[Term]
id: PR:P35638-1
name: DNA damage-inducible transcript 3 protein isoform 1 (human)
def: "A DNA damage-inducible transcript 3 protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35638-1." [PRO:DNx, UniProtKB:P35638]
comment: Category=organism-sequence. Requested by=PubChem.
synonym: "hDDIT3/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P35638-1
is_a: PR:P35638 ! DNA damage-inducible transcript 3 protein (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P35639-1
name: DNA damage-inducible transcript 3 protein isoform m1 (mouse)
def: "A DNA damage-inducible transcript 3 protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35639-1." [PMID:22242125, PRO:HJD]
comment: Category=organism-sequence. Evidence=(ECO:0000006, based on PMID:22242125). Note: DNA damage-inducible transcript 3 protein (mouse) isoform m2 (PR:A0A2R8VHR8-1) is entirely encoded within the 5'UTR of isoform m1 (this class), and therefore shares no sequence similarity with the latter.
synonym: "mDDIT3/iso:m1" EXACT PRO-short-label [PRO:KER]
xref: UniProtKB:P35639-1
is_a: PR:P35639 ! DNA damage-inducible transcript 3 protein (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000006347
name: DNA damage-inducible transcript 3 protein
def: "A protein that is a translation product of the human DDIT3 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "CHOP" EXACT []
synonym: "DDIT3" EXACT PRO-short-label [PRO:DNx]
synonym: "DDIT-3" EXACT []
synonym: "GADD153" RELATED []
synonym: "C/EBP-homologous protein" EXACT []
synonym: "DNA damage-inducible transcript 3" EXACT []
synonym: "growth arrest and DNA damage-inducible protein GADD153" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q62857
name: DNA damage-inducible transcript 3 protein (rat)
def: "A DNA damage-inducible transcript 3 protein that is encoded in the genome of rat." [PANTHER:PTHR16833:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Chop" RELATED Gene-based [UniProtKB:Q62857]
synonym: "Ddit3" RELATED Gene-based [UniProtKB:Q62857]
synonym: "Chop10" RELATED Gene-based [UniProtKB:Q62857]
synonym: "rDDIT3" EXACT PRO-short-label [PRO:DNx]
synonym: "Gadd153" RELATED Gene-based [UniProtKB:Q62857]
synonym: "CHOP (rat)" EXACT [UniProtKB:Q62857]
synonym: "DDIT-3 (rat)" EXACT [UniProtKB:Q62857]
synonym: "CHOP-10 (rat)" EXACT [UniProtKB:Q62857]
synonym: "C/EBP zeta (rat)" EXACT [UniProtKB:Q62857]
synonym: "C/EBP-homologous protein (rat)" EXACT [UniProtKB:Q62857]
synonym: "C/EBP-homologous protein 10 (rat)" EXACT [UniProtKB:Q62857]
synonym: "CCAAT/enhancer-binding protein homologous protein (rat)" EXACT [UniProtKB:Q62857]
synonym: "growth arrest and DNA-damage-inducible protein GADD153 (rat)" EXACT [UniProtKB:Q62857]
xref: UniProtKB:Q62857
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000006347 ! DNA damage-inducible transcript 3 protein
relationship: has_gene_template RGD:62391 ! Ddit3 (rat)

[Term]
id: PR:P35638
name: DNA damage-inducible transcript 3 protein (human)
def: "A DNA damage-inducible transcript 3 protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:P35638]
comment: Category=organism-gene.
synonym: "hDDIT3" EXACT PRO-short-label [PRO:DNx]
xref: Reactome:R-HSA-381110 "PR:P35638 located_in GO:0005654"
xref: UniProtKB:P35638
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006347 ! DNA damage-inducible transcript 3 protein
relationship: has_gene_template HGNC:2726 ! DDIT3 (human)

[Term]
id: PR:P35639
name: DNA damage-inducible transcript 3 protein (mouse)
def: "A DNA damage-inducible transcript 3 protein that is encoded in the genome of mouse." [OMA:P35639, PRO:DNx]
comment: Category=organism-gene. Requested by=PubChem.
synonym: "Chop" RELATED Gene-based [UniProtKB:P35639]
synonym: "Ddit3" RELATED Gene-based [UniProtKB:P35639]
synonym: "Chop10" RELATED Gene-based [UniProtKB:P35639]
synonym: "mDDIT3" EXACT PRO-short-label [PRO:DNx]
synonym: "Gadd153" RELATED Gene-based [UniProtKB:P35639]
synonym: "CHOP (mouse)" EXACT [UniProtKB:P35639]
synonym: "DDIT-3 (mouse)" EXACT [UniProtKB:P35639]
synonym: "CHOP-10 (mouse)" EXACT [UniProtKB:P35639]
synonym: "C/EBP zeta (mouse)" EXACT [UniProtKB:P35639]
synonym: "C/EBP-homologous protein (mouse)" EXACT [UniProtKB:P35639]
synonym: "C/EBP-homologous protein 10 (mouse)" EXACT [UniProtKB:P35639]
synonym: "CCAAT/enhancer-binding protein homologous protein (mouse)" EXACT [UniProtKB:P35639]
synonym: "growth arrest and DNA-damage-inducible protein GADD153 (mouse)" EXACT [UniProtKB:P35639]
xref: UniProtKB:P35639
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000006347 ! DNA damage-inducible transcript 3 protein
relationship: has_gene_template MGI:109247 ! Ddit3 (mouse)

[Term]
id: PR:A0A2R8VHR8-1
name: DNA damage-inducible transcript 3 protein isoform m2 (mouse)
def: "A DNA damage-inducible transcript 3 protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A0A2R8VHR8-1." [PMID:21285359, PRO:HJD]
comment: Category=organism-sequence. Evidence=(ECO:0000006, based on PMID:21285359). Note: DNA damage-inducible transcript 3 protein (mouse) isoform m2 (this class) is entirely encoded within the 5'UTR of isoform m1 (PR:P35639-1), and therefore shares no sequence similarity with the latter.
synonym: "AltDDIT2" EXACT [PRO:KER]
synonym: "mDDIT3/iso:m2" EXACT PRO-short-label [PRO:KER]
synonym: "DDIT3 upstream open reading frame protein" EXACT [PRO:KER]
xref: UniProtKB:A0A2R8VHR8-1
is_a: PR:P35639 ! DNA damage-inducible transcript 3 protein (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus