[Term]
id: PR:P18242
name: cathepsin D (mouse)
def: "A cathepsin D that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-gene.
synonym: "Ctsd" RELATED Gene-based [UniProtKB:P18242]
synonym: "mCTSD" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P18242
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000006025 ! cathepsin D
relationship: has_gene_template MGI:88562 ! Ctsd (mouse)

[Term]
id: PR:000006025
name: cathepsin D
def: "A cathepsin-like protease that is a translation product of the human CTSD gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "CPSD" RELATED Gene-based []
synonym: "CTSD" EXACT PRO-short-label [PRO:DNx]
xref: IUPHARobj:2345
is_a: PR:000040662 ! cathepsin-like protease

[Term]
id: PR:000019561
name: cathepsin D proteolytic cleavage product
def: "A cathepsin D that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "CTSD/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000006025 ! cathepsin D

[Term]
id: PR:000019560
name: cathepsin D, signal peptide removed form
def: "A cathepsin D that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "CTSD/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000006025 ! cathepsin D
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:P07339
name: cathepsin D (human)
def: "A cathepsin D that is encoded in the genome of human." [PRO:DNx, UniProtKB:P07339]
comment: Category=organism-gene.
synonym: "CPSD" RELATED Gene-based [UniProtKB:P07339]
synonym: "CTSD" RELATED Gene-based [UniProtKB:P07339]
synonym: "hCTSD" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P07339
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000006025 ! cathepsin D
relationship: has_gene_template HGNC:2529 ! CTSD (human)

[Term]
id: PR:P24268
name: cathepsin D (rat)
def: "A cathepsin D that is encoded in the genome of rat." [PANTHER:PTHR13683:SF84, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ctsd" RELATED Gene-based [UniProtKB:P24268]
synonym: "rCTSD" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P24268
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000006025 ! cathepsin D
relationship: has_gene_template RGD:621511 ! Ctsd (rat)

[Term]
id: PR:000053727
name: cathepsin D O-glycosylated 1 (human)
def: "A cathepsin D (human) that has been O-glycosylated at the residue equivalent to Thr-63 of the amino acid sequence represented by UniProtKB:P07339-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P07339-1, Thr-63, MOD:00005~GNO:G43417UB." [GlyGen:P07339-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hCTSD/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P07339-1, Thr-63, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P07339 ! cathepsin D (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000058856
name: cathepsin D N-glycosylated 6 (rat)
def: "A cathepsin D (rat) that has been N-glycosylated at the residue equivalent to Asn-258 of the amino acid sequence represented by UniProtKB:P24268-1, in which the glycan composition is represented by GlyTouCan:G41247ZX. Example: UniProtKB:P24268-1, Asn-258, MOD:00160~GNO:G41247ZX." [GlyGen:P24268-1, PMID:24090084, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "rCTSD/NGlyco:6" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P24268-1, Asn-258, MOD:00160~GNO:G41247ZX" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P24268 ! cathepsin D (rat)
relationship: has_part GNO:G41247ZX ! G41247ZX
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000058854
name: cathepsin D N-glycosylated 4 (rat)
def: "A cathepsin D (rat) that has been N-glycosylated at the residue equivalent to Asn-134 of the amino acid sequence represented by UniProtKB:P24268-1, in which the glycan structure is represented by GlyTouCan:G80966KZ. Example: UniProtKB:P24268-1, Asn-134, MOD:00160~GNO:G80966KZ." [GlyGen:P24268-1, PMID:24090084, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "rCTSD/NGlyco:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P24268-1, Asn-134, MOD:00160~GNO:G80966KZ" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P24268-1, Asn-134, MOD:00160~UniCarbKB:1064" NARROW [PRO:DNx]
is_a: PR:P24268 ! cathepsin D (rat)
relationship: has_part GNO:G80966KZ ! G80966KZ
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000058855
name: cathepsin D N-glycosylated 5 (rat)
def: "A cathepsin D (rat) that has been N-glycosylated at the residue equivalent to Asn-258 of the amino acid sequence represented by UniProtKB:P24268-1, in which the glycan composition is represented by GlyTouCan:G02815KT. Example: UniProtKB:P24268-1, Asn-258, MOD:00160~GNO:G02815KT." [GlyGen:P24268-1, PMID:24090084, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "rCTSD/NGlyco:5" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P24268-1, Asn-258, MOD:00160~GNO:G02815KT" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P24268 ! cathepsin D (rat)
relationship: has_part GNO:G02815KT ! G02815KT
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000058852
name: cathepsin D N-glycosylated 2 (rat)
def: "A cathepsin D (rat) that has been N-glycosylated at the residue equivalent to Asn-134 of the amino acid sequence represented by UniProtKB:P24268-1, in which the glycan composition is represented by GlyTouCan:G41247ZX. Example: UniProtKB:P24268-1, Asn-134, MOD:00160~GNO:G41247ZX." [GlyGen:P24268-1, PMID:24090084, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "rCTSD/NGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P24268-1, Asn-134, MOD:00160~GNO:G41247ZX" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P24268 ! cathepsin D (rat)
relationship: has_part GNO:G41247ZX ! G41247ZX
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000058853
name: cathepsin D N-glycosylated 3 (rat)
def: "A cathepsin D (rat) that has been N-glycosylated at the residue equivalent to Asn-134 of the amino acid sequence represented by UniProtKB:P24268-1, in which the glycan structure is represented by GlyTouCan:G55220VL. Example: UniProtKB:P24268-1, Asn-134, MOD:00160~GNO:G55220VL." [GlyGen:P24268-1, PMID:24090084, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "rCTSD/NGlyco:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P24268-1, Asn-134, MOD:00160~GNO:G55220VL" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P24268-1, Asn-134, MOD:00160~UniCarbKB:7666" NARROW [PRO:DNx]
is_a: PR:P24268 ! cathepsin D (rat)
relationship: has_part GNO:G55220VL ! G55220VL
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:Q05744
name: cathepsin D (chicken)
def: "A cathepsin D that is encoded in the genome of chicken." [PANTHER:PTHR13683:SF84, PRO:DNx]
comment: Category=organism-gene.
synonym: "CTSD" RELATED Gene-based [UniProtKB:Q05744]
synonym: "chick-CTSD" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q05744
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000006025 ! cathepsin D
relationship: has_gene_template NCBIGene:396090 ! CTSD (chicken)

[Term]
id: PR:000058851
name: cathepsin D N-glycosylated 1 (rat)
def: "A cathepsin D (rat) that has been N-glycosylated at the residue equivalent to Asn-134 of the amino acid sequence represented by UniProtKB:P24268-1, in which the glycan composition is represented by GlyTouCan:G02815KT. Example: UniProtKB:P24268-1, Asn-134, MOD:00160~GNO:G02815KT." [GlyGen:P24268-1, PMID:24090084, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "rCTSD/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P24268-1, Asn-134, MOD:00160~GNO:G02815KT" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P24268 ! cathepsin D (rat)
relationship: has_part GNO:G02815KT ! G02815KT
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:O76856
name: cathepsin D (Dictyostelium discoideum)
def: "A cathepsin D that is encoded in the genome of Dictyostelium discoideum." [OMA:O76856, PRO:DNx]
comment: Category=organism-gene.
synonym: "CatD" RELATED Gene-based [UniProtKB:O76856]
synonym: "ctsD" RELATED Gene-based [UniProtKB:O76856]
synonym: "Ddp44" EXACT [UniProtKB:O76856]
synonym: "Dicty-CTSD" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0279411" RELATED Gene-based [UniProtKB:O76856]
xref: UniProtKB:O76856
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000006025 ! cathepsin D
relationship: has_gene_template dictyBase:DDB_G0279411 ! ctsD (Dictyostelium discoideum)

[Term]
id: PR:Q21966
name: aspartic protease 4 (worm)
def: "A cathepsin D that is encoded in the genome of worm." [OMA:Q21966, PANTHER:PTHR13683:SF84, PRO:DNx]
comment: Category=organism-gene.
synonym: "asp-4" RELATED Gene-based [UniProtKB:Q21966]
synonym: "R12H7.2" RELATED Gene-based [UniProtKB:Q21966]
synonym: "CTSD (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q21966
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000006025 ! cathepsin D
relationship: has_gene_template WormBase:WBGene00000217 ! asp-4 (worm)

[Term]
id: PR:P32834
name: aspartic proteinase sxa1 (Schizosaccharomyces pombe 972h-)
def: "A cathepsin D that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:P32834, PRO:DNx]
comment: Category=organism-gene.
synonym: "sxa1" RELATED Gene-based [UniProtKB:P32834]
synonym: "SPAC26A3.01" RELATED Gene-based [UniProtKB:P32834]
synonym: "SPAC2E1P5.06" RELATED Gene-based [UniProtKB:P32834]
synonym: "Spom972h-CTSD" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P32834
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000006025 ! cathepsin D
relationship: has_gene_template PomBase:SPAC26A3.01 ! sxa1 (Schizosaccharomyces pombe)