[Term]
id: PR:000006998
name: eukaryotic translation initiation factor 4 gamma 1
def: "A protein that is a translation product of the human EIF4G1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "p220" BROAD [PRO:DNx]
synonym: "EIF4F" RELATED Gene-based []
synonym: "EIF4G" RELATED Gene-based []
synonym: "EIF4G1" EXACT PRO-short-label [PRO:DNx]
synonym: "EIF4GI" RELATED Gene-based []
synonym: "eIF-4G1" EXACT []
synonym: "eIF-4G 1" EXACT []
synonym: "eIF-4-gamma 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q04637
name: eukaryotic translation initiation factor 4 gamma 1 (human)
def: "A eukaryotic translation initiation factor 4 gamma 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q04637]
comment: Category=organism-gene.
synonym: "EIF4F" RELATED Gene-based [UniProtKB:Q04637]
synonym: "EIF4G" RELATED Gene-based [UniProtKB:Q04637]
synonym: "EIF4G1" RELATED Gene-based [UniProtKB:Q04637]
synonym: "EIF4GI" RELATED Gene-based [UniProtKB:Q04637]
synonym: "hEIF4G1" EXACT PRO-short-label [PRO:DNx]
synonym: "p220 (human)" BROAD [UniProtKB:Q04637]
synonym: "eIF-4G1 (human)" EXACT [UniProtKB:Q04637]
synonym: "eIF-4G 1 (human)" EXACT [UniProtKB:Q04637]
synonym: "eIF-4-gamma 1 (human)" EXACT [UniProtKB:Q04637]
xref: UniProtKB:Q04637
xref: Reactome:R-HSA-72584 "PR:Q04637 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006998 ! eukaryotic translation initiation factor 4 gamma 1
relationship: has_gene_template HGNC:3296 ! EIF4G1 (human)

[Term]
id: PR:000047270
name: eukaryotic translation initiation factor 4 gamma 1 phosphorylated 1 (human)
def: "A eukaryotic translation initiation factor 4 gamma 1 (human) that has been post-translationally modified to include phosphoserine at positions 1147, 1187 and 1231 of the amino acid sequence represented by UniProtKB:Q04637. UniProtKB:Q04637, Ser-1147/Ser-1187/Ser-1231, MOD:00046." [PRO:DAN, Reactome:R-HSA-165762]
comment: Category=organism-modification. Note: The modified sites indicated here (Ser-1147/Ser-1187/Ser-1231) are referred to as Ser-1148/Ser-1188/Ser-1232 in some manuscripts. [PRO:DAN, PMID:15314020]
synonym: "hEIF4G1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q04637, Ser-1147/Ser-1187/Ser-1231, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-165762 "PR:000047270 located_in GO:0005829"
is_a: PR:Q04637 ! eukaryotic translation initiation factor 4 gamma 1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q04637-9
name: eukaryotic translation initiation factor 4 gamma 1 isoform h9 (human)
def: "A eukaryotic translation initiation factor 4 gamma 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q04637-9." [PRO:DNx, UniProtKB:Q04637]
comment: Category=organism-sequence.
synonym: "hEIF4G1/iso:h9" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q04637-9
is_a: PR:Q04637 ! eukaryotic translation initiation factor 4 gamma 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q04637-8
name: eukaryotic translation initiation factor 4 gamma 1 isoform h8 (human)
def: "A eukaryotic translation initiation factor 4 gamma 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q04637-8." [PRO:DNx, UniProtKB:Q04637]
comment: Category=organism-sequence.
synonym: "hEIF4G1/iso:h8" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q04637-8
is_a: PR:Q04637 ! eukaryotic translation initiation factor 4 gamma 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q04637-7
name: eukaryotic translation initiation factor 4 gamma 1 isoform h7 (human)
def: "A eukaryotic translation initiation factor 4 gamma 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q04637-7." [PRO:DNx, UniProtKB:Q04637]
comment: Category=organism-sequence.
synonym: "hEIF4G1/iso:h7" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q04637-7
is_a: PR:Q04637 ! eukaryotic translation initiation factor 4 gamma 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q04637-6
name: eukaryotic translation initiation factor 4 gamma 1 isoform E (human)
def: "A eukaryotic translation initiation factor 4 gamma 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q04637-6." [PRO:DNx, UniProtKB:Q04637]
comment: Category=organism-sequence.
synonym: "hEIF4G1/iso:E" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q04637-6
is_a: PR:Q04637 ! eukaryotic translation initiation factor 4 gamma 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q04637-5
name: eukaryotic translation initiation factor 4 gamma 1 isoform D (human)
def: "A eukaryotic translation initiation factor 4 gamma 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q04637-5." [PRO:DNx, UniProtKB:Q04637]
comment: Category=organism-sequence.
synonym: "hEIF4G1/iso:D" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q04637-5
is_a: PR:Q04637 ! eukaryotic translation initiation factor 4 gamma 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q04637-4
name: eukaryotic translation initiation factor 4 gamma 1 isoform C (human)
def: "A eukaryotic translation initiation factor 4 gamma 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q04637-4." [PRO:DNx, UniProtKB:Q04637]
comment: Category=organism-sequence.
synonym: "hEIF4G1/iso:C" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q04637-4
is_a: PR:Q04637 ! eukaryotic translation initiation factor 4 gamma 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q04637-3
name: eukaryotic translation initiation factor 4 gamma 1 isoform B (human)
def: "A eukaryotic translation initiation factor 4 gamma 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q04637-3." [PRO:DNx, UniProtKB:Q04637]
comment: Category=organism-sequence.
synonym: "hEIF4G1/iso:B" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q04637-3
is_a: PR:Q04637 ! eukaryotic translation initiation factor 4 gamma 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q04637-1
name: eukaryotic translation initiation factor 4 gamma 1 isoform A (human)
def: "A eukaryotic translation initiation factor 4 gamma 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q04637-1." [PRO:DNx, UniProtKB:Q04637]
comment: Category=organism-sequence.
synonym: "hEIF4G1/iso:A" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q04637-1
is_a: PR:Q04637 ! eukaryotic translation initiation factor 4 gamma 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens