[Term]
id: PR:P11715
name: steroid 17-alpha-hydroxylase/17,20 lyase (rat)
def: "A cytochrome P450 17A1 that is encoded in the genome of rat." [OMA:P11715, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cyp17" RELATED Gene-based [UniProtKB:P11715]
synonym: "Cyp17a1" RELATED Gene-based [UniProtKB:P11715]
synonym: "rCYP17A1" EXACT PRO-short-label [PRO:DNx]
synonym: "CYPXVII (rat)" EXACT [UniProtKB:P11715]
synonym: "cytochrome P450c17 (rat)" EXACT [UniProtKB:P11715]
synonym: "cytochrome P450-C17 (rat)" EXACT [UniProtKB:P11715]
synonym: "cytochrome P450 17A1 (rat)" EXACT [UniProtKB:P11715]
synonym: "steroid 17-alpha-monooxygenase (rat)" EXACT [UniProtKB:P11715]
synonym: "17-alpha-hydroxyprogesterone aldolase (rat)" EXACT [UniProtKB:P11715]
xref: UniProtKB:P11715
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000006099 ! cytochrome P450 17A1
relationship: has_gene_template RGD:2456 ! Cyp17a1 (rat)

[Term]
id: PR:P27786
name: steroid 17-alpha-hydroxylase/17,20 lyase (mouse)
def: "A cytochrome P450 17A1 that is encoded in the genome of mouse." [OMA:P27786, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cyp17" RELATED Gene-based [UniProtKB:P27786]
synonym: "Cyp17a1" RELATED Gene-based [UniProtKB:P27786]
synonym: "mCYP17A1" EXACT PRO-short-label [PRO:DNx]
synonym: "CYPXVII (mouse)" EXACT [UniProtKB:P27786]
synonym: "cytochrome P450c17 (mouse)" EXACT [UniProtKB:P27786]
synonym: "cytochrome P450-C17 (mouse)" EXACT [UniProtKB:P27786]
synonym: "cytochrome P450 17A1 (mouse)" EXACT [UniProtKB:P27786]
synonym: "steroid 17-alpha-monooxygenase (mouse)" EXACT [UniProtKB:P27786]
synonym: "17-alpha-hydroxyprogesterone aldolase (mouse)" EXACT [UniProtKB:P27786]
xref: UniProtKB:P27786
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000006099 ! cytochrome P450 17A1
relationship: has_gene_template MGI:88586 ! Cyp17a1 (mouse)

[Term]
id: PR:000039179
name: cytochrome P450 17A1 isoform 1
def: "A cytochrome P450 17A1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27786-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "CYP17A1/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000006099 ! cytochrome P450 17A1

[Term]
id: PR:000045639
name: steroid 17-alpha-hydroxylase/17,20 lyase phosphorylated 1 (human)
def: "A steroid 17-alpha-hydroxylase/17,20 lyase (human) that has been phosphorylated at Ser-258. UniProtKB:P05093, Ser-258, MOD:00046." [PMID:20160131, iPTMnet:P05093]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:20160131). Status=unreviewed.
synonym: "hCYP17A1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P05093, Ser-258, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P05093 ! steroid 17-alpha-hydroxylase/17,20 lyase (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P12394
name: steroid 17-alpha-hydroxylase/17,20 lyase (chicken)
def: "A cytochrome P450 17A1 that is encoded in the genome of chicken." [OMA:P12394, PRO:DNx]
comment: Category=organism-gene.
synonym: "CYP17" RELATED Gene-based [UniProtKB:P12394]
synonym: "CYP17A1" RELATED Gene-based [UniProtKB:P12394]
synonym: "chick-CYP17A1" EXACT PRO-short-label [PRO:DNx]
synonym: "CYPXVII (chicken)" EXACT [UniProtKB:P12394]
synonym: "cytochrome P450c17 (chicken)" EXACT [UniProtKB:P12394]
synonym: "cytochrome P450-C17 (chicken)" EXACT [UniProtKB:P12394]
synonym: "cytochrome P450 17A1 (chicken)" EXACT [UniProtKB:P12394]
synonym: "17-alpha-hydroxyprogesterone aldolase (chicken)" EXACT [UniProtKB:P12394]
xref: UniProtKB:P12394
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000006099 ! cytochrome P450 17A1
relationship: has_gene_template CGNC:52327 ! CYP17A1 (chicken)

[Term]
id: PR:P11715-1
name: steroid 17-alpha-hydroxylase/17,20 lyase isoform 1 (rat)
def: "A cytochrome P450 17A1 isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rCYP17A1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P11715-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000039179 ! cytochrome P450 17A1 isoform 1

[Term]
id: PR:P27786-1
name: steroid 17-alpha-hydroxylase/17,20 lyase isoform 1 (mouse)
def: "A cytochrome P450 17A1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mCYP17A1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P27786-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039179 ! cytochrome P450 17A1 isoform 1

[Term]
id: PR:000006099
name: cytochrome P450 17A1
def: "A protein that is a translation product of the human CYP17A1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "CYP17" RELATED Gene-based []
synonym: "S17AH" RELATED Gene-based []
synonym: "CYP17A1" EXACT PRO-short-label [PRO:DNx]
synonym: "CYPXVII" EXACT []
synonym: "cytochrome P450c17" EXACT []
synonym: "cytochrome P450-C17" EXACT []
synonym: "steroid 17-alpha-monooxygenase" EXACT []
synonym: "17-alpha-hydroxyprogesterone aldolase" EXACT []
xref: IUPHARobj:1361
is_a: PR:000000001 ! protein

[Term]
id: PR:P05093
name: steroid 17-alpha-hydroxylase/17,20 lyase (human)
def: "A cytochrome P450 17A1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P05093]
comment: Category=organism-gene.
synonym: "CYP17" RELATED Gene-based [UniProtKB:P05093]
synonym: "S17AH" RELATED Gene-based [UniProtKB:P05093]
synonym: "CYP17A1" RELATED Gene-based [UniProtKB:P05093]
synonym: "hCYP17A1" EXACT PRO-short-label [PRO:DNx]
synonym: "CYPXVII (human)" EXACT [UniProtKB:P05093]
synonym: "cytochrome P450c17 (human)" EXACT [UniProtKB:P05093]
synonym: "cytochrome P450-C17 (human)" EXACT [UniProtKB:P05093]
synonym: "cytochrome P450 17A1 (human)" EXACT [UniProtKB:P05093]
synonym: "steroid 17-alpha-monooxygenase (human)" EXACT [UniProtKB:P05093]
synonym: "17-alpha-hydroxyprogesterone aldolase (human)" EXACT [UniProtKB:P05093]
xref: Reactome:R-HSA-193119 "PR:P05093 located_in GO:0005789"
xref: UniProtKB:P05093
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006099 ! cytochrome P450 17A1
relationship: has_gene_template HGNC:2593 ! CYP17A1 (human)