[Term] id: PR:Q8BGW1-2 name: alpha-ketoglutarate-dependent dioxygenase FTO isoform m2 (mouse) def: "An alpha-ketoglutarate-dependent dioxygenase FTO (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8BGW1-2." [PRO:DNx, UniProtKB:Q8BGW1] comment: Category=organism-sequence. synonym: "mFTO/iso:m2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8BGW1-2 is_a: PR:Q8BGW1 ! alpha-ketoglutarate-dependent dioxygenase FTO (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q8BGW1-3 name: alpha-ketoglutarate-dependent dioxygenase FTO isoform m3 (mouse) def: "An alpha-ketoglutarate-dependent dioxygenase FTO (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8BGW1-3." [PRO:DNx, UniProtKB:Q8BGW1] comment: Category=organism-sequence. synonym: "mFTO/iso:m3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8BGW1-3 is_a: PR:Q8BGW1 ! alpha-ketoglutarate-dependent dioxygenase FTO (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q8BGW1-1 name: alpha-ketoglutarate-dependent dioxygenase FTO isoform m1 (mouse) def: "An alpha-ketoglutarate-dependent dioxygenase FTO (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8BGW1-1." [PRO:DNx, UniProtKB:Q8BGW1] comment: Category=organism-sequence. synonym: "mFTO/iso:m1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8BGW1-1 is_a: PR:Q8BGW1 ! alpha-ketoglutarate-dependent dioxygenase FTO (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q8BGW1-4 name: alpha-ketoglutarate-dependent dioxygenase FTO isoform m4 (mouse) def: "An alpha-ketoglutarate-dependent dioxygenase FTO (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8BGW1-4." [PRO:DNx, UniProtKB:Q8BGW1] comment: Category=organism-sequence. synonym: "mFTO/iso:m4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8BGW1-4 is_a: PR:Q8BGW1 ! alpha-ketoglutarate-dependent dioxygenase FTO (mouse) relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:Q9C0B1 name: alpha-ketoglutarate-dependent dioxygenase FTO (human) def: "An alpha-ketoglutarate-dependent dioxygenase FTO that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9C0B1] comment: Category=organism-gene. synonym: "FTO" RELATED Gene-based [UniProtKB:Q9C0B1] synonym: "hFTO" EXACT PRO-short-label [PRO:DNx] synonym: "KIAA1752" RELATED Gene-based [UniProtKB:Q9C0B1] synonym: "m6A(m)-demethylase FTO (human)" EXACT [UniProtKB:Q9C0B1] synonym: "tRNA N1-methyl adenine demethylase FTO (human)" EXACT [UniProtKB:Q9C0B1] synonym: "fat mass and obesity-associated protein (human)" EXACT [UniProtKB:Q9C0B1] synonym: "mRNA N(6)-methyladenosine demethylase FTO (human)" EXACT [UniProtKB:Q9C0B1] synonym: "mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO (human)" EXACT [UniProtKB:Q9C0B1] synonym: "U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO (human)" EXACT [UniProtKB:Q9C0B1] synonym: "U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO (human)" EXACT [UniProtKB:Q9C0B1] xref: UniProtKB:Q9C0B1 xref: Reactome:R-HSA-8857715 "PR:Q9C0B1 located_in GO:0005654" intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000007694 ! alpha-ketoglutarate-dependent dioxygenase FTO relationship: has_gene_template HGNC:24678 ! FTO (human) [Term] id: PR:Q9C0B1-4 name: alpha-ketoglutarate-dependent dioxygenase FTO isoform h4 (human) def: "An alpha-ketoglutarate-dependent dioxygenase FTO (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9C0B1-4." [PRO:DNx, UniProtKB:Q9C0B1] comment: Category=organism-sequence. synonym: "hFTO/iso:h4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9C0B1-4 is_a: PR:Q9C0B1 ! alpha-ketoglutarate-dependent dioxygenase FTO (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q2A121 name: alpha-ketoglutarate-dependent dioxygenase FTO (rat) def: "An alpha-ketoglutarate-dependent dioxygenase FTO that is encoded in the genome of rat." [OMA:Q2A121, PRO:DNx] comment: Category=organism-gene. synonym: "Fto" RELATED Gene-based [UniProtKB:Q2A121] synonym: "rFTO" EXACT PRO-short-label [PRO:DNx] synonym: "m6A(m)-demethylase FTO (rat)" EXACT [UniProtKB:Q2A121] synonym: "tRNA N1-methyl adenine demethylase FTO (rat)" EXACT [UniProtKB:Q2A121] synonym: "fat mass and obesity-associated protein (rat)" EXACT [UniProtKB:Q2A121] synonym: "mRNA N(6)-methyladenosine demethylase FTO (rat)" EXACT [UniProtKB:Q2A121] synonym: "mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO (rat)" EXACT [UniProtKB:Q2A121] synonym: "U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO (rat)" EXACT [UniProtKB:Q2A121] synonym: "U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO (rat)" EXACT [UniProtKB:Q2A121] xref: UniProtKB:Q2A121 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000007694 ! alpha-ketoglutarate-dependent dioxygenase FTO relationship: has_gene_template RGD:1305121 ! Fto (rat) [Term] id: PR:Q8BGW1 name: alpha-ketoglutarate-dependent dioxygenase FTO (mouse) def: "An alpha-ketoglutarate-dependent dioxygenase FTO that is encoded in the genome of mouse." [OMA:Q8BGW1, PRO:DNx] comment: Category=organism-gene. synonym: "Fto" RELATED Gene-based [UniProtKB:Q8BGW1] synonym: "mFTO" EXACT PRO-short-label [PRO:DNx] synonym: "Kiaa1752" RELATED Gene-based [UniProtKB:Q8BGW1] synonym: "protein fatso (mouse)" EXACT [UniProtKB:Q8BGW1] synonym: "m6A(m)-demethylase FTO (mouse)" EXACT [UniProtKB:Q8BGW1] synonym: "tRNA N1-methyl adenine demethylase FTO (mouse)" EXACT [UniProtKB:Q8BGW1] synonym: "fat mass and obesity-associated protein (mouse)" EXACT [UniProtKB:Q8BGW1] synonym: "mRNA N(6)-methyladenosine demethylase FTO (mouse)" EXACT [UniProtKB:Q8BGW1] synonym: "mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO (mouse)" EXACT [UniProtKB:Q8BGW1] synonym: "U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO (mouse)" EXACT [UniProtKB:Q8BGW1] synonym: "U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO (mouse)" EXACT [UniProtKB:Q8BGW1] xref: UniProtKB:Q8BGW1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000007694 ! alpha-ketoglutarate-dependent dioxygenase FTO relationship: has_gene_template MGI:1347093 ! Fto (mouse) [Term] id: PR:000007694 name: alpha-ketoglutarate-dependent dioxygenase FTO def: "A protein that is a translation product of the human FTO gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "FTO" EXACT PRO-short-label [PRO:DNx] synonym: "KIAA1752" RELATED Gene-based [] synonym: "protein fto" EXACT [] synonym: "protein fatso" EXACT [] synonym: "m6A(m)-demethylase FTO" EXACT [] synonym: "tRNA N1-methyl adenine demethylase FTO" EXACT [] synonym: "fat mass and obesity-associated protein" EXACT [] synonym: "mRNA N(6)-methyladenosine demethylase FTO" EXACT [] synonym: "mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO" EXACT [] synonym: "U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO" EXACT [] synonym: "U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:Q9C0B1-1 name: alpha-ketoglutarate-dependent dioxygenase FTO isoform h1 (human) def: "An alpha-ketoglutarate-dependent dioxygenase FTO (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9C0B1-1." [PRO:DNx, UniProtKB:Q9C0B1] comment: Category=organism-sequence. synonym: "hFTO/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9C0B1-1 is_a: PR:Q9C0B1 ! alpha-ketoglutarate-dependent dioxygenase FTO (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9C0B1-2 name: alpha-ketoglutarate-dependent dioxygenase FTO isoform h2 (human) def: "An alpha-ketoglutarate-dependent dioxygenase FTO (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9C0B1-2." [PRO:DNx, UniProtKB:Q9C0B1] comment: Category=organism-sequence. synonym: "hFTO/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9C0B1-2 is_a: PR:Q9C0B1 ! alpha-ketoglutarate-dependent dioxygenase FTO (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9C0B1-3 name: alpha-ketoglutarate-dependent dioxygenase FTO isoform h3 (human) def: "An alpha-ketoglutarate-dependent dioxygenase FTO (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9C0B1-3." [PRO:DNx, UniProtKB:Q9C0B1] comment: Category=organism-sequence. synonym: "hFTO/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9C0B1-3 is_a: PR:Q9C0B1 ! alpha-ketoglutarate-dependent dioxygenase FTO (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens