[Term]
id: PR:000047265
name: translation initiation factor eIF-2B subunit epsilon, initiator methionine removed form (human)
def: "A translation initiation factor eIF-2B subunit epsilon (human) that has had the initiator methionine removed. UniProtKB:Q13144, 2-721." [PRO:DNx, Reactome:R-HSA-72523]
comment: Category=organism-modification.
synonym: "PRO_0000156073" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hEIF2B5/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q13144, 2-721" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-72523 "PR:000047265 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:Q13144 ! translation initiation factor eIF-2B subunit epsilon (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000006966
name: translation initiation factor eIF-2B subunit epsilon
def: "A protein that is a translation product of the human EIF2B5 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "EIF2B5" EXACT PRO-short-label [PRO:DNx]
synonym: "EIF2BE" RELATED Gene-based []
synonym: "eIF-2B GDP-GTP exchange factor subunit epsilon" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q64350
name: translation initiation factor eIF-2B subunit epsilon (rat)
def: "A translation initiation factor eIF-2B subunit epsilon that is encoded in the genome of rat." [OMA:Q64350, PANTHER:PTHR22572:SF7, PRO:DNx]
comment: Category=organism-gene.
synonym: "Eif2b5" RELATED Gene-based [UniProtKB:Q64350]
synonym: "Eif2be" RELATED Gene-based [UniProtKB:Q64350]
synonym: "rEIF2B5" EXACT PRO-short-label [PRO:DNx]
synonym: "eIF-2B GDP-GTP exchange factor subunit epsilon (rat)" EXACT [UniProtKB:Q64350]
xref: UniProtKB:Q64350
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000006966 ! translation initiation factor eIF-2B subunit epsilon
relationship: has_gene_template RGD:708380 ! Eif2b5 (rat)

[Term]
id: PR:000019758
name: translation initiation factor eIF-2B subunit epsilon, initiator methionine removed form
def: "A translation initiation factor eIF-2B subunit epsilon that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "EIF2B5/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000006966 ! translation initiation factor eIF-2B subunit epsilon
intersection_of: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:Q54RF3
name: translation initiation factor eIF-2B subunit epsilon (Dictyostelium discoideum)
def: "A translation initiation factor eIF-2B subunit epsilon that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54RF3, PANTHER:PTHR22572:SF7, PRO:DNx]
comment: Category=organism-gene.
synonym: "eif2b5" RELATED Gene-based [UniProtKB:Q54RF3]
synonym: "DDB_G0283163" RELATED Gene-based [UniProtKB:Q54RF3]
synonym: "Dicty-EIF2B5" EXACT PRO-short-label [PRO:DNx]
synonym: "eIF-2B GDP-GTP exchange factor subunit epsilon (Dictyostelium discoideum)" EXACT [UniProtKB:Q54RF3]
xref: UniProtKB:Q54RF3
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000006966 ! translation initiation factor eIF-2B subunit epsilon
relationship: has_gene_template dictyBase:DDB_G0283163 ! eif2b5 (Dictyostelium discoideum)

[Term]
id: PR:P32501
name: translation initiation factor eIF-2B subunit epsilon (yeast)
def: "A translation initiation factor eIF-2B subunit epsilon that is encoded in the genome of yeast." [OMA:P32501, PANTHER:PTHR22572:SF7, PRO:DNx]
comment: Category=organism-gene.
synonym: "GCD6" RELATED Gene-based [UniProtKB:P32501]
synonym: "TIF225" RELATED Gene-based [UniProtKB:P32501]
synonym: "YDR211W" RELATED Gene-based [UniProtKB:P32501]
synonym: "yEIF2B5" EXACT PRO-short-label [PRO:DNx]
synonym: "YD8142.12" RELATED Gene-based [UniProtKB:P32501]
synonym: "YD8142B.03" RELATED Gene-based [UniProtKB:P32501]
synonym: "GCD complex subunit GCD6 (yeast)" EXACT [UniProtKB:P32501]
synonym: "eIF-2B GDP-GTP exchange factor subunit epsilon (yeast)" EXACT [UniProtKB:P32501]
synonym: "guanine nucleotide exchange factor subunit GCD6 (yeast)" EXACT [UniProtKB:P32501]
xref: UniProtKB:P32501
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000006966 ! translation initiation factor eIF-2B subunit epsilon
relationship: has_gene_template SGD:S000002619 ! GCD6 (yeast)

[Term]
id: PR:000045899
name: translation initiation factor eIF-2B subunit epsilon phosphorylated 1 (human)
def: "A translation initiation factor eIF-2B subunit epsilon (human) that has been phosphorylated at Ser-540. UniProtKB:Q13144, Ser-540, MOD:00046." [PMID:9468292, iPTMnet:Q13144]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:9468292). Status=unreviewed.
synonym: "hEIF2B5/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q13144, Ser-540, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:Q13144 ! translation initiation factor eIF-2B subunit epsilon (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q13144
name: translation initiation factor eIF-2B subunit epsilon (human)
def: "A translation initiation factor eIF-2B subunit epsilon that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13144]
comment: Category=organism-gene.
synonym: "EIF2B5" RELATED Gene-based [UniProtKB:Q13144]
synonym: "EIF2BE" RELATED Gene-based [UniProtKB:Q13144]
synonym: "hEIF2B5" EXACT PRO-short-label [PRO:DNx]
synonym: "eIF-2B GDP-GTP exchange factor subunit epsilon (human)" EXACT [UniProtKB:Q13144]
xref: UniProtKB:Q13144
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006966 ! translation initiation factor eIF-2B subunit epsilon
relationship: has_gene_template HGNC:3261 ! EIF2B5 (human)

[Term]
id: PR:Q8CHW4
name: translation initiation factor eIF-2B subunit epsilon (mouse)
def: "A translation initiation factor eIF-2B subunit epsilon that is encoded in the genome of mouse." [OMA:Q8CHW4, PRO:DNx]
comment: Category=organism-gene.
synonym: "Eif2b5" RELATED Gene-based [UniProtKB:Q8CHW4]
synonym: "mEIF2B5" EXACT PRO-short-label [PRO:DNx]
synonym: "eIF-2B GDP-GTP exchange factor subunit epsilon (mouse)" EXACT [UniProtKB:Q8CHW4]
xref: UniProtKB:Q8CHW4
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000006966 ! translation initiation factor eIF-2B subunit epsilon
relationship: has_gene_template MGI:2446176 ! Eif2b5 (mouse)

[Term]
id: PR:P56287
name: probable translation initiation factor eIF-2B subunit epsilon (Schizosaccharomyces pombe 972h-)
def: "A translation initiation factor eIF-2B subunit epsilon that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:P56287, PANTHER:PTHR22572:SF7, PRO:DNx]
comment: Category=organism-gene.
synonym: "tif225" RELATED Gene-based [UniProtKB:P56287]
synonym: "SPAC8C9.15c" RELATED Gene-based [UniProtKB:P56287]
synonym: "Spom972h-EIF2B5" EXACT PRO-short-label [PRO:DNx]
synonym: "eIF-2B GDP-GTP exchange factor subunit epsilon (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P56287]
xref: UniProtKB:P56287
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000006966 ! translation initiation factor eIF-2B subunit epsilon
relationship: has_gene_template PomBase:SPAC8C9.15c ! tif225 (Schizosaccharomyces pombe)