[Term]
id: PR:P36957
name: dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (human)
def: "A dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:P36957]
comment: Category=organism-gene.
synonym: "DLST" RELATED Gene-based [UniProtKB:P36957]
synonym: "DLTS" RELATED Gene-based [UniProtKB:P36957]
synonym: "hDLST" EXACT PRO-short-label [PRO:DNx]
synonym: "E2K (human)" EXACT [UniProtKB:P36957]
synonym: "OGDC-E2 (human)" EXACT [UniProtKB:P36957]
synonym: "2-oxoglutarate dehydrogenase complex component E2 (human)" EXACT [UniProtKB:P36957]
synonym: "dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex (human)" EXACT [UniProtKB:P36957]
xref: UniProtKB:P36957
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006526 ! dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
relationship: has_gene_template HGNC:2911 ! DLST (human)

[Term]
id: PR:000006526
name: dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial
def: "A protein that is a translation product of the human DLST gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "E2K" EXACT []
synonym: "DLST" EXACT PRO-short-label [PRO:DNx]
synonym: "DLTS" RELATED Gene-based []
synonym: "OGDC-E2" BROAD [PRO:DNx]
synonym: "2-oxoglutarate dehydrogenase complex component E2" BROAD [PRO:DNx]
synonym: "dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex" BROAD [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000047187
name: dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial, transit peptide removed form (human)
def: "A dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (human) that has had the transit peptide removed. UniProtKB:P36957, 68-453." [PRO:DNx, Reactome:R-HSA-6792574]
comment: Category=organism-modification.
synonym: "PRO_0000020472" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hDLST/TransPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P36957, 68-453" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-6792574 "PR:000047187 located_in GO:0005759"
intersection_of: PR:P36957 ! dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (human)
intersection_of: lacks_part SO:0000725 ! transit_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000047188
name: dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial, transit peptide removed lipoylated 1 (human)
def: "A dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (human) that has had the transit peptide removed and has been post-translationally modified to include lipoylated lysine at position 110 of the amino acid sequence represented by UniProtKB:P36957. UniProtKB:P36957, 68-453, Lys-110, MOD:00127." [PRO:DNx, Reactome:R-HSA-69993]
comment: Category=organism-modification.
synonym: "hDLST/TransPep-/Lipo:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000020472, Lys-110, MOD:00127" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P36957, 68-453, Lys-110, MOD:00127" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-69993 "PR:000047188 located_in GO:0005759"
is_a: PR:P36957 ! dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (human)
relationship: has_part MOD:00127 ! N6-lipoyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part SO:0000725 ! transit_peptide

[Term]
id: PR:P36957-1
name: dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial isoform h1 (human)
def: "A dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P36957-1." [PRO:DNx, UniProtKB:P36957]
comment: Category=organism-sequence.
synonym: "hDLST/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P36957-1
is_a: PR:P36957 ! dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P36957-2
name: dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial isoform h2 (human)
def: "A dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P36957-2." [PRO:DNx, UniProtKB:P36957]
comment: Category=organism-sequence.
synonym: "hDLST/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P36957-2
is_a: PR:P36957 ! dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens