[Term]
id: PR:Q9C0B1
name: alpha-ketoglutarate-dependent dioxygenase FTO (human)
def: "An alpha-ketoglutarate-dependent dioxygenase FTO that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9C0B1]
comment: Category=organism-gene.
synonym: "FTO" RELATED Gene-based [UniProtKB:Q9C0B1]
synonym: "hFTO" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA1752" RELATED Gene-based [UniProtKB:Q9C0B1]
synonym: "m6A(m)-demethylase FTO (human)" EXACT [UniProtKB:Q9C0B1]
synonym: "tRNA N1-methyl adenine demethylase FTO (human)" EXACT [UniProtKB:Q9C0B1]
synonym: "fat mass and obesity-associated protein (human)" EXACT [UniProtKB:Q9C0B1]
synonym: "mRNA N(6)-methyladenosine demethylase FTO (human)" EXACT [UniProtKB:Q9C0B1]
synonym: "mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO (human)" EXACT [UniProtKB:Q9C0B1]
synonym: "U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO (human)" EXACT [UniProtKB:Q9C0B1]
synonym: "U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO (human)" EXACT [UniProtKB:Q9C0B1]
xref: UniProtKB:Q9C0B1
xref: Reactome:R-HSA-8857715 "PR:Q9C0B1 located_in GO:0005654"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000007694 ! alpha-ketoglutarate-dependent dioxygenase FTO
relationship: has_gene_template HGNC:24678 ! FTO (human)

[Term]
id: PR:Q9C0B1-4
name: alpha-ketoglutarate-dependent dioxygenase FTO isoform h4 (human)
def: "An alpha-ketoglutarate-dependent dioxygenase FTO (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9C0B1-4." [PRO:DNx, UniProtKB:Q9C0B1]
comment: Category=organism-sequence.
synonym: "hFTO/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9C0B1-4
is_a: PR:Q9C0B1 ! alpha-ketoglutarate-dependent dioxygenase FTO (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000007694
name: alpha-ketoglutarate-dependent dioxygenase FTO
def: "A protein that is a translation product of the human FTO gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "FTO" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA1752" RELATED Gene-based []
synonym: "protein fto" EXACT []
synonym: "protein fatso" EXACT []
synonym: "m6A(m)-demethylase FTO" EXACT []
synonym: "tRNA N1-methyl adenine demethylase FTO" EXACT []
synonym: "fat mass and obesity-associated protein" EXACT []
synonym: "mRNA N(6)-methyladenosine demethylase FTO" EXACT []
synonym: "mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO" EXACT []
synonym: "U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO" EXACT []
synonym: "U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9C0B1-1
name: alpha-ketoglutarate-dependent dioxygenase FTO isoform h1 (human)
def: "An alpha-ketoglutarate-dependent dioxygenase FTO (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9C0B1-1." [PRO:DNx, UniProtKB:Q9C0B1]
comment: Category=organism-sequence.
synonym: "hFTO/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9C0B1-1
is_a: PR:Q9C0B1 ! alpha-ketoglutarate-dependent dioxygenase FTO (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9C0B1-2
name: alpha-ketoglutarate-dependent dioxygenase FTO isoform h2 (human)
def: "An alpha-ketoglutarate-dependent dioxygenase FTO (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9C0B1-2." [PRO:DNx, UniProtKB:Q9C0B1]
comment: Category=organism-sequence.
synonym: "hFTO/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9C0B1-2
is_a: PR:Q9C0B1 ! alpha-ketoglutarate-dependent dioxygenase FTO (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9C0B1-3
name: alpha-ketoglutarate-dependent dioxygenase FTO isoform h3 (human)
def: "An alpha-ketoglutarate-dependent dioxygenase FTO (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9C0B1-3." [PRO:DNx, UniProtKB:Q9C0B1]
comment: Category=organism-sequence.
synonym: "hFTO/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9C0B1-3
is_a: PR:Q9C0B1 ! alpha-ketoglutarate-dependent dioxygenase FTO (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens