[Term]
id: PR:000006782
name: dual specificity tyrosine-phosphorylation-regulated kinase 1B
def: "A protein that is a translation product of the human DYRK1B gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "MIRK" RELATED Gene-based []
synonym: "DYRK1B" EXACT PRO-short-label [PRO:DNx]
synonym: "mirk protein kinase" EXACT []
synonym: "minibrain-related kinase" EXACT []
xref: IUPHARobj:2010
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9Y463
name: dual specificity tyrosine-phosphorylation-regulated kinase 1B (human)
def: "A dual specificity tyrosine-phosphorylation-regulated kinase 1B that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9Y463]
comment: Category=organism-gene.
synonym: "MIRK" RELATED Gene-based [UniProtKB:Q9Y463]
synonym: "DYRK1B" RELATED Gene-based [UniProtKB:Q9Y463]
synonym: "hDYRK1B" EXACT PRO-short-label [PRO:DNx]
synonym: "Mirk protein kinase (human)" EXACT [UniProtKB:Q9Y463]
synonym: "minibrain-related kinase (human)" EXACT [UniProtKB:Q9Y463]
xref: UniProtKB:Q9Y463
xref: DTO:03100114
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006782 ! dual specificity tyrosine-phosphorylation-regulated kinase 1B
relationship: has_gene_template HGNC:3092 ! DYRK1B (human)

[Term]
id: PR:Q9Y463-1
name: dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform 1 (human)
def: "A dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence. Requested by=PubChem.
synonym: "hDYRK1B/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Y463-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000044203 ! dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform 1

[Term]
id: PR:Q9Y463-2
name: dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform 2 (human)
def: "A dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform 2 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hDYRK1B/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Y463-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000044204 ! dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform 2

[Term]
id: PR:Q9Y463-3
name: dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform h3 (human)
def: "A dual specificity tyrosine-phosphorylation-regulated kinase 1B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y463-3." [PRO:DNx, UniProtKB:Q9Y463]
comment: Category=organism-sequence.
synonym: "hDYRK1B/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Y463-3
is_a: PR:Q9Y463 ! dual specificity tyrosine-phosphorylation-regulated kinase 1B (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045520
name: dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform 1 phosphorylated 1 (human)
def: "A dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform 1 (human) that has been phosphorylated at Ser-421 by autocatalysis. UniProtKB:Q9Y463-1, Ser-421, MOD:00046." [PMID:26346493, PRO:CNA]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:26346493). Kinase=("DYRK1B"; PR:Q9Y463; Ser-421). Note: Proteoform created based on papers selected via the RLIMS-P text mining tool.
synonym: "hDYRK1B/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9Y463-1, Ser-421, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9Y463-1 ! dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform 1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens