactome:R-HSA-180344]
comment: Category=organism-modification.
synonym: "hGAB1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q13480, Tyr-447/Tyr-472/Tyr-589/Tyr-627/Tyr-659, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-180344 "PR:000047484 located_in GO:0005829"
is_a: PR:Q13480 ! GRB2-associated-binding protein 1 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q13480-1
name: GRB2-associated-binding protein 1 isoform h1 (human)
def: "A GRB2-associated-binding protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13480-1." [PRO:DNx, UniProtKB:Q13480]
comment: Category=organism-sequence.
synonym: "hGAB1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13480-1
is_a: PR:Q13480 ! GRB2-associated-binding protein 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens