[Term]
id: PR:P42685
name: tyrosine-protein kinase FRK (human)
def: "A tyrosine-protein kinase FRK that is encoded in the genome of human." [PRO:DNx, UniProtKB:P42685]
comment: Category=organism-gene.
synonym: "FRK" RELATED Gene-based [UniProtKB:P42685]
synonym: "RAK" RELATED Gene-based [UniProtKB:P42685]
synonym: "PTK5" RELATED Gene-based [UniProtKB:P42685]
synonym: "hFRK" EXACT PRO-short-label [PRO:DNx]
synonym: "FYN-related kinase (human)" EXACT [UniProtKB:P42685]
synonym: "protein-tyrosine kinase 5 (human)" EXACT [UniProtKB:P42685]
synonym: "nuclear tyrosine protein kinase RAK (human)" EXACT [UniProtKB:P42685]
xref: Reactome:R-HSA-6801037 "PR:P42685 located_in GO:0035580"
xref: Reactome:R-HSA-6806235 "PR:P42685 located_in GO:0005576"
xref: Reactome:R-HSA-6799142 "PR:P42685 located_in GO:0035578"
xref: DTO:03100155
xref: UniProtKB:P42685
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000007664 ! tyrosine-protein kinase FRK
relationship: has_gene_template HGNC:3955 ! FRK (human)

[Term]
id: PR:000007664
name: tyrosine-protein kinase FRK
def: "A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human FRK gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "BSK" EXACT []
synonym: "FRK" EXACT PRO-short-label [PRO:DNx]
synonym: "Iyk" RELATED Gene-based []
synonym: "RAK" RELATED Gene-based []
synonym: "PTK5" RELATED Gene-based []
synonym: "FYN-related kinase" EXACT []
synonym: "intestine tyrosine kinase" EXACT []
synonym: "protein-tyrosine kinase 5" EXACT []
synonym: "nuclear tyrosine protein kinase RAK" EXACT []
synonym: "beta-cell Src-homology tyrosine kinase" EXACT []
xref: IUPHARobj:2025
is_a: PR:000002997 ! proto-oncogene SRC-like tyrosine-protein kinase

[Term]
id: PR:Q922K9
name: tyrosine-protein kinase FRK (mouse)
def: "A tyrosine-protein kinase FRK that is encoded in the genome of mouse." [OMA:Q922K9, PRO:DNx]
comment: Category=organism-gene.
synonym: "Bsk" RELATED Gene-based [UniProtKB:Q922K9]
synonym: "Frk" RELATED Gene-based [UniProtKB:Q922K9]
synonym: "Iyk" RELATED Gene-based [UniProtKB:Q922K9]
synonym: "mFRK" EXACT PRO-short-label [PRO:DNx]
synonym: "BSK (mouse)" EXACT [UniProtKB:Q922K9]
synonym: "FYN-related kinase (mouse)" EXACT [UniProtKB:Q922K9]
synonym: "intestine tyrosine kinase (mouse)" EXACT [UniProtKB:Q922K9]
synonym: "beta-cell Src-homology tyrosine kinase (mouse)" EXACT [UniProtKB:Q922K9]
xref: UniProtKB:Q922K9
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000007664 ! tyrosine-protein kinase FRK
relationship: has_gene_template MGI:103265 ! Frk (mouse)

[Term]
id: PR:Q62662
name: tyrosine-protein kinase FRK (rat)
def: "A tyrosine-protein kinase FRK that is encoded in the genome of rat." [OMA:Q62662, PANTHER:PTHR24418:SF146, PRO:DNx]
comment: Category=organism-gene.
synonym: "Frk" RELATED Gene-based [UniProtKB:Q62662]
synonym: "Gask" RELATED Gene-based [UniProtKB:Q62662]
synonym: "rFRK" EXACT PRO-short-label [PRO:DNx]
synonym: "GTK (rat)" RELATED [UniProtKB:Q62662]
synonym: "GASK (rat)" EXACT [UniProtKB:Q62662]
synonym: "FYN-related kinase (rat)" EXACT [UniProtKB:Q62662]
synonym: "gastrointestinal-associated kinase (rat)" EXACT [UniProtKB:Q62662]
synonym: "gastrointestinal-associated tyrosine kinase (rat)" EXACT [UniProtKB:Q62662]
xref: UniProtKB:Q62662
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000007664 ! tyrosine-protein kinase FRK
relationship: has_gene_template RGD:621423 ! Frk (rat)

[Term]
id: PR:P42685-1
name: tyrosine-protein kinase FRK isoform h1 (human)
def: "A tyrosine-protein kinase FRK (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42685-1." [PRO:DNx, UniProtKB:P42685]
comment: Category=organism-sequence.
synonym: "hFRK/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P42685-1
is_a: PR:P42685 ! tyrosine-protein kinase FRK (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P42685-2
name: tyrosine-protein kinase FRK isoform h2 (human)
def: "A tyrosine-protein kinase FRK (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42685-2." [PRO:DNx, UniProtKB:P42685]
comment: Category=organism-sequence.
synonym: "hFRK/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P42685-2
is_a: PR:P42685 ! tyrosine-protein kinase FRK (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens