[Term]
id: PR:000006961
name: eIF-2-alpha kinase GCN2
def: "A protein that is a translation product of the human EIF2AK4 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "GCN2" RELATED Gene-based []
synonym: "EIF2AK4" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA1338" RELATED Gene-based []
synonym: "GCN2-like protein" EXACT []
synonym: "eukaryotic translation initiation factor 2-alpha kinase 4" EXACT []
xref: IUPHARobj:2018
is_a: PR:000000001 ! protein

[Term]
id: PR:P15442
name: eIF-2-alpha kinase GCN2 (yeast)
def: "An eIF-2-alpha kinase GCN2 that is encoded in the genome of yeast." [OMA:P15442, PRO:DNx]
comment: Category=organism-gene.
synonym: "AAS1" RELATED Gene-based [UniProtKB:P15442]
synonym: "GCN2" RELATED Gene-based [UniProtKB:P15442]
synonym: "YDR283C" RELATED Gene-based [UniProtKB:P15442]
synonym: "yEIF2AK4" EXACT PRO-short-label [PRO:DNx]
synonym: "serine/threonine-protein kinase GCN2 (yeast)" EXACT [UniProtKB:P15442]
synonym: "general control non-derepressible protein 2 (yeast)" EXACT [UniProtKB:P15442]
xref: UniProtKB:P15442
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000006961 ! eIF-2-alpha kinase GCN2
relationship: has_gene_template SGD:S000002691 ! GCN2 (yeast)

[Term]
id: PR:000046144
name: eIF-2-alpha kinase GCN2 phosphorylated 1 (yeast)
def: "An eIF-2-alpha kinase GCN2 (yeast) that has been phosphorylated at Ser-577. UniProtKB:P15442, Ser-577, MOD:00046." [PMID:12070158, iPTMnet:P15442]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:12070158). Status=unreviewed.
synonym: "yEIF2AK4/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P15442, Ser-577, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P15442 ! eIF-2-alpha kinase GCN2 (yeast)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C