[Term]
id: PR:P22388-1
name: endothelin-1 isoform 1 (rat)
def: "An endothelin-1 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rEDN1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P22388-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000039072 ! endothelin-1 isoform 1

[Term]
id: PR:000019734
name: endothelin-1 proteolytic cleavage product
def: "An endothelin-1 that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "EDN1/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000006897 ! endothelin-1

[Term]
id: PR:000006897
name: endothelin-1
def: "A protein that is a translation product of the human EDN1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "EDN1" EXACT PRO-short-label [PRO:DNx]
synonym: "ET-1" EXACT []
synonym: "PPET1" EXACT []
synonym: "preproendothelin-1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P22387-1
name: endothelin-1 isoform 1 (mouse)
def: "An endothelin-1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mEDN1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P22387-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039072 ! endothelin-1 isoform 1

[Term]
id: PR:P22387
name: endothelin-1 (mouse)
def: "An endothelin-1 that is encoded in the genome of mouse." [OMA:P22387, PRO:DNx]
comment: Category=organism-gene.
synonym: "Edn1" RELATED Gene-based [UniProtKB:P22387]
synonym: "mEDN1" EXACT PRO-short-label [PRO:DNx]
synonym: "ET-1 (mouse)" EXACT [UniProtKB:P22387]
synonym: "PPET1 (mouse)" EXACT [UniProtKB:P22387]
synonym: "preproendothelin-1 (mouse)" EXACT [UniProtKB:P22387]
xref: UniProtKB:P22387
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000006897 ! endothelin-1
relationship: has_gene_template MGI:95283 ! Edn1 (mouse)

[Term]
id: PR:P22388
name: endothelin-1 (rat)
def: "An endothelin-1 that is encoded in the genome of rat." [OMA:P22388, PANTHER:PTHR13874:SF3, PRO:DNx]
comment: Category=organism-gene.
synonym: "Edn1" RELATED Gene-based [UniProtKB:P22388]
synonym: "rEDN1" EXACT PRO-short-label [PRO:DNx]
synonym: "ET-1 (rat)" EXACT [UniProtKB:P22388]
synonym: "PPET1 (rat)" EXACT [UniProtKB:P22388]
synonym: "preproendothelin-1 (rat)" EXACT [UniProtKB:P22388]
xref: UniProtKB:P22388
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000006897 ! endothelin-1
relationship: has_gene_template RGD:2532 ! Edn1 (rat)

[Term]
id: PR:000019733
name: endothelin-1, signal peptide removed form
def: "An endothelin-1 that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "EDN1/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000006897 ! endothelin-1
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:P05305
name: endothelin-1 (human)
def: "An endothelin-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P05305]
comment: Category=organism-gene.
synonym: "EDN1" RELATED Gene-based [UniProtKB:P05305]
synonym: "hEDN1" EXACT PRO-short-label [PRO:DNx]
synonym: "PPET1 (human)" EXACT [UniProtKB:P05305]
synonym: "preproendothelin-1 (human)" EXACT [UniProtKB:P05305]
xref: UniProtKB:P05305
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006897 ! endothelin-1
relationship: has_gene_template HGNC:3176 ! EDN1 (human)

[Term]
id: PR:000039072
name: endothelin-1 isoform 1
def: "An endothelin-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P22387-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "EDN1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000006897 ! endothelin-1