[Term]
id: PR:000047314
name: epidermal growth factor receptor substrate 15 phosphorylated 1 (human)
def: "An epidermal growth factor receptor substrate 15 (human) that has been post-translationally modified to include phosphotyrosine at position 849 of the amino acid sequence represented by UniProtKB:P42566. UniProtKB:P42566, Tyr-849, MOD:00048." [PRO:DAN, Reactome:R-HSA-8867028]
comment: Category=organism-modification. Note: The modified site indicated here (Tyr-849) is referred to as Tyr-850 in some manuscripts. [PRO:DAN, PMID:10953014]
synonym: "hEPS15/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P42566, Tyr-849, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-8867028 "PR:000047314 located_in GO:0005829"
is_a: PR:P42566 ! epidermal growth factor receptor substrate 15 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P42566
name: epidermal growth factor receptor substrate 15 (human)
def: "An epidermal growth factor receptor substrate 15 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P42566]
comment: Category=organism-gene.
synonym: "AF1P" RELATED Gene-based [UniProtKB:P42566]
synonym: "EPS15" RELATED Gene-based [UniProtKB:P42566]
synonym: "hEPS15" EXACT PRO-short-label [PRO:DNx]
synonym: "protein AF-1p (human)" EXACT [UniProtKB:P42566]
synonym: "protein Eps15 (human)" EXACT [UniProtKB:P42566]
xref: Reactome:R-HSA-182920 "PR:P42566 located_in GO:0005829"
xref: UniProtKB:P42566
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000007145 ! epidermal growth factor receptor substrate 15
relationship: has_gene_template HGNC:3419 ! EPS15 (human)

[Term]
id: PR:000007145
name: epidermal growth factor receptor substrate 15
def: "A protein that is a translation product of the human EPS15 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "AF1P" RELATED Gene-based []
synonym: "EPS15" EXACT PRO-short-label [PRO:DNx]
synonym: "protein AF-1p" EXACT []
synonym: "protein Eps15" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P42566-1
name: epidermal growth factor receptor substrate 15 isoform h1 (human)
def: "An epidermal growth factor receptor substrate 15 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42566-1." [PRO:DNx, UniProtKB:P42566]
comment: Category=organism-sequence.
synonym: "hEPS15/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P42566-1
is_a: PR:P42566 ! epidermal growth factor receptor substrate 15 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P42566-2
name: epidermal growth factor receptor substrate 15 isoform h2 (human)
def: "An epidermal growth factor receptor substrate 15 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P42566-2." [PRO:DNx, UniProtKB:P42566]
comment: Category=organism-sequence.
synonym: "hEPS15/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "epidermal growth factor receptor substrate 15 isoform Eps15b (human)" EXACT [UniProtKB:P42566]
xref: UniProtKB:P42566-2
is_a: PR:P42566 ! epidermal growth factor receptor substrate 15 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens