[Term] id: PR:000006727 name: dual oxidase 1 def: "A protein that is a translation product of the human DUOX1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "DUOX" RELATED Gene-based [] synonym: "DUOX1" EXACT PRO-short-label [PRO:DNx] synonym: "LNOX1" RELATED Gene-based [] synonym: "THOX1" RELATED Gene-based [] synonym: "long NOX 1" EXACT [] synonym: "large NOX 1" EXACT [] synonym: "thyroid oxidase 1" EXACT [] synonym: "NADPH thyroid oxidase 1" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:000047220 name: dual oxidase 1, signal peptide removed form (human) def: "A dual oxidase 1 (human) that has had the signal peptide removed. UniProtKB:Q9NRD9, 22-1551." [PRO:DNx, Reactome:R-HSA-5693694] comment: Category=organism-modification. synonym: "PRO_0000223344" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hDUOX1/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q9NRD9, 22-1551" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5693694 "PR:000047220 located_in GO:0005886" intersection_of: PR:Q9NRD9 ! dual oxidase 1 (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9NRD9 name: dual oxidase 1 (human) def: "A dual oxidase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9NRD9] comment: Category=organism-gene. synonym: "DUOX" RELATED Gene-based [UniProtKB:Q9NRD9] synonym: "DUOX1" RELATED Gene-based [UniProtKB:Q9NRD9] synonym: "LNOX1" RELATED Gene-based [UniProtKB:Q9NRD9] synonym: "THOX1" RELATED Gene-based [UniProtKB:Q9NRD9] synonym: "hDUOX1" EXACT PRO-short-label [PRO:DNx] synonym: "long NOX 1 (human)" EXACT [UniProtKB:Q9NRD9] synonym: "large NOX 1 (human)" EXACT [UniProtKB:Q9NRD9] synonym: "thyroid oxidase 1 (human)" EXACT [UniProtKB:Q9NRD9] synonym: "NADPH thyroid oxidase 1 (human)" EXACT [UniProtKB:Q9NRD9] xref: UniProtKB:Q9NRD9 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000006727 ! dual oxidase 1 relationship: has_gene_template HGNC:3062 ! DUOX1 (human) [Term] id: PR:Q9NRD9-2 name: dual oxidase 1 isoform h2 (human) def: "A dual oxidase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NRD9-2." [PRO:DNx, UniProtKB:Q9NRD9] comment: Category=organism-sequence. synonym: "hDUOX1/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9NRD9-2 is_a: PR:Q9NRD9 ! dual oxidase 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q9NRD9-1 name: dual oxidase 1 isoform 1 (human) def: "A dual oxidase 1 isoform 1 that is encoded in the genome of human." [PRO:DNx] comment: Category=organism-sequence. synonym: "hDUOX1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9NRD9-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000043520 ! dual oxidase 1 isoform 1