[Term]
id: PR:000006147
name: lanosterol 14-alpha demethylase
def: "A protein that is a translation product of the human CYP51A1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "LDM" EXACT []
synonym: "CYP51" RELATED Gene-based []
synonym: "CYPLI" EXACT []
synonym: "CYP51A1" EXACT PRO-short-label [PRO:DNx]
synonym: "cytochrome P450LI" EXACT []
synonym: "cytochrome P45014DM" EXACT []
synonym: "cytochrome P450 51A1" EXACT []
synonym: "cytochrome P450-14DM" EXACT []
synonym: "sterol 14-alpha demethylase" EXACT []
xref: IUPHARobj:1374
is_a: PR:000000001 ! protein

[Term]
id: PR:Q16850
name: lanosterol 14-alpha demethylase (human)
def: "A lanosterol 14-alpha demethylase that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q16850]
comment: Category=organism-gene.
synonym: "CYP51" RELATED Gene-based [UniProtKB:Q16850]
synonym: "CYP51A1" RELATED Gene-based [UniProtKB:Q16850]
synonym: "hCYP51A1" EXACT PRO-short-label [PRO:DNx]
synonym: "LDM (human)" EXACT [UniProtKB:Q16850]
synonym: "CYPLI (human)" EXACT [UniProtKB:Q16850]
synonym: "cytochrome P450LI (human)" EXACT [UniProtKB:Q16850]
synonym: "cytochrome P45014DM (human)" EXACT [UniProtKB:Q16850]
synonym: "cytochrome P450 51A1 (human)" EXACT [UniProtKB:Q16850]
synonym: "cytochrome P450-14DM (human)" EXACT [UniProtKB:Q16850]
synonym: "sterol 14-alpha demethylase (human)" EXACT [UniProtKB:Q16850]
xref: Reactome:R-HSA-194721 "PR:Q16850 located_in GO:0005789"
xref: UniProtKB:Q16850
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006147 ! lanosterol 14-alpha demethylase
relationship: has_gene_template HGNC:2649 ! CYP51A1 (human)

[Term]
id: PR:Q16850-2
name: lanosterol 14-alpha demethylase isoform h2 (human)
def: "A lanosterol 14-alpha demethylase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16850-2." [PRO:DNx, UniProtKB:Q16850]
comment: Category=organism-sequence.
synonym: "hCYP51A1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q16850-2
is_a: PR:Q16850 ! lanosterol 14-alpha demethylase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q16850-1
name: lanosterol 14-alpha demethylase isoform 1 (human)
def: "A lanosterol 14-alpha demethylase isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hCYP51A1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q16850-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040749 ! lanosterol 14-alpha demethylase isoform 1