[Term]
id: PR:Q9BQ95
name: evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (human)
def: "An evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9BQ95]
comment: Category=organism-gene.
synonym: "ECSIT" RELATED Gene-based [UniProtKB:Q9BQ95]
synonym: "hECSIT" EXACT PRO-short-label [PRO:DNx]
synonym: "protein SITPEC (human)" EXACT [UniProtKB:Q9BQ95]
xref: UniProtKB:Q9BQ95
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006884 ! evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
relationship: has_gene_template HGNC:29548 ! ECSIT (human)

[Term]
id: PR:Q9U6M0
name: evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (fruit fly)
def: "An evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial that is encoded in the genome of fruit fly." [OMA:Q9U6M0, PANTHER:PTHR13113:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "ECSIT" RELATED Gene-based [UniProtKB:Q9U6M0]
synonym: "CG10610" RELATED Gene-based [UniProtKB:Q9U6M0]
synonym: "fly-ECSIT" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9U6M0
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000006884 ! evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
relationship: has_gene_template FlyBase:FBgn0028436 ! ECSIT (fruit fly)

[Term]
id: PR:Q9QZH6
name: evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (mouse)
def: "An evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial that is encoded in the genome of mouse." [OMA:Q9QZH6, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ecsit" RELATED Gene-based [UniProtKB:Q9QZH6]
synonym: "Sitpec" RELATED Gene-based [UniProtKB:Q9QZH6]
synonym: "mECSIT" EXACT PRO-short-label [PRO:DNx]
synonym: "protein SITPEC (mouse)" EXACT [UniProtKB:Q9QZH6]
xref: UniProtKB:Q9QZH6
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000006884 ! evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
relationship: has_gene_template MGI:1349469 ! Ecsit (mouse)

[Term]
id: PR:000047241
name: evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial, transit peptide removed form (human)
def: "An evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (human) that has had the transit peptide removed. UniProtKB:Q9BQ95, 49-431." [PRO:DNx, Reactome:R-HSA-168064, Reactome:R-HSA-5689047]
comment: Category=organism-modification.
synonym: "PRO_0000291985" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hECSIT/TransPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9BQ95, 49-431" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-168064 "PR:000047241 located_in GO:0005829"
xref: Reactome:R-HSA-5689047 "PR:000047241 located_in GO:0005743"
intersection_of: PR:Q9BQ95 ! evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (human)
intersection_of: lacks_part SO:0000725 ! transit_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9BQ95-2
name: evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial isoform h2 (human)
def: "An evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BQ95-2." [PRO:DNx, UniProtKB:Q9BQ95]
comment: Category=organism-sequence.
synonym: "hECSIT/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9BQ95-2
is_a: PR:Q9BQ95 ! evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q08CK1
name: evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (zebrafish)
def: "An evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial that is encoded in the genome of zebrafish." [OMA:Q08CK1, PANTHER:PTHR13113:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "ecsit" RELATED Gene-based [UniProtKB:Q08CK1]
synonym: "z-ECSIT" EXACT PRO-short-label [PRO:DNx]
synonym: "zgc:152999" RELATED Gene-based [UniProtKB:Q08CK1]
xref: UniProtKB:Q08CK1
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000006884 ! evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
relationship: has_gene_template ZFIN:ZDB-GENE-030131-1332 ! ecsit (zebrafish)

[Term]
id: PR:000006884
name: evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
def: "A protein that is a translation product of the human ECSIT gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ECSIT" EXACT PRO-short-label [PRO:DNx]
synonym: "Sitpec" RELATED Gene-based []
synonym: "protein SITPEC" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9BQ95-4
name: evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial isoform h4 (human)
def: "An evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BQ95-4." [PRO:DNx, UniProtKB:Q9BQ95]
comment: Category=organism-sequence.
synonym: "hECSIT/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9BQ95-4
is_a: PR:Q9BQ95 ! evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9BQ95-3
name: evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial isoform h3 (human)
def: "An evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BQ95-3." [PRO:DNx, UniProtKB:Q9BQ95]
comment: Category=organism-sequence.
synonym: "hECSIT/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9BQ95-3
is_a: PR:Q9BQ95 ! evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q5XIC2
name: evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (rat)
def: "An evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial that is encoded in the genome of rat." [OMA:Q5XIC2, PANTHER:PTHR13113:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ecsit" RELATED Gene-based [UniProtKB:Q5XIC2]
synonym: "rECSIT" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q5XIC2
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000006884 ! evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
relationship: has_gene_template RGD:1359488 ! Ecsit (rat)

[Term]
id: PR:Q9BQ95-1
name: evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial isoform h1 (human)
def: "An evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BQ95-1." [PRO:DNx, UniProtKB:Q9BQ95]
comment: Category=organism-sequence.
synonym: "hECSIT/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9BQ95-1
is_a: PR:Q9BQ95 ! evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens