[Term] id: PR:Q9EQH5 name: C-terminal-binding protein 2 (rat) def: "A C-terminal-binding protein 2 that is encoded in the genome of rat." [PANTHER:PTHR10996:SF72, PRO:DAN] comment: Category=organism-gene. synonym: "Ctbp2" RELATED Gene-based [UniProtKB:Q9EQH5] synonym: "rCTBP2" EXACT PRO-short-label [PRO:DNx] synonym: "CtBP2 (rat)" EXACT [UniProtKB:Q9EQH5] xref: UniProtKB:Q9EQH5 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000005995 ! C-terminal-binding protein 2 relationship: has_gene_template RGD:68372 ! Ctbp2 (rat) [Term] id: PR:Q9EQH5-2 name: C-terminal-binding protein 2 isoform 2 (rat) def: "A C-terminal-binding protein 2 isoform 2 that is encoded in the genome of rat." [PRO:DNx] comment: Category=organism-sequence. synonym: "rCTBP2/iso:2" EXACT PRO-short-label [PRO:DNx] synonym: "C-terminal-binding protein 2 isoform Ribeye (rat)" EXACT [UniProtKB:Q9EQH5] xref: UniProtKB:Q9EQH5-2 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000039825 ! C-terminal-binding protein 2 isoform 2 [Term] id: PR:Q9EQH5-1 name: C-terminal-binding protein 2 isoform r1 (rat) def: "A C-terminal-binding protein 2 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9EQH5-1." [PRO:DNx, UniProtKB:Q9EQH5] comment: Category=organism-sequence. synonym: "rCTBP2/iso:r1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q9EQH5-1 is_a: PR:Q9EQH5 ! C-terminal-binding protein 2 (rat) relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus [Term] id: PR:P56546 name: C-terminal-binding protein 2 (mouse) def: "A C-terminal-binding protein 2 that is encoded in the genome of mouse." [OMA:P56546, PRO:DNx] comment: Category=organism-gene. synonym: "Ctbp2" RELATED Gene-based [UniProtKB:P56546] synonym: "mCTBP2" EXACT PRO-short-label [PRO:DNx] synonym: "CtBP2 (mouse)" EXACT [UniProtKB:P56546] xref: UniProtKB:P56546 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000005995 ! C-terminal-binding protein 2 relationship: has_gene_template MGI:1201686 ! Ctbp2 (mouse) [Term] id: PR:P40054 name: D-3-phosphoglycerate dehydrogenase 1 (yeast) def: "A C-terminal-binding protein 2 that is encoded in the genome of yeast." [OMA:P40054, PRO:DNx] comment: Category=organism-gene. synonym: "SER3" RELATED Gene-based [UniProtKB:P40054] synonym: "yCTBP2" EXACT PRO-short-label [PRO:DNx] synonym: "YER081W" RELATED Gene-based [UniProtKB:P40054] synonym: "3-PGDH 1 (yeast)" EXACT [UniProtKB:P40054] synonym: "2-oxoglutarate reductase (yeast)" RELATED [UniProtKB:P40054] xref: UniProtKB:P40054 intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C intersection_of: PR:000005995 ! C-terminal-binding protein 2 relationship: has_gene_template SGD:S000000883 ! SER3 (yeast) [Term] id: PR:000039825 name: C-terminal-binding protein 2 isoform 2 def: "A C-terminal-binding protein 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P56546-2 or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=sequence. synonym: "CTBP2/iso:2" EXACT PRO-short-label [PRO:DNx] is_a: PR:000005995 ! C-terminal-binding protein 2 [Term] id: PR:P56546-1 name: C-terminal-binding protein 2 isoform 1 (mouse) def: "A C-terminal-binding protein 2 isoform 1 that is encoded in the genome of mouse." [PRO:CNA] comment: Category=organism-sequence. synonym: "mCTBP2/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P56546-1 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000028566 ! C-terminal-binding protein 2 isoform 1 [Term] id: PR:000028569 name: C-terminal-binding protein 2 isoform 1 acetylated 1 (human) def: "A C-terminal-binding protein 2 isoform 1 acetylated 1 in human. Acetylation of Lys-10 is critical for nuclear retention and regulation of transcriptional activity of CtBP2 protein. UniProtKB:P56545-1, Lys-6/Lys-8/Lys-10, MOD:00064." [KAT:P56545, PMID:16356938, PRO:PD] comment: Category=organism-modification. Acetylase=("EP300"; PR:000007102). synonym: "hCTBP2/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx] synonym: "CtBP2 acetylated (human)" RELATED [] synonym: "UniProtKB:P56545-1, Lys-6/Lys-8/Lys-10, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000028568 ! C-terminal-binding protein 2 isoform 1 acetylated 1 relationship: has_part MOD:00064 ! N6-acetyl-L-lysine [Term] id: PR:000028568 name: C-terminal-binding protein 2 isoform 1 acetylated 1 def: "A C-terminal-binding protein 2 isoform 1 that is acetylated on the Lys residues in the motif KHKVKR located at the N-terminal region. Example: UniProtKB:P56545-1, Lys-6/Lys-8/Lys-10, MOD:00064." [KAT:P56545, PMID:16356938, PRO:PD] comment: Category=modification. synonym: "CTBP2/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx] synonym: "CtBP2 acetylated" RELATED [] is_a: PR:000028566 ! C-terminal-binding protein 2 isoform 1 relationship: has_part MOD:00064 ! N6-acetyl-L-lysine [Term] id: PR:000005995 name: C-terminal-binding protein 2 def: "A protein that is a translation product of the human CTBP2 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "CTBP2" EXACT PRO-short-label [PRO:DNx] synonym: "CtBP2" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:P56545-2 name: C-terminal-binding protein 2 isoform h2 (human) def: "A C-terminal-binding protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P56545-2." [PRO:DNx, UniProtKB:P56545] comment: Category=organism-sequence. synonym: "hCTBP2/iso:h2" EXACT PRO-short-label [PRO:DNx] synonym: "C-terminal-binding protein 2 isoform Ribeye (human)" EXACT [UniProtKB:P56545] xref: UniProtKB:P56545-2 is_a: PR:P56545 ! C-terminal-binding protein 2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P56545-1 name: C-terminal-binding protein 2 isoform 1 (human) def: "A C-terminal-binding protein 2 isoform 1 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-sequence. synonym: "hCTBP2/iso:1" EXACT PRO-short-label [PRO:DNx] synonym: "CtBP2 isoform 1 (human)" EXACT [] xref: UniProtKB:P56545-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000028566 ! C-terminal-binding protein 2 isoform 1 [Term] id: PR:P56545-3 name: C-terminal-binding protein 2 isoform h3 (human) def: "A C-terminal-binding protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P56545-3." [PRO:DNx, UniProtKB:P56545] comment: Category=organism-sequence. synonym: "hCTBP2/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P56545-3 is_a: PR:P56545 ! C-terminal-binding protein 2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P56545 name: C-terminal-binding protein 2 (human) def: "A C-terminal-binding protein 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P56545] comment: Category=organism-gene. synonym: "CTBP2" RELATED Gene-based [UniProtKB:P56545] synonym: "hCTBP2" EXACT PRO-short-label [PRO:DNx] synonym: "CtBP2 (human)" EXACT [UniProtKB:P56545] xref: Reactome:R-HSA-5333990 "PR:P56545 located_in GO:0005654" xref: UniProtKB:P56545 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000005995 ! C-terminal-binding protein 2 relationship: has_gene_template HGNC:2495 ! CTBP2 (human) [Term] id: PR:P56546-2 name: C-terminal-binding protein 2 isoform 2 (mouse) def: "A C-terminal-binding protein 2 isoform 2 that is encoded in the genome of mouse." [PRO:DNx] comment: Category=organism-sequence. synonym: "mCTBP2/iso:2" EXACT PRO-short-label [PRO:DNx] synonym: "C-terminal-binding protein 2 isoform Ribeye (mouse)" EXACT [UniProtKB:P56546] xref: UniProtKB:P56546-2 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000039825 ! C-terminal-binding protein 2 isoform 2 [Term] id: PR:000028566 name: C-terminal-binding protein 2 isoform 1 def: "A C-terminal-binding protein 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P56545-1 or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=sequence. synonym: "CTBP2/iso:1" EXACT PRO-short-label [PRO:DNx] synonym: "CtBP2 isoform 1" EXACT [] is_a: PR:000005995 ! C-terminal-binding protein 2