[Term] id: PR:O70244-1 name: cubilin isoform 1 (rat) def: "A cubilin isoform 1 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rCUBN/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O70244-1 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000043440 ! cubilin isoform 1 [Term] id: PR:000050788 name: cubilin O-glycosylated 5 (human) def: "A cubilin (human) that has been O-glycosylated at the residue equivalent to Thr-1972 of the amino acid sequence represented by UniProtKB:O60494-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:O60494-1, Thr-1972, MOD:00005~GNO:G43417UB." [GlyGen:O60494-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hCUBN/OGlyco:5" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:O60494-1, Thr-1972, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:O60494 ! cubilin (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000043440 name: cubilin isoform 1 def: "A cubilin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JLB4-1 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "CUBN/iso:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000006043 ! cubilin [Term] id: PR:Q20911 name: cubilin homolog (worm) def: "A cubilin that is encoded in the genome of worm." [OMA:Q20911, PRO:DNx] comment: Category=organism-gene. synonym: "cubn-1" RELATED Gene-based [UniProtKB:Q20911] synonym: "ZC116.3" RELATED Gene-based [UniProtKB:Q20911] synonym: "CUBN (worm)" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q20911 intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans intersection_of: PR:000006043 ! cubilin relationship: has_gene_template WormBase:WBGene00013855 ! cubn-1 (worm) [Term] id: PR:000050782 name: cubilin N-glycosylated 1 (human) def: "A cubilin (human) that has been N-glycosylated at the residue equivalent to Asn-2085 of the amino acid sequence represented by UniProtKB:O60494-1, in which the glycan composition is represented by GlyTouCan:G59334JE. Example: UniProtKB:O60494-1, Asn-2085, MOD:00160~GNO:G59334JE." [GlyGen:O60494-1, PMID:26791533, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hCUBN/NGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:O60494-1, Asn-2085, MOD:00160~GNO:G59334JE" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:O60494 ! cubilin (human) relationship: has_part GNO:G59334JE ! G59334JE relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000050783 name: cubilin N-glycosylated 2 (human) def: "A cubilin (human) that has been N-glycosylated at the residue equivalent to Asn-2531 of the amino acid sequence represented by UniProtKB:O60494-1, in which the glycan composition is represented by GlyTouCan:G00912UN. Example: UniProtKB:O60494-1, Asn-2531, MOD:00160~GNO:G00912UN." [GlyGen:O60494-1, PMID:29671580, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hCUBN/NGlyco:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:O60494-1, Asn-2531, MOD:00160~GNO:G00912UN" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:O60494 ! cubilin (human) relationship: has_part GNO:G00912UN ! G00912UN relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000019581 name: cubilin proteolytic cleavage product def: "A cubilin that has been processed by proteolytic cleavage." [PRO:DNx] comment: Category=modification. synonym: "CUBN/ClvPrd" EXACT PRO-short-label [PRO:DNx] intersection_of: output_of GO:0016485 ! protein processing intersection_of: PR:000006043 ! cubilin [Term] id: PR:Q9JLB4 name: cubilin (mouse) def: "A cubilin that is encoded in the genome of mouse." [OMA:Q9JLB4, PRO:DNx] comment: Category=organism-gene. synonym: "Cubn" RELATED Gene-based [UniProtKB:Q9JLB4] synonym: "Ifcr" RELATED Gene-based [UniProtKB:Q9JLB4] synonym: "mCUBN" EXACT PRO-short-label [PRO:DNx] synonym: "intrinsic factor-cobalamin receptor (mouse)" EXACT [UniProtKB:Q9JLB4] xref: UniProtKB:Q9JLB4 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000006043 ! cubilin relationship: has_gene_template MGI:1931256 ! Cubn (mouse) [Term] id: PR:000050786 name: cubilin O-glycosylated 3 (human) def: "A cubilin (human) that has been O-glycosylated at the residue equivalent to Ser-688 of the amino acid sequence represented by UniProtKB:O60494-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:O60494-1, Ser-688, MOD:00002~GNO:G29068FM." [GlyGen:O60494-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hCUBN/OGlyco:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:O60494-1, Ser-688, MOD:00002~GNO:G29068FM" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:O60494 ! cubilin (human) relationship: has_part GNO:G29068FM ! G29068FM relationship: has_part MOD:00002 ! O-glycosyl-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000050787 name: cubilin O-glycosylated 4 (human) def: "A cubilin (human) that has been O-glycosylated at the residue equivalent to Thr-1972 of the amino acid sequence represented by UniProtKB:O60494-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:O60494-1, Thr-1972, MOD:00005~GNO:G29068FM." [GlyGen:O60494-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hCUBN/OGlyco:4" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:O60494-1, Thr-1972, MOD:00005~GNO:G29068FM" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:O60494 ! cubilin (human) relationship: has_part GNO:G29068FM ! G29068FM relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000050784 name: cubilin O-glycosylated 1 (human) def: "A cubilin (human) that has been O-glycosylated at the residue equivalent to Ser-2904 of the amino acid sequence represented by UniProtKB:O60494-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:O60494-1, Ser-2904, MOD:00002~GNO:G43417UB." [GlyGen:O60494-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hCUBN/OGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:O60494-1, Ser-2904, MOD:00002~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:O60494 ! cubilin (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00002 ! O-glycosyl-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000050785 name: cubilin O-glycosylated 2 (human) def: "A cubilin (human) that has been O-glycosylated at the residue equivalent to Ser-3591 of the amino acid sequence represented by UniProtKB:O60494-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:O60494-1, Ser-3591, MOD:00002~GNO:G43417UB." [GlyGen:O60494-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hCUBN/OGlyco:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:O60494-1, Ser-3591, MOD:00002~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:O60494 ! cubilin (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00002 ! O-glycosyl-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000006043 name: cubilin def: "A protein that is a translation product of the human CUBN gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "CUBN" EXACT PRO-short-label [PRO:DNx] synonym: "IFCR" RELATED Gene-based [] synonym: "460 kDa receptor" EXACT [] synonym: "intrinsic factor-cobalamin receptor" EXACT [] synonym: "intestinal intrinsic factor receptor" EXACT [] synonym: "intrinsic factor-vitamin B12 receptor" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:Q9JLB4-1 name: cubilin isoform 1 (mouse) def: "A cubilin isoform 1 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mCUBN/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9JLB4-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000043440 ! cubilin isoform 1 [Term] id: PR:O70244 name: cubilin (rat) def: "A cubilin that is encoded in the genome of rat." [OMA:O70244, PANTHER:PTHR10127:SF310, PRO:DNx] comment: Category=organism-gene. synonym: "Cubn" RELATED Gene-based [UniProtKB:O70244] synonym: "Ifcr" RELATED Gene-based [UniProtKB:O70244] synonym: "rCUBN" EXACT PRO-short-label [PRO:DNx] synonym: "gp280 (rat)" EXACT [UniProtKB:O70244] synonym: "460 kDa receptor (rat)" EXACT [UniProtKB:O70244] synonym: "glycoprotein 280 (rat)" EXACT [UniProtKB:O70244] synonym: "intrinsic factor-cobalamin receptor (rat)" EXACT [UniProtKB:O70244] synonym: "intrinsic factor-vitamin B12 receptor (rat)" EXACT [UniProtKB:O70244] xref: UniProtKB:O70244 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000006043 ! cubilin relationship: has_gene_template RGD:68355 ! Cubn (rat) [Term] id: PR:Q9W332 name: cubilin homolog (fruit fly) def: "A cubilin that is encoded in the genome of fruit fly." [OMA:Q9W332, PRO:DNx] comment: Category=organism-gene. synonym: "Cubn" RELATED Gene-based [UniProtKB:Q9W332] synonym: "CG32702" RELATED Gene-based [UniProtKB:Q9W332] synonym: "fly-CUBN" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9W332 intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster intersection_of: PR:000006043 ! cubilin relationship: has_gene_template FlyBase:FBgn0052702 ! Cubn (fruit fly) [Term] id: PR:O60494 name: cubilin (human) def: "A cubilin that is encoded in the genome of human." [PRO:DNx, UniProtKB:O60494] comment: Category=organism-gene. synonym: "CUBN" RELATED Gene-based [UniProtKB:O60494] synonym: "IFCR" RELATED Gene-based [UniProtKB:O60494] synonym: "hCUBN" EXACT PRO-short-label [PRO:DNx] synonym: "460 kDa receptor (human)" EXACT [UniProtKB:O60494] synonym: "intrinsic factor-cobalamin receptor (human)" EXACT [UniProtKB:O60494] synonym: "intestinal intrinsic factor receptor (human)" EXACT [UniProtKB:O60494] synonym: "intrinsic factor-vitamin B12 receptor (human)" EXACT [UniProtKB:O60494] xref: UniProtKB:O60494 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000006043 ! cubilin relationship: has_gene_template HGNC:2548 ! CUBN (human)