[Term]
id: PR:000038902
name: farnesyl pyrophosphate synthase isoform 2
def: "A farnesyl pyrophosphate synthase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P14324-2 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "FDPS/iso:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000007449 ! farnesyl pyrophosphate synthase

[Term]
id: PR:P05369
name: farnesyl pyrophosphate synthase (rat)
def: "A farnesyl pyrophosphate synthase that is encoded in the genome of rat." [PANTHER:PTHR11525:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Fdps" RELATED Gene-based [UniProtKB:P05369]
synonym: "rFDPS" EXACT PRO-short-label [PRO:DNx]
synonym: "FPS (rat)" EXACT [UniProtKB:P05369]
synonym: "CR 39 (rat)" EXACT [UniProtKB:P05369]
synonym: "FPP synthase (rat)" EXACT [UniProtKB:P05369]
synonym: "geranyltranstransferase (rat)" RELATED [UniProtKB:P05369]
synonym: "dimethylallyltranstransferase (rat)" RELATED [UniProtKB:P05369]
synonym: "farnesyl diphosphate synthase (rat)" RELATED [UniProtKB:P05369]
synonym: "cholesterol-regulated 39 kDa protein (rat)" EXACT [UniProtKB:P05369]
synonym: "(2E,6E)-farnesyl diphosphate synthase (rat)" RELATED [UniProtKB:P05369]
xref: UniProtKB:P05369
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000007449 ! farnesyl pyrophosphate synthase
relationship: has_gene_template RGD:68953 ! Fdps (rat)

[Term]
id: PR:000007449
name: farnesyl pyrophosphate synthase
def: "A protein that is a translation product of the human FDPS gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "FPS" RELATED Gene-based []
synonym: "FDPS" EXACT PRO-short-label [PRO:DNx]
synonym: "CR 39" EXACT []
synonym: "KIAA1293" RELATED Gene-based []
synonym: "FPP synthase" EXACT []
synonym: "farnesyl diphosphate synthase" RELATED []
synonym: "farnesyl pyrophosphate synthetase" RELATED []
synonym: "cholesterol-regulated 39 kDa protein" EXACT []
xref: IUPHARobj:644
is_a: PR:000000001 ! protein

[Term]
id: PR:P14324
name: farnesyl pyrophosphate synthase (human)
def: "A farnesyl pyrophosphate synthase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P14324]
comment: Category=organism-gene.
synonym: "FPS" RELATED Gene-based [UniProtKB:P14324]
synonym: "FDPS" RELATED Gene-based [UniProtKB:P14324]
synonym: "hFDPS" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA1293" RELATED Gene-based [UniProtKB:P14324]
synonym: "FPP synthase (human)" EXACT [UniProtKB:P14324]
synonym: "geranyltranstransferase (human)" BROAD [UniProtKB:P14324]
synonym: "dimethylallyltranstransferase (human)" BROAD [UniProtKB:P14324]
synonym: "farnesyl diphosphate synthase (human)" BROAD [UniProtKB:P14324]
synonym: "(2E,6E)-farnesyl diphosphate synthase (human)" BROAD [UniProtKB:P14324]
xref: Reactome:R-HSA-981566 "PR:P14324 located_in GO:0005829"
xref: UniProtKB:P14324
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000007449 ! farnesyl pyrophosphate synthase
relationship: has_gene_template HGNC:3631 ! FDPS (human)

[Term]
id: PR:000036243
name: farnesyl pyrophosphate synthase acetylated 1 (mouse)
def: "A farnesyl pyrophosphate synthase that is N-terminal Met acetylated in mouse. UniProtKB:Q920E5, Met-1, MOD:00058." [TDR:9281]
comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006).
synonym: "mFDPS/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q920E5, Met-1, MOD:00058" EXACT PRO-proteoform-std [PRO:DNx]
xref: TDR:9281
is_a: PR:000007449 ! farnesyl pyrophosphate synthase
relationship: has_part MOD:00058 ! N-acetyl-L-methionine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:O14230
name: farnesyl pyrophosphate synthase (Schizosaccharomyces pombe 972h-)
def: "A farnesyl pyrophosphate synthase that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:O14230, PANTHER:PTHR11525:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "fps1" RELATED Gene-based [UniProtKB:O14230]
synonym: "SPAC6F12.13c" RELATED Gene-based [UniProtKB:O14230]
synonym: "Spom972h-FDPS" EXACT PRO-short-label [PRO:DNx]
synonym: "FPS (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O14230]
synonym: "FPP synthase (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:O14230]
synonym: "geranyltranstransferase (Schizosaccharomyces pombe 972h-)" RELATED [UniProtKB:O14230]
synonym: "dimethylallyltranstransferase (Schizosaccharomyces pombe 972h-)" RELATED [UniProtKB:O14230]
synonym: "farnesyl diphosphate synthase (Schizosaccharomyces pombe 972h-)" RELATED [UniProtKB:O14230]
synonym: "(2E,6E)-farnesyl diphosphate synthase (Schizosaccharomyces pombe 972h-)" RELATED [UniProtKB:O14230]
xref: UniProtKB:O14230
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000007449 ! farnesyl pyrophosphate synthase
relationship: has_gene_template PomBase:SPAC6F12.13c ! fps1 (Schizosaccharomyces pombe)

[Term]
id: PR:Q920E5
name: farnesyl pyrophosphate synthase (mouse)
def: "A farnesyl pyrophosphate synthase that is encoded in the genome of mouse." [OMA:Q920E5, PRO:DNx]
comment: Category=organism-gene.
synonym: "Fdps" RELATED Gene-based [UniProtKB:Q920E5]
synonym: "mFDPS" EXACT PRO-short-label [PRO:DNx]
synonym: "FPS (mouse)" EXACT [UniProtKB:Q920E5]
synonym: "CR 39 (mouse)" EXACT [UniProtKB:Q920E5]
synonym: "FPP synthase (mouse)" EXACT [UniProtKB:Q920E5]
synonym: "geranyltranstransferase (mouse)" RELATED [UniProtKB:Q920E5]
synonym: "dimethylallyltranstransferase (mouse)" RELATED [UniProtKB:Q920E5]
synonym: "farnesyl diphosphate synthase (mouse)" RELATED [UniProtKB:Q920E5]
synonym: "cholesterol-regulated 39 kDa protein (mouse)" EXACT [UniProtKB:Q920E5]
synonym: "(2E,6E)-farnesyl diphosphate synthase (mouse)" RELATED [UniProtKB:Q920E5]
xref: UniProtKB:Q920E5
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000007449 ! farnesyl pyrophosphate synthase
relationship: has_gene_template MGI:104888 ! Fdps (mouse)

[Term]
id: PR:P08524
name: farnesyl pyrophosphate synthase (yeast)
def: "A farnesyl pyrophosphate synthase that is encoded in the genome of yeast." [OMA:P08524, PANTHER:PTHR11525:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "BOT3" RELATED Gene-based [UniProtKB:P08524]
synonym: "FDS1" RELATED Gene-based [UniProtKB:P08524]
synonym: "FPP1" RELATED Gene-based [UniProtKB:P08524]
synonym: "ERG20" RELATED Gene-based [UniProtKB:P08524]
synonym: "J0525" RELATED Gene-based [UniProtKB:P08524]
synonym: "yFDPS" EXACT PRO-short-label [PRO:DNx]
synonym: "YJL167W" RELATED Gene-based [UniProtKB:P08524]
synonym: "FPS (yeast)" EXACT [UniProtKB:P08524]
synonym: "FPP synthase (yeast)" EXACT [UniProtKB:P08524]
synonym: "geranyltranstransferase (yeast)" RELATED [UniProtKB:P08524]
synonym: "dimethylallyltranstransferase (yeast)" RELATED [UniProtKB:P08524]
synonym: "farnesyl diphosphate synthase (yeast)" RELATED [UniProtKB:P08524]
synonym: "(2E,6E)-farnesyl diphosphate synthase (yeast)" RELATED [UniProtKB:P08524]
xref: UniProtKB:P08524
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000007449 ! farnesyl pyrophosphate synthase
relationship: has_gene_template SGD:S000003703 ! ERG20 (yeast)

[Term]
id: PR:000036244
name: farnesyl pyrophosphate synthase acetylated 1 (human)
def: "A farnesyl pyrophosphate synthase (human) that is N-terminal Met acetylated. Example: UniProtKB:P14324-1, Met-1, MOD:00058." [TDR:2338]
comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006).
synonym: "hFDPS/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P14324-1, Met-1, MOD:00058" NARROW PRO-proteoform-std [PRO:DNx]
xref: TDR:2338
is_a: PR:P14324 ! farnesyl pyrophosphate synthase (human)
relationship: has_part MOD:00058 ! N-acetyl-L-methionine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P14324-2
name: farnesyl pyrophosphate synthase isoform 2 (human)
def: "A farnesyl pyrophosphate synthase isoform 2 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hFDPS/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P14324-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038902 ! farnesyl pyrophosphate synthase isoform 2

[Term]
id: PR:O62336
name: R06C1.2 (worm)
def: "A farnesyl pyrophosphate synthase that is encoded in the genome of worm." [OMA:O62336, PRO:DNx]
comment: Category=organism-gene.
synonym: "FDPS (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "CELE_R06C1.2" RELATED Gene-based [UniProtKB:O62336]
xref: UniProtKB:O62336
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000007449 ! farnesyl pyrophosphate synthase
relationship: has_gene_template WormBase:WBGene00011058 ! fdps-1 (worm)

[Term]
id: PR:P14324-1
name: farnesyl pyrophosphate synthase isoform h1 (human)
def: "A farnesyl pyrophosphate synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P14324-1." [PRO:DNx, UniProtKB:P14324]
comment: Category=organism-sequence.
synonym: "hFDPS/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P14324-1
is_a: PR:P14324 ! farnesyl pyrophosphate synthase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P05369-1
name: farnesyl pyrophosphate synthase isoform 1 (rat)
def: "A farnesyl pyrophosphate synthase isoform 2 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rFDPS/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P05369-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000038902 ! farnesyl pyrophosphate synthase isoform 2

[Term]
id: PR:Q920E5-1
name: farnesyl pyrophosphate synthase isoform 1 (mouse)
def: "A farnesyl pyrophosphate synthase isoform 2 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mFDPS/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q920E5-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000038902 ! farnesyl pyrophosphate synthase isoform 2