[Term]
id: PR:000037262
name: cochlin p18 (mouse)
def: "A cochlin, signal peptide removed form (mouse) that results from cleavage downstream of the LCCL domain (Pfam:PF03815), and includes at least one glycosylated residue. UniProtKB:Q62507, 26-134, MOD:00693." [PMID:23684986, PRO:KRC]
comment: Category=organism-modification.
synonym: "mCOCH/Clv:p18" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:Q62507, 26-134, MOD:00693" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "N-terminal fragment glycosylated (mouse)" EXACT []
is_a: PR:000037260 ! cochlin, signal peptide removed form (mouse)
relationship: output_of GO:0016485 ! protein processing
relationship: has_part MOD:00693 ! glycosylated residue
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000037263
name: cochlin p40 (mouse)
def: "A cochlin, signal peptide removed form (mouse) that results from further cleavage of the LCCL domain (Pfam:PF03815) after aggrecanases proteolytic activity. UniProtKB:Q62507, 135-552." [PMID:23684986, PRO:KRC]
comment: Category=organism-modification.
synonym: "mCOCH/Clv:p40" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:Q62507, 135-552" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "cochlin C-terminal fragment (mouse)" EXACT []
is_a: PR:000037260 ! cochlin, signal peptide removed form (mouse)
relationship: output_of GO:0016485 ! protein processing
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000037260
name: cochlin, signal peptide removed form (mouse)
def: "A cochlin (mouse) that the signal peptide has been removed. UniProtKB:Q62507, 26-552." [PMID:23684986, PRO:KRC]
comment: Category=organism-modification. Evidence=(ECO:0000305, based on UniProtKB:Q62507, PMID:23684986).
synonym: "mCOCH/SigPep-" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:Q62507, 26-552" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: PR:Q62507 ! cochlin (mouse)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000037261
name: cochlin p8 (mouse)
def: "A cochlin, signal peptide removed form (mouse) that results from cleavage downstream of the LCCL domain (Pfam:PF03815) by aggrecanases proteolytic activity. This form results from the deglycosylation of the N-terminal fragment p18. UniProtKB:Q62507, 26-134." [PMID:23684986, PRO:KRC]
comment: Category=organism-modification.
synonym: "mCOCH/Clv:p8" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:Q62507, 26-134" EXACT PRO-proteoform-std [PRO:DNx]
synonym: "N-terminal fragment (mouse)" RELATED []
is_a: PR:000037260 ! cochlin, signal peptide removed form (mouse)
relationship: output_of GO:0016485 ! protein processing
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000037266
name: cochlin N-terminal fragment (mouse)
def: "A cochlin (mouse) that consists of the region upstream of LCCL domain (Pfam:PF03815) without the signal peptide. The fragment may or may not be glycosylated." [PMID:23684986, PRO:KRC]
comment: Category=union.
synonym: "mCOCH/Nter" EXACT PRO-short-label [PRO:DAN]
is_a: PR:Q62507 ! cochlin (mouse)
union_of: PR:000037261 ! cochlin p8 (mouse)
union_of: PR:000037262 ! cochlin p18 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000037264
name: cochlin, signal peptide removed glycosylated form (mouse)
def: "A cochlin, signal peptide removed form (mouse) that includes at least one glycosylated residue. UniProtKB:Q62507, 26-552, MOD:00693." [PMID:23684986, PRO:KRC]
comment: Category=organism-modification. Evidence=(ECO:0000305, based on UniProtKB:Q62507, PMID:23684986).
synonym: "mCOCH/SigPep-/GlycoRes+" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:Q62507, 26-552, MOD:00693" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: has_part MOD:00693 ! glycosylated residue
intersection_of: PR:000037260 ! cochlin, signal peptide removed form (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000037265
name: cochlin precursor (mouse)
def: "A cochlin (mouse) that has not been subject to any proteolytic cleavage. UniProtKB:Q62507, 1-552." [PMID:23684986, PRO:KRC]
comment: Category=organism-modification.
synonym: "mCOCH/precursor" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:Q62507, 1-552" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:Q62507 ! cochlin (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:O43405
name: cochlin (human)
def: "A cochlin that is encoded in the genome of human." [PRO:DNx, UniProtKB:O43405]
comment: Category=organism-gene.
synonym: "COCH" RELATED Gene-based [UniProtKB:O43405]
synonym: "hCOCH" EXACT PRO-short-label [PRO:DNx]
synonym: "COCH5B2" RELATED Gene-based [UniProtKB:O43405]
synonym: "UNQ257/PRO294" RELATED Gene-based [UniProtKB:O43405]
synonym: "COCH-5B2 (human)" EXACT [UniProtKB:O43405]
xref: UniProtKB:O43405
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000005683 ! cochlin
relationship: has_gene_template HGNC:2180 ! COCH (human)

[Term]
id: PR:Q62507
name: cochlin (mouse)
def: "A cochlin that is encoded in the genome of mouse." [OMA:Q62507, PRO:DNx]
comment: Category=organism-gene.
synonym: "Coch" RELATED Gene-based [UniProtKB:Q62507]
synonym: "mCOCH" EXACT PRO-short-label [PRO:DNx]
synonym: "COCH-5B2 (mouse)" EXACT [UniProtKB:Q62507]
xref: UniProtKB:Q62507
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000005683 ! cochlin
relationship: has_gene_template MGI:1278313 ! Coch (mouse)

[Term]
id: PR:000005683
name: cochlin
def: "A protein that is a translation product of the human COCH gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "COCH" EXACT PRO-short-label [PRO:DNx]
synonym: "COCH5B2" RELATED Gene-based []
synonym: "COCH-5B2" EXACT []
synonym: "UNQ257/PRO294" RELATED Gene-based []
is_a: PR:000000001 ! protein

[Term]
id: PR:O42163
name: cochlin (chicken)
def: "A cochlin that is encoded in the genome of chicken." [OMA:O42163, PANTHER:PTHR22992:SF10, PRO:DNx]
comment: Category=organism-gene.
synonym: "COCH" RELATED Gene-based [UniProtKB:O42163]
synonym: "COCH5B2" RELATED Gene-based [UniProtKB:O42163]
synonym: "chick-COCH" EXACT PRO-short-label [PRO:DNx]
synonym: "COCH-5B2 (chicken)" EXACT [UniProtKB:O42163]
xref: UniProtKB:O42163
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000005683 ! cochlin
relationship: has_gene_template NCBIGene:395779 ! COCH (chicken)

[Term]
id: PR:O43405-1
name: cochlin isoform h1 (human)
def: "A cochlin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43405-1." [PRO:DNx, UniProtKB:O43405]
comment: Category=organism-sequence.
synonym: "hCOCH/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O43405-1
is_a: PR:O43405 ! cochlin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000037270
name: cochlin proteolytic cleavage product
def: "A cochlin that has been processed by proteolytic cleavage." [PRO:CNA, PRO:DAN]
comment: Category=modification.
synonym: "COCH/ClvPrd" EXACT PRO-short-label [PRO:DAN]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000005683 ! cochlin

[Term]
id: PR:O43405-2
name: cochlin isoform h2 (human)
def: "A cochlin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O43405-2." [PRO:DNx, UniProtKB:O43405]
comment: Category=organism-sequence.
synonym: "hCOCH/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O43405-2
is_a: PR:O43405 ! cochlin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens