[Term]
id: PR:Q9NRD9
name: dual oxidase 1 (human)
def: "A dual oxidase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9NRD9]
comment: Category=organism-gene.
synonym: "DUOX" RELATED Gene-based [UniProtKB:Q9NRD9]
synonym: "DUOX1" RELATED Gene-based [UniProtKB:Q9NRD9]
synonym: "LNOX1" RELATED Gene-based [UniProtKB:Q9NRD9]
synonym: "THOX1" RELATED Gene-based [UniProtKB:Q9NRD9]
synonym: "hDUOX1" EXACT PRO-short-label [PRO:DNx]
synonym: "long NOX 1 (human)" EXACT [UniProtKB:Q9NRD9]
synonym: "large NOX 1 (human)" EXACT [UniProtKB:Q9NRD9]
synonym: "thyroid oxidase 1 (human)" EXACT [UniProtKB:Q9NRD9]
synonym: "NADPH thyroid oxidase 1 (human)" EXACT [UniProtKB:Q9NRD9]
xref: UniProtKB:Q9NRD9
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006727 ! dual oxidase 1
relationship: has_gene_template HGNC:3062 ! DUOX1 (human)

[Term]
id: PR:Q8CIY2
name: dual oxidase 1 (rat)
def: "A dual oxidase 1 that is encoded in the genome of rat." [OMA:Q8CIY2, PANTHER:PTHR11972:SF1, PRO:DNx]
comment: Category=organism-gene.
synonym: "Duox1" RELATED Gene-based [UniProtKB:Q8CIY2]
synonym: "rDUOX1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8CIY2
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000006727 ! dual oxidase 1
relationship: has_gene_template RGD:628760 ! Duox1 (rat)

[Term]
id: PR:000006727
name: dual oxidase 1
def: "A protein that is a translation product of the human DUOX1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "DUOX" RELATED Gene-based []
synonym: "DUOX1" EXACT PRO-short-label [PRO:DNx]
synonym: "LNOX1" RELATED Gene-based []
synonym: "THOX1" RELATED Gene-based []
synonym: "long NOX 1" EXACT []
synonym: "large NOX 1" EXACT []
synonym: "thyroid oxidase 1" EXACT []
synonym: "NADPH thyroid oxidase 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q8CIY2-1
name: dual oxidase 1 isoform 1 (rat)
def: "A dual oxidase 1 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rDUOX1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8CIY2-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000043520 ! dual oxidase 1 isoform 1

[Term]
id: PR:Q9NRD9-1
name: dual oxidase 1 isoform 1 (human)
def: "A dual oxidase 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hDUOX1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9NRD9-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000043520 ! dual oxidase 1 isoform 1

[Term]
id: PR:Q9VQH2
name: dual oxidase (fruit fly)
def: "A dual oxidase 1 that is encoded in the genome of fruit fly." [OMA:Q9VQH2, PRO:DNx]
comment: Category=organism-gene.
synonym: "Duox" RELATED Gene-based [UniProtKB:Q9VQH2]
synonym: "CG3131" RELATED Gene-based [UniProtKB:Q9VQH2]
synonym: "fly-DUOX1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9VQH2
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000006727 ! dual oxidase 1
relationship: has_gene_template FlyBase:FBgn0283531 ! Duox (fruit fly)

[Term]
id: PR:000047220
name: dual oxidase 1, signal peptide removed form (human)
def: "A dual oxidase 1 (human) that has had the signal peptide removed. UniProtKB:Q9NRD9, 22-1551." [PRO:DNx, Reactome:R-HSA-5693694]
comment: Category=organism-modification.
synonym: "PRO_0000223344" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hDUOX1/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9NRD9, 22-1551" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5693694 "PR:000047220 located_in GO:0005886"
intersection_of: PR:Q9NRD9 ! dual oxidase 1 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9NRD9-2
name: dual oxidase 1 isoform h2 (human)
def: "A dual oxidase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NRD9-2." [PRO:DNx, UniProtKB:Q9NRD9]
comment: Category=organism-sequence.
synonym: "hDUOX1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9NRD9-2
is_a: PR:Q9NRD9 ! dual oxidase 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000043520
name: dual oxidase 1 isoform 1
def: "A dual oxidase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NRD9-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "DUOX1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000006727 ! dual oxidase 1