[Term]
id: PR:Q9BUN8
name: derlin-1 (human)
def: "A derlin-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9BUN8]
comment: Category=organism-gene.
synonym: "DER1" RELATED Gene-based [UniProtKB:Q9BUN8]
synonym: "DERL1" RELATED Gene-based [UniProtKB:Q9BUN8]
synonym: "hDERL1" EXACT PRO-short-label [PRO:DNx]
synonym: "UNQ243/PRO276" RELATED Gene-based [UniProtKB:Q9BUN8]
synonym: "DERtrin-1 (human)" EXACT [UniProtKB:Q9BUN8]
synonym: "Der1-like protein 1 (human)" EXACT [UniProtKB:Q9BUN8]
synonym: "degradation in endoplasmic reticulum protein 1 (human)" EXACT [UniProtKB:Q9BUN8]
xref: UniProtKB:Q9BUN8
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006422 ! derlin-1
relationship: has_gene_template HGNC:28454 ! DERL1 (human)

[Term]
id: PR:000042893
name: derlin-1 isoform 1
def: "A derlin-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BUN8-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "DERL1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000006422 ! derlin-1

[Term]
id: PR:Q9VQ57
name: derlin-1 (fruit fly)
def: "A derlin-1 that is encoded in the genome of fruit fly." [OMA:Q9VQ57, PRO:DNx]
comment: Category=organism-gene.
synonym: "Der-1" RELATED Gene-based [UniProtKB:Q9VQ57]
synonym: "CG10908" RELATED Gene-based [UniProtKB:Q9VQ57]
synonym: "fly-DERL1" EXACT PRO-short-label [PRO:DNx]
synonym: "DER1-like protein 1 (fruit fly)" EXACT [UniProtKB:Q9VQ57]
xref: UniProtKB:Q9VQ57
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000006422 ! derlin-1
relationship: has_gene_template FlyBase:FBgn0267972 ! Der-1 (fruit fly)

[Term]
id: PR:000006422
name: derlin-1
def: "A protein that is a translation product of the human DERL1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "DER1" RELATED Gene-based []
synonym: "DERL1" EXACT PRO-short-label [PRO:DNx]
synonym: "DERtrin-1" EXACT []
synonym: "UNQ243/PRO276" RELATED Gene-based []
synonym: "der1-like protein 1" EXACT []
synonym: "degradation in endoplasmic reticulum protein 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000047169
name: derlin-1, initiator methionine removed form (human)
def: "A derlin-1 (human) that has had the initiator methionine removed. UniProtKB:Q9BUN8, 2-251." [PRO:DNx, Reactome:R-HSA-6781898]
comment: Category=organism-modification.
synonym: "PRO_0000219042" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hDERL1/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9BUN8, 2-251" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-6781898 "PR:000047169 located_in GO:0005789"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:Q9BUN8 ! derlin-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q54IC9
name: probable derlin-1 homolog (Dictyostelium discoideum)
def: "A derlin-1 that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54IC9, PRO:DNx]
comment: Category=organism-gene.
synonym: "derl1" RELATED Gene-based [UniProtKB:Q54IC9]
synonym: "Dicty-DERL1" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0288833" RELATED Gene-based [UniProtKB:Q54IC9]
xref: UniProtKB:Q54IC9
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000006422 ! derlin-1
relationship: has_gene_template dictyBase:DDB_G0288833 ! derl1 (Dictyostelium discoideum)

[Term]
id: PR:Q99J56
name: derlin-1 (mouse)
def: "A derlin-1 that is encoded in the genome of mouse." [OMA:Q99J56, PRO:DNx]
comment: Category=organism-gene.
synonym: "Der1" RELATED Gene-based [UniProtKB:Q99J56]
synonym: "Derl1" RELATED Gene-based [UniProtKB:Q99J56]
synonym: "mDERL1" EXACT PRO-short-label [PRO:DNx]
synonym: "Der1-like protein 1 (mouse)" EXACT [UniProtKB:Q99J56]
synonym: "degradation in endoplasmic reticulum protein 1 (mouse)" EXACT [UniProtKB:Q99J56]
xref: UniProtKB:Q99J56
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000006422 ! derlin-1
relationship: has_gene_template MGI:1915069 ! Derl1 (mouse)

[Term]
id: PR:Q93561
name: derlin-1 (worm)
def: "A derlin-1 that is encoded in the genome of worm." [OMA:Q93561, PRO:DNx]
comment: Category=organism-gene.
synonym: "cup-2" RELATED Gene-based [UniProtKB:Q93561]
synonym: "der-1" RELATED Gene-based [UniProtKB:Q93561]
synonym: "F25D7.1" RELATED Gene-based [UniProtKB:Q93561]
synonym: "DERL1 (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "cDerlin-1 (worm)" EXACT [UniProtKB:Q93561]
synonym: "DER1-like protein 1 (worm)" EXACT [UniProtKB:Q93561]
synonym: "coelomocyte uptake defective protein 2 (worm)" EXACT [UniProtKB:Q93561]
xref: UniProtKB:Q93561
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000006422 ! derlin-1
relationship: has_gene_template WormBase:WBGene00000843 ! cup-2 (worm)

[Term]
id: PR:Q99J56-1
name: derlin-1 isoform 1 (mouse)
def: "A derlin-1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mDERL1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q99J56-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000042893 ! derlin-1 isoform 1

[Term]
id: PR:Q9BUN8-2
name: derlin-1 isoform h2 (human)
def: "A derlin-1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9BUN8-2." [PRO:DNx, UniProtKB:Q9BUN8]
comment: Category=organism-sequence.
synonym: "hDERL1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9BUN8-2
is_a: PR:Q9BUN8 ! derlin-1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9BUN8-1
name: derlin-1 isoform 1 (human)
def: "A derlin-1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hDERL1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9BUN8-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000042893 ! derlin-1 isoform 1