[Term]
id: PR:000042280
name: acyl-CoA (8-3)-desaturase isoform 1
def: "An acyl-CoA (8-3)-desaturase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q920L1-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "FADS1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000007317 ! acyl-CoA (8-3)-desaturase

[Term]
id: PR:O60427-2
name: acyl-CoA (8-3)-desaturase isoform h2 (human)
def: "An acyl-CoA (8-3)-desaturase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60427-2." [PRO:DNx, UniProtKB:O60427]
comment: Category=organism-sequence.
synonym: "hFADS1/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "acyl-CoA (8-3)-desaturase isoform FADS1AT1 (human)" EXACT [UniProtKB:O60427]
xref: UniProtKB:O60427-2
is_a: PR:O60427 ! acyl-CoA (8-3)-desaturase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q920L1-1
name: fatty acid desaturase 1 isoform 1 (mouse)
def: "An acyl-CoA (8-3)-desaturase isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mFADS1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q920L1-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000042280 ! acyl-CoA (8-3)-desaturase isoform 1

[Term]
id: PR:Q920R3-1
name: fatty acid desaturase 1 isoform 1 (rat)
def: "An acyl-CoA (8-3)-desaturase isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rFADS1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q920R3-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000042280 ! acyl-CoA (8-3)-desaturase isoform 1

[Term]
id: PR:O60427
name: acyl-CoA (8-3)-desaturase (human)
def: "An acyl-CoA (8-3)-desaturase that is encoded in the genome of human." [PRO:DNx, UniProtKB:O60427]
comment: Category=organism-gene.
synonym: "FADS1" RELATED Gene-based [UniProtKB:O60427]
synonym: "FADSD5" RELATED Gene-based [UniProtKB:O60427]
synonym: "hFADS1" EXACT PRO-short-label [PRO:DNx]
synonym: "D5D (human)" EXACT [UniProtKB:O60427]
synonym: "delta-5 desaturase (human)" EXACT [UniProtKB:O60427]
synonym: "Delta(5) desaturase (human)" EXACT [UniProtKB:O60427]
synonym: "fatty acid desaturase 1 (human)" EXACT [UniProtKB:O60427]
synonym: "Delta(5) fatty acid desaturase (human)" EXACT [UniProtKB:O60427]
xref: Reactome:R-HSA-400122 "PR:O60427 located_in GO:0005789"
xref: UniProtKB:O60427
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000007317 ! acyl-CoA (8-3)-desaturase
relationship: has_gene_template HGNC:3574 ! FADS1 (human)

[Term]
id: PR:Q920R3
name: acyl-CoA (8-3)-desaturase (rat)
def: "An acyl-CoA (8-3)-desaturase that is encoded in the genome of rat." [OMA:Q920R3, PRO:DNx]
comment: Category=organism-gene.
synonym: "Fads1" RELATED Gene-based [UniProtKB:Q920R3]
synonym: "rFADS1" EXACT PRO-short-label [PRO:DNx]
synonym: "D5D (rat)" EXACT [UniProtKB:Q920R3]
synonym: "delta-5 desaturase (rat)" EXACT [UniProtKB:Q920R3]
synonym: "Delta(5) desaturase (rat)" EXACT [UniProtKB:Q920R3]
synonym: "fatty acid desaturase 1 (rat)" RELATED [UniProtKB:Q920R3]
synonym: "Delta(5) fatty acid desaturase (rat)" EXACT [UniProtKB:Q920R3]
xref: UniProtKB:Q920R3
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000007317 ! acyl-CoA (8-3)-desaturase
relationship: has_gene_template RGD:621678 ! Fads1 (rat)

[Term]
id: PR:Q920L1
name: acyl-CoA (8-3)-desaturase (mouse)
def: "An acyl-CoA (8-3)-desaturase that is encoded in the genome of mouse." [OMA:Q920L1, PRO:DNx]
comment: Category=organism-gene.
synonym: "Fads1" RELATED Gene-based [UniProtKB:Q920L1]
synonym: "mFADS1" EXACT PRO-short-label [PRO:DNx]
synonym: "D5D (mouse)" EXACT [UniProtKB:Q920L1]
synonym: "delta-5 desaturase (mouse)" EXACT [UniProtKB:Q920L1]
synonym: "Delta(5) desaturase (mouse)" EXACT [UniProtKB:Q920L1]
synonym: "fatty acid desaturase 1 (mouse)" BROAD [UniProtKB:Q920L1]
synonym: "Delta(5) fatty acid desaturase (mouse)" EXACT [UniProtKB:Q920L1]
xref: UniProtKB:Q920L1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000007317 ! acyl-CoA (8-3)-desaturase
relationship: has_gene_template MGI:1923517 ! Fads1 (mouse)

[Term]
id: PR:000007317
name: acyl-CoA (8-3)-desaturase
def: "A protein that is a translation product of the human FADS1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "D5D" EXACT []
synonym: "FADS1" EXACT PRO-short-label [PRO:DNx]
synonym: "FADSD5" RELATED Gene-based []
synonym: "delta-5 desaturase" EXACT []
synonym: "Delta(5) desaturase" EXACT []
synonym: "fatty acid desaturase 1" EXACT []
synonym: "Delta(5) fatty acid desaturase" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:O60427-1
name: acyl-CoA (8-3)-desaturase isoform h1 (human)
def: "An acyl-CoA (8-3)-desaturase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O60427-1." [PRO:DNx, UniProtKB:O60427]
comment: Category=organism-sequence.
synonym: "hFADS1/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "acyl-CoA (8-3)-desaturase isoform FADS1CS (human)" EXACT [UniProtKB:O60427]
xref: UniProtKB:O60427-1
is_a: PR:O60427 ! acyl-CoA (8-3)-desaturase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens