[Term]
id: PR:P14324
name: farnesyl pyrophosphate synthase (human)
def: "A farnesyl pyrophosphate synthase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P14324]
comment: Category=organism-gene.
synonym: "FPS" RELATED Gene-based [UniProtKB:P14324]
synonym: "FDPS" RELATED Gene-based [UniProtKB:P14324]
synonym: "hFDPS" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA1293" RELATED Gene-based [UniProtKB:P14324]
synonym: "FPP synthase (human)" EXACT [UniProtKB:P14324]
synonym: "geranyltranstransferase (human)" BROAD [UniProtKB:P14324]
synonym: "dimethylallyltranstransferase (human)" BROAD [UniProtKB:P14324]
synonym: "farnesyl diphosphate synthase (human)" BROAD [UniProtKB:P14324]
synonym: "(2E,6E)-farnesyl diphosphate synthase (human)" BROAD [UniProtKB:P14324]
xref: Reactome:R-HSA-981566 "PR:P14324 located_in GO:0005829"
xref: UniProtKB:P14324
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000007449 ! farnesyl pyrophosphate synthase
relationship: has_gene_template HGNC:3631 ! FDPS (human)

[Term]
id: PR:000007449
name: farnesyl pyrophosphate synthase
def: "A protein that is a translation product of the human FDPS gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "FPS" RELATED Gene-based []
synonym: "FDPS" EXACT PRO-short-label [PRO:DNx]
synonym: "CR 39" EXACT []
synonym: "KIAA1293" RELATED Gene-based []
synonym: "FPP synthase" EXACT []
synonym: "farnesyl diphosphate synthase" RELATED []
synonym: "farnesyl pyrophosphate synthetase" RELATED []
synonym: "cholesterol-regulated 39 kDa protein" EXACT []
xref: IUPHARobj:644
is_a: PR:000000001 ! protein

[Term]
id: PR:P14324-1
name: farnesyl pyrophosphate synthase isoform h1 (human)
def: "A farnesyl pyrophosphate synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P14324-1." [PRO:DNx, UniProtKB:P14324]
comment: Category=organism-sequence.
synonym: "hFDPS/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P14324-1
is_a: PR:P14324 ! farnesyl pyrophosphate synthase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P14324-2
name: farnesyl pyrophosphate synthase isoform 2 (human)
def: "A farnesyl pyrophosphate synthase isoform 2 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hFDPS/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P14324-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038902 ! farnesyl pyrophosphate synthase isoform 2

[Term]
id: PR:000036244
name: farnesyl pyrophosphate synthase acetylated 1 (human)
def: "A farnesyl pyrophosphate synthase (human) that is N-terminal Met acetylated. Example: UniProtKB:P14324-1, Met-1, MOD:00058." [TDR:2338]
comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006).
synonym: "hFDPS/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P14324-1, Met-1, MOD:00058" NARROW PRO-proteoform-std [PRO:DNx]
xref: TDR:2338
is_a: PR:P14324 ! farnesyl pyrophosphate synthase (human)
relationship: has_part MOD:00058 ! N-acetyl-L-methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens