[Term]
id: PR:Q9Z1Y9
name: type II iodothyronine deiodinase (mouse)
def: "A type II iodothyronine deiodinase that is encoded in the genome of mouse." [OMA:Q9Z1Y9, PRO:DNx]
comment: Category=organism-gene.
synonym: "Dio2" RELATED Gene-based [UniProtKB:Q9Z1Y9]
synonym: "mDIO2" EXACT PRO-short-label [PRO:DNx]
synonym: "5DII (mouse)" EXACT [UniProtKB:Q9Z1Y9]
synonym: "DIOII (mouse)" EXACT [UniProtKB:Q9Z1Y9]
synonym: "type 2 DI (mouse)" EXACT [UniProtKB:Q9Z1Y9]
synonym: "type-II 5'-deiodinase (mouse)" EXACT [UniProtKB:Q9Z1Y9]
xref: UniProtKB:Q9Z1Y9
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000006481 ! type II iodothyronine deiodinase
relationship: has_gene_template MGI:1338833 ! Dio2 (mouse)

[Term]
id: PR:Q92813
name: type II iodothyronine deiodinase (human)
def: "A type II iodothyronine deiodinase that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q92813]
comment: Category=organism-gene.
synonym: "DIO2" RELATED Gene-based [UniProtKB:Q92813]
synonym: "ITDI2" RELATED Gene-based [UniProtKB:Q92813]
synonym: "TXDI2" RELATED Gene-based [UniProtKB:Q92813]
synonym: "hDIO2" EXACT PRO-short-label [PRO:DNx]
synonym: "5DII (human)" EXACT [UniProtKB:Q92813]
synonym: "DIOII (human)" EXACT [UniProtKB:Q92813]
synonym: "type 2 DI (human)" EXACT [UniProtKB:Q92813]
synonym: "type-II 5'-deiodinase (human)" EXACT [UniProtKB:Q92813]
xref: UniProtKB:Q92813
xref: Reactome:R-HSA-2980836 "PR:Q92813 located_in GO:0005886"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006481 ! type II iodothyronine deiodinase
relationship: has_gene_template HGNC:2884 ! DIO2 (human)

[Term]
id: PR:Q92813-1
name: type II iodothyronine deiodinase isoform h1 (human)
def: "A type II iodothyronine deiodinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92813-1." [PRO:DNx, UniProtKB:Q92813]
comment: Category=organism-sequence.
synonym: "hDIO2/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "type II iodothyronine deiodinase isoform hDII-a (human)" EXACT [UniProtKB:Q92813]
xref: UniProtKB:Q92813-1
is_a: PR:Q92813 ! type II iodothyronine deiodinase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q92813-2
name: type II iodothyronine deiodinase isoform h2 (human)
def: "A type II iodothyronine deiodinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92813-2." [PRO:DNx, UniProtKB:Q92813]
comment: Category=organism-sequence.
synonym: "hDIO2/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "type II iodothyronine deiodinase isoform hDII-b (human)" EXACT [UniProtKB:Q92813]
xref: UniProtKB:Q92813-2
is_a: PR:Q92813 ! type II iodothyronine deiodinase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q92813-3
name: type II iodothyronine deiodinase isoform h3 (human)
def: "A type II iodothyronine deiodinase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92813-3." [PRO:DNx, UniProtKB:Q92813]
comment: Category=organism-sequence.
synonym: "hDIO2/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "type II iodothyronine deiodinase isoform hDII-c (human)" EXACT [UniProtKB:Q92813]
xref: UniProtKB:Q92813-3
is_a: PR:Q92813 ! type II iodothyronine deiodinase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P70551-1
name: type II iodothyronine deiodinase isoform 1 (rat)
def: "A type II iodothyronine deiodinase isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rDIO2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P70551-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000044338 ! type II iodothyronine deiodinase isoform 1

[Term]
id: PR:000044338
name: type II iodothyronine deiodinase isoform 1
def: "A type II iodothyronine deiodinase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Z1Y9-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "DIO2/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000006481 ! type II iodothyronine deiodinase

[Term]
id: PR:Q9Z1Y9-1
name: type II iodothyronine deiodinase isoform 1 (mouse)
def: "A type II iodothyronine deiodinase isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mDIO2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Z1Y9-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000044338 ! type II iodothyronine deiodinase isoform 1

[Term]
id: PR:P70551
name: type II iodothyronine deiodinase (rat)
def: "A type II iodothyronine deiodinase that is encoded in the genome of rat." [PANTHER:PTHR11781:SF3, PRO:DNx]
comment: Category=organism-gene.
synonym: "Dio2" RELATED Gene-based [UniProtKB:P70551]
synonym: "Itdi2" RELATED Gene-based [UniProtKB:P70551]
synonym: "Txdi2" RELATED Gene-based [UniProtKB:P70551]
synonym: "rDIO2" EXACT PRO-short-label [PRO:DNx]
synonym: "5DII (rat)" EXACT [UniProtKB:P70551]
synonym: "DIOII (rat)" EXACT [UniProtKB:P70551]
synonym: "type 2 DI (rat)" EXACT [UniProtKB:P70551]
synonym: "type-II 5'-deiodinase (rat)" EXACT [UniProtKB:P70551]
xref: UniProtKB:P70551
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000006481 ! type II iodothyronine deiodinase
relationship: has_gene_template RGD:68418 ! Dio2 (rat)

[Term]
id: PR:000006481
name: type II iodothyronine deiodinase
def: "A protein that is a translation product of the human DIO2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "5DII" EXACT []
synonym: "DIO2" EXACT PRO-short-label [PRO:DNx]
synonym: "DIOII" EXACT []
synonym: "ITDI2" RELATED Gene-based []
synonym: "TXDI2" RELATED Gene-based []
synonym: "type 2 DI" EXACT []
synonym: "type-II 5'-deiodinase" EXACT []
xref: IUPHARobj:2482
is_a: PR:000000001 ! protein