[Term]
id: PR:P55073
name: thyroxine 5-deiodinase (human)
def: "A thyroxine 5-deiodinase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P55073]
comment: Category=organism-gene.
synonym: "DIO3" RELATED Gene-based [UniProtKB:P55073]
synonym: "ITDI3" RELATED Gene-based [UniProtKB:P55073]
synonym: "TXDI3" RELATED Gene-based [UniProtKB:P55073]
synonym: "hDIO3" EXACT PRO-short-label [PRO:DNx]
synonym: "5DIII (human)" EXACT [UniProtKB:P55073]
synonym: "DIOIII (human)" EXACT [UniProtKB:P55073]
synonym: "type 3 DI (human)" EXACT [UniProtKB:P55073]
synonym: "type III iodothyronine deiodinase (human)" EXACT [UniProtKB:P55073]
xref: UniProtKB:P55073
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006482 ! thyroxine 5-deiodinase
relationship: has_gene_template HGNC:2885 ! DIO3 (human)

[Term]
id: PR:000042275
name: thyroxine 5-deiodinase isoform 1
def: "A thyroxine 5-deiodinase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q91ZI8-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "DIO3/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000006482 ! thyroxine 5-deiodinase

[Term]
id: PR:P49897-1
name: type III iodothyronine deiodinase isoform 1 (rat)
def: "A thyroxine 5-deiodinase isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rDIO3/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P49897-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000042275 ! thyroxine 5-deiodinase isoform 1

[Term]
id: PR:Q91ZI8
name: thyroxine 5-deiodinase (mouse)
def: "A thyroxine 5-deiodinase that is encoded in the genome of mouse." [OMA:Q91ZI8, PRO:DNx]
comment: Category=organism-gene.
synonym: "Dio3" RELATED Gene-based [UniProtKB:Q91ZI8]
synonym: "mDIO3" EXACT PRO-short-label [PRO:DNx]
synonym: "5DIII (mouse)" EXACT [UniProtKB:Q91ZI8]
synonym: "DIOIII (mouse)" EXACT [UniProtKB:Q91ZI8]
synonym: "type 3 DI (mouse)" EXACT [UniProtKB:Q91ZI8]
synonym: "type III iodothyronine deiodinase (mouse)" EXACT [UniProtKB:Q91ZI8]
xref: UniProtKB:Q91ZI8
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000006482 ! thyroxine 5-deiodinase
relationship: has_gene_template MGI:1306782 ! Dio3 (mouse)

[Term]
id: PR:O42412
name: thyroxine 5-deiodinase (chicken)
def: "A thyroxine 5-deiodinase that is encoded in the genome of chicken." [PANTHER:PTHR11781:SF4, PRO:DNx]
comment: Category=organism-gene.
synonym: "DIO3" RELATED Gene-based [UniProtKB:O42412]
synonym: "chick-DIO3" EXACT PRO-short-label [PRO:DNx]
synonym: "5DIII (chicken)" EXACT [UniProtKB:O42412]
synonym: "DIOIII (chicken)" EXACT [UniProtKB:O42412]
synonym: "type 3 DI (chicken)" EXACT [UniProtKB:O42412]
synonym: "type III iodothyronine deiodinase (chicken)" EXACT [UniProtKB:O42412]
xref: UniProtKB:O42412
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000006482 ! thyroxine 5-deiodinase
relationship: has_gene_template CGNC:66218 ! DIO3 (chicken)

[Term]
id: PR:Q91ZI8-1
name: type III iodothyronine deiodinase isoform 1 (mouse)
def: "A thyroxine 5-deiodinase isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mDIO3/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q91ZI8-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000042275 ! thyroxine 5-deiodinase isoform 1

[Term]
id: PR:P49897
name: thyroxine 5-deiodinase (rat)
def: "A thyroxine 5-deiodinase that is encoded in the genome of rat." [PANTHER:PTHR11781:SF4, PRO:DNx]
comment: Category=organism-gene.
synonym: "Dio3" RELATED Gene-based [UniProtKB:P49897]
synonym: "Itdi3" RELATED Gene-based [UniProtKB:P49897]
synonym: "Txdi3" RELATED Gene-based [UniProtKB:P49897]
synonym: "rDIO3" EXACT PRO-short-label [PRO:DNx]
synonym: "5DIII (rat)" EXACT [UniProtKB:P49897]
synonym: "DIOIII (rat)" EXACT [UniProtKB:P49897]
synonym: "type 3 DI (rat)" EXACT [UniProtKB:P49897]
synonym: "type III iodothyronine deiodinase (rat)" EXACT [UniProtKB:P49897]
xref: UniProtKB:P49897
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000006482 ! thyroxine 5-deiodinase
relationship: has_gene_template RGD:68420 ! Dio3 (rat)

[Term]
id: PR:000006482
name: thyroxine 5-deiodinase
def: "A protein that is a translation product of the human DIO3 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "DIO3" EXACT PRO-short-label [PRO:DNx]
synonym: "5DIII" EXACT []
synonym: "ITDI3" RELATED Gene-based []
synonym: "TXDI3" RELATED Gene-based []
synonym: "DIOIII" EXACT []
synonym: "type 3 DI" EXACT []
synonym: "type-III 5'-deiodinase" EXACT []
synonym: "type III iodothyronine deiodinase" EXACT []
xref: IUPHARobj:2483
is_a: PR:000000001 ! protein