[Term]
id: PR:P05093
name: steroid 17-alpha-hydroxylase/17,20 lyase (human)
def: "A cytochrome P450 17A1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P05093]
comment: Category=organism-gene.
synonym: "CYP17" RELATED Gene-based [UniProtKB:P05093]
synonym: "S17AH" RELATED Gene-based [UniProtKB:P05093]
synonym: "CYP17A1" RELATED Gene-based [UniProtKB:P05093]
synonym: "hCYP17A1" EXACT PRO-short-label [PRO:DNx]
synonym: "CYPXVII (human)" EXACT [UniProtKB:P05093]
synonym: "cytochrome P450c17 (human)" EXACT [UniProtKB:P05093]
synonym: "cytochrome P450-C17 (human)" EXACT [UniProtKB:P05093]
synonym: "cytochrome P450 17A1 (human)" EXACT [UniProtKB:P05093]
synonym: "steroid 17-alpha-monooxygenase (human)" EXACT [UniProtKB:P05093]
synonym: "17-alpha-hydroxyprogesterone aldolase (human)" EXACT [UniProtKB:P05093]
xref: Reactome:R-HSA-193119 "PR:P05093 located_in GO:0005789"
xref: UniProtKB:P05093
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006099 ! cytochrome P450 17A1
relationship: has_gene_template HGNC:2593 ! CYP17A1 (human)

[Term]
id: PR:000006099
name: cytochrome P450 17A1
def: "A protein that is a translation product of the human CYP17A1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "CYP17" RELATED Gene-based []
synonym: "S17AH" RELATED Gene-based []
synonym: "CYP17A1" EXACT PRO-short-label [PRO:DNx]
synonym: "CYPXVII" EXACT []
synonym: "cytochrome P450c17" EXACT []
synonym: "cytochrome P450-C17" EXACT []
synonym: "steroid 17-alpha-monooxygenase" EXACT []
synonym: "17-alpha-hydroxyprogesterone aldolase" EXACT []
xref: IUPHARobj:1361
is_a: PR:000000001 ! protein

[Term]
id: PR:000045639
name: steroid 17-alpha-hydroxylase/17,20 lyase phosphorylated 1 (human)
def: "A steroid 17-alpha-hydroxylase/17,20 lyase (human) that has been phosphorylated at Ser-258. UniProtKB:P05093, Ser-258, MOD:00046." [PMID:20160131, iPTMnet:P05093]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:20160131). Status=unreviewed.
synonym: "hCYP17A1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P05093, Ser-258, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P05093 ! steroid 17-alpha-hydroxylase/17,20 lyase (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens