[Term]
id: PR:Q94515
name: sphingolipid Delta(4)-desaturase DES1 (fruit fly)
def: "A sphingolipid Delta(4)-desaturase DES1 that is encoded in the genome of fruit fly." [PRO:DNx]
comment: Category=organism-gene.
synonym: "ifc" RELATED Gene-based [UniProtKB:Q94515]
synonym: "CG9078" RELATED Gene-based [UniProtKB:Q94515]
synonym: "fly-DEGS1" EXACT PRO-short-label [PRO:DNx]
synonym: "DES-1 (fruit fly)" EXACT [UniProtKB:Q94515]
synonym: "dihydroceramide desaturase-1 (fruit fly)" EXACT [UniProtKB:Q94515]
synonym: "degenerative spermatocyte homolog 1 (fruit fly)" EXACT [UniProtKB:Q94515]
xref: UniProtKB:Q94515
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000006413 ! sphingolipid Delta(4)-desaturase DES1
relationship: has_gene_template FlyBase:FBgn0001941 ! ifc (fruit fly)

[Term]
id: PR:000006413
name: sphingolipid Delta(4)-desaturase DES1
def: "A protein that is a translation product of the human DEGS1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "MLD" RELATED Gene-based []
synonym: "DES1" RELATED Gene-based []
synonym: "Degs" RELATED Gene-based []
synonym: "Mdes" RELATED Gene-based []
synonym: "DEGS1" EXACT PRO-short-label [PRO:DNx]
synonym: "MIG15" RELATED Gene-based []
synonym: "membrane lipid desaturase" EXACT []
synonym: "dihydroceramide desaturase-1" EXACT []
synonym: "degenerative spermatocyte homolog 1" EXACT []
synonym: "cell migration-inducing gene 15 protein" EXACT []
xref: IUPHARobj:2484
is_a: PR:000000001 ! protein

[Term]
id: PR:000047167
name: sphingolipid Delta(4)-desaturase DES1, initiator methionine removed form (human)
def: "A sphingolipid Delta(4)-desaturase DES1 (human) that has had the initiator methionine removed. UniProtKB:O15121, 2-323." [PRO:DNx, Reactome:R-HSA-428201]
comment: Category=organism-modification.
synonym: "PRO_0000312727" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hDEGS1/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O15121, 2-323" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-428201 "PR:000047167 located_in GO:0005789"
xref: Reactome:R-HSA-6799512 "PR:000047167 located_in GO:0035579"
xref: Reactome:R-HSA-6806305 "PR:000047167 located_in GO:0005886"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:O15121 ! sphingolipid Delta(4)-desaturase DES1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q5F3C1-1
name: sphingolipid Delta(4)-desaturase DES1 isoform 1 (chicken)
def: "A sphingolipid Delta(4)-desaturase DES1 isoform 1 that is encoded in the genome of chicken." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "chick-DEGS1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q5F3C1-1
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000038040 ! sphingolipid Delta(4)-desaturase DES1 isoform 1

[Term]
id: PR:O15121-1
name: sphingolipid Delta(4)-desaturase DES1 isoform 1 (human)
def: "A sphingolipid Delta(4)-desaturase DES1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hDEGS1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O15121-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038040 ! sphingolipid Delta(4)-desaturase DES1 isoform 1

[Term]
id: PR:Q5XIF5
name: sphingolipid Delta(4)-desaturase DES1 (rat)
def: "A sphingolipid Delta(4)-desaturase DES1 that is encoded in the genome of rat." [OMA:Q5XIF5, PANTHER:PTHR12879:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Degs" RELATED Gene-based [UniProtKB:Q5XIF5]
synonym: "Des1" RELATED Gene-based [UniProtKB:Q5XIF5]
synonym: "Degs1" RELATED Gene-based [UniProtKB:Q5XIF5]
synonym: "rDEGS1" EXACT PRO-short-label [PRO:DNx]
synonym: "retinol isomerase (rat)" RELATED [UniProtKB:Q5XIF5]
synonym: "dihydroceramide desaturase-1 (rat)" EXACT [UniProtKB:Q5XIF5]
synonym: "degenerative spermatocyte homolog 1 (rat)" EXACT [UniProtKB:Q5XIF5]
synonym: "degenerative spermatocyte-like protein RDES (rat)" EXACT [UniProtKB:Q5XIF5]
xref: UniProtKB:Q5XIF5
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000006413 ! sphingolipid Delta(4)-desaturase DES1
relationship: has_gene_template RGD:70917 ! Degs1 (rat)

[Term]
id: PR:O09005
name: sphingolipid Delta(4)-desaturase DES1 (mouse)
def: "A sphingolipid Delta(4)-desaturase DES1 that is encoded in the genome of mouse." [OMA:O09005, PRO:DNx]
comment: Category=organism-gene.
synonym: "Degs" RELATED Gene-based [UniProtKB:O09005]
synonym: "Des1" RELATED Gene-based [UniProtKB:O09005]
synonym: "Mdes" RELATED Gene-based [UniProtKB:O09005]
synonym: "Degs1" RELATED Gene-based [UniProtKB:O09005]
synonym: "mDEGS1" EXACT PRO-short-label [PRO:DNx]
synonym: "retinol isomerase (mouse)" RELATED [UniProtKB:O09005]
synonym: "dihydroceramide desaturase-1 (mouse)" EXACT [UniProtKB:O09005]
synonym: "degenerative spermatocyte homolog 1 (mouse)" EXACT [UniProtKB:O09005]
xref: UniProtKB:O09005
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000006413 ! sphingolipid Delta(4)-desaturase DES1
relationship: has_gene_template MGI:1097711 ! Degs1 (mouse)

[Term]
id: PR:000038040
name: sphingolipid Delta(4)-desaturase DES1 isoform 1
def: "A sphingolipid Delta(4)-desaturase DES1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15121-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "DEGS1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000006413 ! sphingolipid Delta(4)-desaturase DES1

[Term]
id: PR:O15121
name: sphingolipid Delta(4)-desaturase DES1 (human)
def: "A sphingolipid Delta(4)-desaturase DES1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O15121]
comment: Category=organism-gene.
synonym: "MLD" RELATED Gene-based [UniProtKB:O15121]
synonym: "DES1" RELATED Gene-based [UniProtKB:O15121]
synonym: "DEGS1" RELATED Gene-based [UniProtKB:O15121]
synonym: "MIG15" RELATED Gene-based [UniProtKB:O15121]
synonym: "hDEGS1" EXACT PRO-short-label [PRO:DNx]
synonym: "retinol isomerase (human)" RELATED [UniProtKB:O15121]
synonym: "membrane lipid desaturase (human)" EXACT [UniProtKB:O15121]
synonym: "dihydroceramide desaturase-1 (human)" EXACT [UniProtKB:O15121]
synonym: "degenerative spermatocyte homolog 1 (human)" EXACT [UniProtKB:O15121]
synonym: "cell migration-inducing gene 15 protein (human)" EXACT [UniProtKB:O15121]
xref: UniProtKB:O15121
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006413 ! sphingolipid Delta(4)-desaturase DES1
relationship: has_gene_template HGNC:13709 ! DEGS1 (human)

[Term]
id: PR:Q5F3C1
name: sphingolipid Delta(4)-desaturase DES1 (chicken)
def: "A sphingolipid Delta(4)-desaturase DES1 that is encoded in the genome of chicken." [OMA:Q5F3C1, PANTHER:PTHR12879:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "DES1" RELATED Gene-based [UniProtKB:Q5F3C1]
synonym: "DEGS1" RELATED Gene-based [UniProtKB:Q5F3C1]
synonym: "chick-DEGS1" EXACT PRO-short-label [PRO:DNx]
synonym: "RCJMB04_22e12" RELATED Gene-based [UniProtKB:Q5F3C1]
synonym: "retinol isomerase (chicken)" RELATED [UniProtKB:Q5F3C1]
synonym: "dihydroceramide desaturase-1 (chicken)" EXACT [UniProtKB:Q5F3C1]
synonym: "degenerative spermatocyte homolog 1 (chicken)" EXACT [UniProtKB:Q5F3C1]
xref: UniProtKB:Q5F3C1
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000006413 ! sphingolipid Delta(4)-desaturase DES1
relationship: has_gene_template NCBIGene:421327 ! DEGS1 (chicken)

[Term]
id: PR:Q5XIF5-1
name: sphingolipid Delta(4)-desaturase DES1 isoform 1 (rat)
def: "A sphingolipid Delta(4)-desaturase DES1 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rDEGS1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q5XIF5-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000038040 ! sphingolipid Delta(4)-desaturase DES1 isoform 1

[Term]
id: PR:O09005-1
name: sphingolipid Delta(4)-desaturase DES1 isoform 1 (mouse)
def: "A sphingolipid Delta(4)-desaturase DES1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mDEGS1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O09005-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000038040 ! sphingolipid Delta(4)-desaturase DES1 isoform 1