[Term]
id: PR:Q92630-2
name: dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform h2 (human)
def: "A dual specificity tyrosine-phosphorylation-regulated kinase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92630-2." [PRO:DNx, UniProtKB:Q92630]
comment: Category=organism-sequence.
synonym: "hDYRK2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q92630-2
is_a: PR:Q92630 ! dual specificity tyrosine-phosphorylation-regulated kinase 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q92630-1
name: dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform h1 (human)
def: "A dual specificity tyrosine-phosphorylation-regulated kinase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92630-1." [PRO:DNx, UniProtKB:Q92630]
comment: Category=organism-sequence.
synonym: "hDYRK2/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q92630-1
is_a: PR:Q92630 ! dual specificity tyrosine-phosphorylation-regulated kinase 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000006783
name: dual specificity tyrosine-phosphorylation-regulated kinase 2
def: "A protein that is a translation product of the human DYRK2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "DYRK2" EXACT PRO-short-label [PRO:DNx]
xref: IUPHARobj:2011
is_a: PR:000000001 ! protein

[Term]
id: PR:Q92630
name: dual specificity tyrosine-phosphorylation-regulated kinase 2 (human)
def: "A dual specificity tyrosine-phosphorylation-regulated kinase 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q92630]
comment: Category=organism-gene.
synonym: "DYRK2" RELATED Gene-based [UniProtKB:Q92630]
synonym: "hDYRK2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q92630
xref: Reactome:R-HSA-3215037 "PR:Q92630 located_in GO:0005654"
xref: DTO:03100115
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006783 ! dual specificity tyrosine-phosphorylation-regulated kinase 2
relationship: has_gene_template HGNC:3093 ! DYRK2 (human)

[Term]
id: PR:000047230
name: dual specificity tyrosine-phosphorylation-regulated kinase 2 phosphorylated 1 (human)
def: "A dual specificity tyrosine-phosphorylation-regulated kinase 2 (human) that has been post-translationally modified to include phosphothreonine at position 106, and phosphoserine at position 442 of the amino acid sequence represented by UniProtKB:Q92630. UniProtKB:Q92630, Thr-106, MOD:00047|Ser-442, MOD:00046." [PRO:DNx, Reactome:R-HSA-6798368]
comment: Category=organism-modification.
synonym: "hDYRK2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q92630, Thr-106, MOD:00047|Ser-442, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-6798368 "PR:000047230 located_in GO:0005654"
is_a: PR:Q92630 ! dual specificity tyrosine-phosphorylation-regulated kinase 2 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000047231
name: dual specificity tyrosine-phosphorylation-regulated kinase 2 ubiquitinated form (human)
def: "A dual specificity tyrosine-phosphorylation-regulated kinase 2 (human) that includes at least one ubiquitinated lysine. UniProtKB:Q92630, MOD:01148." [PRO:DNx, Reactome:R-HSA-6798383]
comment: Category=organism-modification.
synonym: "hDYRK2/UbiqLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q92630, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-6798383 "PR:000047231 located_in GO:0005654"
intersection_of: has_part MOD:01148 ! ubiquitinylated lysine
intersection_of: PR:Q92630 ! dual specificity tyrosine-phosphorylation-regulated kinase 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens