[Term]
id: PR:Q9WVK8
name: cholesterol 24-hydroxylase (mouse)
def: "A cytochrome P450 46A1 that is encoded in the genome of mouse." [OMA:Q9WVK8, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cyp46" RELATED Gene-based [UniProtKB:Q9WVK8]
synonym: "Cyp46a1" RELATED Gene-based [UniProtKB:Q9WVK8]
synonym: "mCYP46A1" EXACT PRO-short-label [PRO:DNx]
synonym: "CH24H (mouse)" EXACT [UniProtKB:Q9WVK8]
synonym: "cytochrome P450 46A1 (mouse)" EXACT [UniProtKB:Q9WVK8]
synonym: "cholesterol 24S-hydroxylase (mouse)" EXACT [UniProtKB:Q9WVK8]
synonym: "cholesterol 24-monooxygenase (mouse)" EXACT [UniProtKB:Q9WVK8]
xref: UniProtKB:Q9WVK8
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000006134 ! cytochrome P450 46A1
relationship: has_gene_template MGI:1341877 ! Cyp46a1 (mouse)

[Term]
id: PR:Q9SMP5
name: cytochrome P450 94B3 (Arabidopsis thaliana)
def: "A cytochrome P450 46A1 that is encoded in the genome of Arabidopsis thaliana." [PRO:DNx]
comment: Category=organism-gene.
synonym: "CYP94B3" RELATED Gene-based [UniProtKB:Q9SMP5]
synonym: "T8P19.30" RELATED Gene-based [UniProtKB:Q9SMP5]
synonym: "At3g48520" RELATED Gene-based [UniProtKB:Q9SMP5]
synonym: "At-CYP46A1" EXACT PRO-short-label [PRO:DNx]
synonym: "jasmonoyl-isoleucine-12-hydroxylase (Arabidopsis thaliana)" EXACT [UniProtKB:Q9SMP5]
synonym: "jasmonoyl-L-amino acid 12-hydroxylase (Arabidopsis thaliana)" EXACT [UniProtKB:Q9SMP5]
xref: UniProtKB:Q9SMP5
intersection_of: only_in_taxon NCBITaxon:3702 ! Arabidopsis thaliana
intersection_of: PR:000006134 ! cytochrome P450 46A1
relationship: has_gene_template Araport:AT3G48520 ! CYP94B3 (Arabidopsis thaliana)

[Term]
id: PR:Q9WVK8-1
name: cholesterol 24-hydroxylase isoform 1 (mouse)
def: "A cytochrome P450 46A1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mCYP46A1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9WVK8-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000044286 ! cytochrome P450 46A1 isoform 1

[Term]
id: PR:Q9Y6A2
name: cholesterol 24-hydroxylase (human)
def: "A cytochrome P450 46A1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9Y6A2]
comment: Category=organism-gene.
synonym: "CYP46" RELATED Gene-based [UniProtKB:Q9Y6A2]
synonym: "CYP46A1" RELATED Gene-based [UniProtKB:Q9Y6A2]
synonym: "hCYP46A1" EXACT PRO-short-label [PRO:DNx]
synonym: "CH24H (human)" EXACT [UniProtKB:Q9Y6A2]
synonym: "cytochrome P450 46A1 (human)" EXACT [UniProtKB:Q9Y6A2]
synonym: "cholesterol 24S-hydroxylase (human)" EXACT [UniProtKB:Q9Y6A2]
synonym: "cholesterol 24-monooxygenase (human)" EXACT [UniProtKB:Q9Y6A2]
xref: UniProtKB:Q9Y6A2
xref: Reactome:R-HSA-192202 "PR:Q9Y6A2 located_in GO:0005789"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006134 ! cytochrome P450 46A1
relationship: has_gene_template HGNC:2641 ! CYP46A1 (human)

[Term]
id: PR:Q9Y6A2-2
name: cholesterol 24-hydroxylase isoform h2 (human)
def: "A cholesterol 24-hydroxylase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y6A2-2." [PRO:DNx, UniProtKB:Q9Y6A2]
comment: Category=organism-sequence.
synonym: "hCYP46A1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Y6A2-2
is_a: PR:Q9Y6A2 ! cholesterol 24-hydroxylase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000044286
name: cytochrome P450 46A1 isoform 1
def: "A cytochrome P450 46A1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y6A2-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "CYP46A1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000006134 ! cytochrome P450 46A1

[Term]
id: PR:Q9Y6A2-3
name: cholesterol 24-hydroxylase isoform h3 (human)
def: "A cholesterol 24-hydroxylase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y6A2-3." [PRO:DNx, UniProtKB:Q9Y6A2]
comment: Category=organism-sequence.
synonym: "hCYP46A1/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Y6A2-3
is_a: PR:Q9Y6A2 ! cholesterol 24-hydroxylase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9Y6A2-1
name: cholesterol 24-hydroxylase isoform 1 (human)
def: "A cytochrome P450 46A1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hCYP46A1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9Y6A2-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000044286 ! cytochrome P450 46A1 isoform 1

[Term]
id: PR:000006134
name: cytochrome P450 46A1
def: "A protein that is a translation product of the human CYP46A1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "CH24H" EXACT []
synonym: "CYP46" RELATED Gene-based []
synonym: "CYP46A1" EXACT PRO-short-label [PRO:DNx]
synonym: "cholesterol 24S-hydroxylase" EXACT []
synonym: "cholesterol 24-monooxygenase" EXACT []
xref: IUPHARobj:1373
is_a: PR:000000001 ! protein