[Term]
id: PR:Q9NPI6
name: mRNA-decapping enzyme 1A (human)
def: "An mRNA-decapping enzyme 1A that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9NPI6]
comment: Category=organism-gene.
synonym: "SMIF" RELATED Gene-based [UniProtKB:Q9NPI6]
synonym: "DCP1A" RELATED Gene-based [UniProtKB:Q9NPI6]
synonym: "hDCP1A" EXACT PRO-short-label [PRO:DNx]
synonym: "transcription factor SMIF (human)" EXACT [UniProtKB:Q9NPI6]
synonym: "Smad4-interacting transcriptional co-activator (human)" EXACT [UniProtKB:Q9NPI6]
xref: UniProtKB:Q9NPI6
xref: Reactome:R-HSA-430043 "PR:Q9NPI6 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006317 ! mRNA-decapping enzyme 1A
relationship: has_gene_template HGNC:18714 ! DCP1A (human)

[Term]
id: PR:000006317
name: mRNA-decapping enzyme 1A
def: "A protein that is a translation product of the human DCP1A gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "SMIF" RELATED Gene-based []
synonym: "DCP1A" EXACT PRO-short-label [PRO:DNx]
synonym: "Mitc1" RELATED Gene-based []
synonym: "transcription factor SMIF" EXACT []
synonym: "smad4-interacting transcriptional co-activator" EXACT []
synonym: "MAD homolog 4-interacting transcription coactivator 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q9NPI6-2
name: mRNA-decapping enzyme 1A isoform h2 (human)
def: "An mRNA-decapping enzyme 1A (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NPI6-2." [PRO:DNx, UniProtKB:Q9NPI6]
comment: Category=organism-sequence.
synonym: "hDCP1A/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9NPI6-2
is_a: PR:Q9NPI6 ! mRNA-decapping enzyme 1A (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046068
name: mRNA-decapping enzyme 1A phosphorylated 1 (human)
def: "An mRNA-decapping enzyme 1A (human) that has been phosphorylated at the position equivalent to Ser-315 of the amino acid sequence represented by UniProtKB:Q9NPI6-1. Example: UniProtKB:Q9NPI6-1, Ser-315, MOD:00046." [PMID:21859862, iPTMnet:Q9NPI6]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:21859862). Status=unreviewed.
synonym: "hDCP1A/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9NPI6-1, Ser-315, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9NPI6 ! mRNA-decapping enzyme 1A (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9NPI6-1
name: mRNA-decapping enzyme 1A isoform h1 (human)
def: "An mRNA-decapping enzyme 1A (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NPI6-1." [PRO:DNx, UniProtKB:Q9NPI6]
comment: Category=organism-sequence.
synonym: "hDCP1A/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9NPI6-1
is_a: PR:Q9NPI6 ! mRNA-decapping enzyme 1A (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens