[Term]
id: PR:000007448
name: squalene synthase
def: "A protein that is a translation product of the human FDFT1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "SS" EXACT []
synonym: "SQS" EXACT []
synonym: "Erg9" RELATED Gene-based []
synonym: "FDFT1" EXACT PRO-short-label [PRO:DNx]
synonym: "squalene synthetase" EXACT []
synonym: "FPP:FPP farnesyltransferase" EXACT []
synonym: "farnesyl-diphosphate farnesyltransferase" EXACT []
xref: IUPHARobj:645
is_a: PR:000000001 ! protein

[Term]
id: PR:P37268
name: squalene synthase (human)
def: "A squalene synthase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P37268]
comment: Category=organism-gene.
synonym: "FDFT1" RELATED Gene-based [UniProtKB:P37268]
synonym: "hFDFT1" EXACT PRO-short-label [PRO:DNx]
synonym: "SS (human)" EXACT [UniProtKB:P37268]
synonym: "SQS (human)" EXACT [UniProtKB:P37268]
synonym: "FPP:FPP farnesyltransferase (human)" EXACT [UniProtKB:P37268]
synonym: "farnesyl-diphosphate farnesyltransferase (human)" EXACT [UniProtKB:P37268]
synonym: "farnesyl-diphosphate farnesyltransferase 1 (human)" EXACT [UniProtKB:P37268]
xref: Reactome:R-HSA-191369 "PR:P37268 located_in GO:0005789"
xref: UniProtKB:P37268
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000007448 ! squalene synthase
relationship: has_gene_template HGNC:3629 ! FDFT1 (human)

[Term]
id: PR:P37268-4
name: squalene synthase isoform h4 (human)
def: "A squalene synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P37268-4." [PRO:DNx, UniProtKB:P37268]
comment: Category=organism-sequence.
synonym: "hFDFT1/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P37268-4
is_a: PR:P37268 ! squalene synthase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P37268-5
name: squalene synthase isoform h5 (human)
def: "A squalene synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P37268-5." [PRO:DNx, UniProtKB:P37268]
comment: Category=organism-sequence.
synonym: "hFDFT1/iso:h5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P37268-5
is_a: PR:P37268 ! squalene synthase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P37268-2
name: squalene synthase isoform h2 (human)
def: "A squalene synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P37268-2." [PRO:DNx, UniProtKB:P37268]
comment: Category=organism-sequence.
synonym: "hFDFT1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P37268-2
is_a: PR:P37268 ! squalene synthase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P37268-3
name: squalene synthase isoform h3 (human)
def: "A squalene synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P37268-3." [PRO:DNx, UniProtKB:P37268]
comment: Category=organism-sequence.
synonym: "hFDFT1/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P37268-3
is_a: PR:P37268 ! squalene synthase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P37268-1
name: squalene synthase isoform h1 (human)
def: "A squalene synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P37268-1." [PRO:DNx, UniProtKB:P37268]
comment: Category=organism-sequence.
synonym: "hFDFT1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P37268-1
is_a: PR:P37268 ! squalene synthase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens