[Term]
id: PR:P22830
name: ferrochelatase, mitochondrial (human)
def: "A ferrochelatase, mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:P22830]
comment: Category=organism-gene.
synonym: "FECH" RELATED Gene-based [UniProtKB:P22830]
synonym: "hFECH" EXACT PRO-short-label [PRO:DNx]
synonym: "heme synthase (human)" EXACT [UniProtKB:P22830]
synonym: "protoheme ferro-lyase (human)" EXACT [UniProtKB:P22830]
xref: UniProtKB:P22830
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000007453 ! ferrochelatase, mitochondrial
relationship: has_gene_template HGNC:3647 ! FECH (human)

[Term]
id: PR:000007453
name: ferrochelatase, mitochondrial
def: "A protein that is a translation product of the human FECH gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "FECH" EXACT PRO-short-label [PRO:DNx]
synonym: "heme synthase" BROAD [PRO:DNx]
synonym: "protoheme ferro-lyase" BROAD [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000047396
name: ferrochelatase, mitochondrial, transit peptide removed form (human)
def: "A ferrochelatase, mitochondrial (human) that has had the transit peptide removed. UniProtKB:P22830, 55-423." [PRO:DNx, Reactome:R-HSA-189441]
comment: Category=organism-modification.
synonym: "PRO_0000008873" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hFECH/TransPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P22830, 55-423" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-189441 "PR:000047396 located_in GO:0005759"
intersection_of: PR:P22830 ! ferrochelatase, mitochondrial (human)
intersection_of: lacks_part SO:0000725 ! transit_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P22830-2
name: ferrochelatase, mitochondrial isoform h2 (human)
def: "A ferrochelatase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22830-2." [PRO:DNx, UniProtKB:P22830]
comment: Category=organism-sequence.
synonym: "hFECH/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P22830-2
is_a: PR:P22830 ! ferrochelatase, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P22830-1
name: ferrochelatase, mitochondrial isoform h1 (human)
def: "A ferrochelatase, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22830-1." [PRO:DNx, UniProtKB:P22830]
comment: Category=organism-sequence.
synonym: "hFECH/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P22830-1
is_a: PR:P22830 ! ferrochelatase, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens