[Term]
id: PR:000026578
name: eukaryotic translation initiation factor 4E-binding protein 1 isoform 1, initiator methionine removed form
def: "A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "EIF4EBP1/iso:1/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:000026204 ! eukaryotic translation initiation factor 4E-binding protein 1 isoform 1

[Term]
id: PR:Q13541
name: eukaryotic translation initiation factor 4E-binding protein 1 (human)
def: "A eukaryotic translation initiation factor 4E-binding protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13541]
comment: Category=organism-gene.
synonym: "EIF4EBP1" RELATED Gene-based [UniProtKB:Q13541]
synonym: "hEIF4EBP1" EXACT PRO-short-label [PRO:DNx]
synonym: "4E-BP1 (human)" EXACT [UniProtKB:Q13541]
synonym: "PHAS-I (human)" EXACT [UniProtKB:Q13541]
synonym: "eIF4E-binding protein 1 (human)" EXACT [UniProtKB:Q13541]
synonym: "phosphorylated heat- and acid-stable protein regulated by insulin 1 (human)" EXACT [UniProtKB:Q13541]
xref: UniProtKB:Q13541
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006994 ! eukaryotic translation initiation factor 4E-binding protein 1
relationship: has_gene_template HGNC:3288 ! EIF4EBP1 (human)

[Term]
id: PR:Q60876
name: eukaryotic translation initiation factor 4E-binding protein 1 (mouse)
def: "A eukaryotic translation initiation factor 4E-binding protein 1 that is encoded in the genome of mouse." [OMA:Q60876, PRO:DNx]
comment: Category=organism-gene.
synonym: "Eif4ebp1" RELATED Gene-based [UniProtKB:Q60876]
synonym: "mEIF4EBP1" EXACT PRO-short-label [PRO:DNx]
synonym: "4E-BP1 (mouse)" EXACT [UniProtKB:Q60876]
synonym: "PHAS-I (mouse)" EXACT [UniProtKB:Q60876]
synonym: "eIF4E-binding protein 1 (mouse)" EXACT [UniProtKB:Q60876]
synonym: "phosphorylated heat- and acid-stable protein regulated by insulin 1 (mouse)" EXACT [UniProtKB:Q60876]
xref: UniProtKB:Q60876
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000006994 ! eukaryotic translation initiation factor 4E-binding protein 1
relationship: has_gene_template MGI:103267 ! Eif4ebp1 (mouse)

[Term]
id: PR:000026206
name: eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 1
def: "A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 that has been phosphorylated by activated mTORC1. Example: UniProtKB:Q13541-1, 2-118, Thr-37/Thr-46, MOD:00047." [PRO:CNx, Reactome:R-HSA-165685]
comment: Category=modification.
synonym: "4E-BP1-P" RELATED []
synonym: "EIF4EBP1/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000026204 ! eukaryotic translation initiation factor 4E-binding protein 1 isoform 1
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000026204
name: eukaryotic translation initiation factor 4E-binding protein 1 isoform 1
def: "A eukaryotic translation initiation factor 4E-binding protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13541-1 or a 1:1 ortholog thereof." [PRO:CNx]
comment: Category=sequence.
synonym: "EIF4EBP1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000006994 ! eukaryotic translation initiation factor 4E-binding protein 1

[Term]
id: PR:Q62622
name: eukaryotic translation initiation factor 4E-binding protein 1 (rat)
def: "A eukaryotic translation initiation factor 4E-binding protein 1 that is encoded in the genome of rat." [OMA:Q62622, PANTHER:PTHR12669:SF3, PRO:DNx]
comment: Category=organism-gene.
synonym: "Eif4ebp1" RELATED Gene-based [UniProtKB:Q62622]
synonym: "rEIF4EBP1" EXACT PRO-short-label [PRO:DNx]
synonym: "4E-BP1 (rat)" EXACT [UniProtKB:Q62622]
synonym: "PHAS-I (rat)" EXACT [UniProtKB:Q62622]
synonym: "eIF4E-binding protein 1 (rat)" EXACT [UniProtKB:Q62622]
synonym: "phosphorylated heat- and acid-stable protein regulated by insulin 1 (rat)" EXACT [UniProtKB:Q62622]
xref: UniProtKB:Q62622
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000006994 ! eukaryotic translation initiation factor 4E-binding protein 1
relationship: has_gene_template RGD:620259 ! Eif4ebp1 (rat)

[Term]
id: PR:Q60876-1
name: eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 (mouse)
def: "A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNx]
comment: Category=organism-sequence.
synonym: "mEIF4EBP1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q60876-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000026204 ! eukaryotic translation initiation factor 4E-binding protein 1 isoform 1

[Term]
id: PR:000006994
name: eukaryotic translation initiation factor 4E-binding protein 1
def: "A protein that is a translation product of the human EIF4EBP1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "4E-BP1" EXACT []
synonym: "PHAS-I" EXACT []
synonym: "EIF4EBP1" EXACT PRO-short-label [PRO:DNx]
synonym: "eIF4E-binding protein 1" EXACT []
synonym: "phosphorylated heat- and acid-stable protein regulated by insulin 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000044855
name: eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed acetylated and phosphorylated 2 (human)
def: "A eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed form (human) that is acetylated at the N-terminal Ser and phosphorylated on Ser-94 and Ser-101. UniProtKB:Q13541, 2-118, Ser-2, MOD:00060|Ser-94/Ser-101, MOD:00046." [TDR:2642]
comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006).
synonym: "hEIF4EBP1/InitMet-/AcPhos:2" EXACT PRO-short-label [PRO:DAN]
synonym: "PRO_0000190513, Ser-2, MOD:00060|Ser-94/Ser-101, MOD:00046" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q13541, 2-118, Ser-2, MOD:00060|Ser-94/Ser-101, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: TDR:2642
is_a: PR:000028425 ! eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed form (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00060 ! N-acetyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000019769
name: eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed form
def: "A eukaryotic translation initiation factor 4E-binding protein 1 that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "EIF4EBP1/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000006994 ! eukaryotic translation initiation factor 4E-binding protein 1
intersection_of: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:000029017
name: eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 2
def: "A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 that has been phosphorylated by MAP kinases. Example: UniProtKB:Q62622-1, Ser-64, MOD:00046." [PMID:7939721, PRO:CNA]
comment: Category=modification.
synonym: "EIF4EBP1/iso:1/Phos:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000026204 ! eukaryotic translation initiation factor 4E-binding protein 1 isoform 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000029018
name: eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 2 (rat)
def: "A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 2 in rat. UniProtKB:Q62622-1, Ser-64, MOD:00046." [PMID:7939721, PRO:CNA]
comment: Category=organism-modification. Kinase=("MAPK"; PR:000000019).
synonym: "rEIF4EBP1/iso:1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "PHAS-I phosphorylated (rat)" RELATED []
synonym: "UniProtKB:Q62622-1, Ser-64, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000029017 ! eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 2
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000035490
name: eukaryotic translation initiation factor 4E-binding protein 1 phosphorylated 1 (human)
def: "A eukaryotic translation initiation factor 4E-binding protein 1 phosphorylated 1 in human." [PMID:10198256, PRO:KER]
comment: Category=organism-modification. Kinase=("BUB1"; PR:O43683).
synonym: "hEIF4EBP1/Phos:1" EXACT PRO-short-label [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000035489 ! eukaryotic translation initiation factor 4E-binding protein 1 phosphorylated 1
relationship: has_part MOD:00696 ! phosphorylated residue

[Term]
id: PR:000044853
name: eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed acetylated 1 (human)
def: "A eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed form (human) that is acetylated at the N-terminal Ser. UniProtKB:Q13541, 2-118, Ser-2, MOD:00060." [PRO:DAN, TDR:2130]
comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006).
synonym: "hEIF4EBP1/InitMet-/Ac:1" EXACT PRO-short-label [PRO:DAN]
synonym: "PRO_0000190513, Ser-2, MOD:00060" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q13541, 2-118, Ser-2, MOD:00060" EXACT PRO-proteoform-std [PRO:DNx]
xref: TDR:2130
is_a: PR:000028425 ! eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed form (human)
relationship: has_part MOD:00060 ! N-acetyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q6PFS8
name: uncharacterized protein, eif4ebp1 translation product (zebrafish)
def: "A eukaryotic translation initiation factor 4E-binding protein 1 that is encoded in the genome of zebrafish." [PRO:DNx]
comment: Category=organism-gene.
synonym: "z-EIF4EBP1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q6PFS8
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000006994 ! eukaryotic translation initiation factor 4E-binding protein 1
relationship: has_gene_template ZFIN:ZDB-GENE-030131-2332 ! eif4ebp1 (zebrafish)

[Term]
id: PR:000035489
name: eukaryotic translation initiation factor 4E-binding protein 1 phosphorylated 1
def: "A eukaryotic translation initiation factor 4E-binding protein 1 that has been post-translationally modified by BUB1." [PMID:10198256, PRO:KER]
comment: Category=modification.
synonym: "EIF4EBP1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000006994 ! eukaryotic translation initiation factor 4E-binding protein 1
relationship: has_part MOD:00696 ! phosphorylated residue

[Term]
id: PR:000026216
name: eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 1 (human)
def: "A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 1 in human. UniProtKB:Q13541-1, 2-118, Thr-37/Thr-46, MOD:00047." [PRO:CNx, Reactome:R-HSA-165685]
comment: Category=organism-modification.
synonym: "hEIF4EBP1/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000190513, Thr-37/Thr-46, MOD:00047" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q13541-1, 2-118, Thr-37/Thr-46, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-165685 "PR:000026216 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026206 ! eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 phosphorylated 1
relationship: has_part MOD:00047 ! O-phospho-L-threonine

[Term]
id: PR:000044854
name: eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed acetylated and phosphorylated 1 (human)
def: "A eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed form (human) that is acetylated at the N-terminal Ser and phosphorylated on Ser-94. UniProtKB:Q13541, 2-118, Ser-2, MOD:00060|Ser-94, MOD:00046." [PRO:DAN, TDR:2640]
comment: Category=organism-modification. Note: Top down proteomics. Evidence=(ECO:0000006).
synonym: "hEIF4EBP1/InitMet-/AcPhos:1" EXACT PRO-short-label [PRO:DAN]
synonym: "PRO_0000190513, Ser-2, MOD:00060|Ser-94, MOD:00046" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q13541, 2-118, Ser-2, MOD:00060|Ser-94, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: TDR:2640
is_a: PR:000028425 ! eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed form (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00060 ! N-acetyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000028425
name: eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed form (human)
def: "A eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed form in human. UniProtKB:Q13541, 2-118." [PRO:DNx]
comment: Category=organism-modification.
synonym: "PRO_0000190513" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hEIF4EBP1/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q13541, 2-118" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-72580 "PR:000028425 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000019769 ! eukaryotic translation initiation factor 4E-binding protein 1, initiator methionine removed form

[Term]
id: PR:Q13541-1
name: eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 (human)
def: "A eukaryotic translation initiation factor 4E-binding protein 1 isoform 1 that is encoded in the genome of human." [PRO:CNx]
comment: Category=organism-sequence.
synonym: "hEIF4EBP1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13541-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026204 ! eukaryotic translation initiation factor 4E-binding protein 1 isoform 1