[Term]
id: PR:000046738
name: circadian locomoter output cycles protein kaput phosphoserine form (human)
def: "A circadian locomoter output cycles protein kaput (human) that includes at least one phosphorylated serine. UniProtKB:O15516, MOD:00046." [PRO:DNx, Reactome:R-HSA-421310]
comment: Category=organism-modification.
synonym: "hCLOCK/PhosSer+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O15516, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-421310 "PR:000046738 located_in GO:0005654"
intersection_of: has_part MOD:00046 ! O-phospho-L-serine
intersection_of: PR:O15516 ! circadian locomoter output cycles protein kaput (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000005597
name: circadian locomoter output cycles protein kaput
def: "A protein that is a translation product of the human CLOCK gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "CLOCK" EXACT PRO-short-label [PRO:DNx]
synonym: "BHLHE8" RELATED Gene-based []
synonym: "bHLHe8" EXACT []
synonym: "KIAA0334" RELATED Gene-based []
synonym: "class E basic helix-loop-helix protein 8" EXACT []
xref: IUPHARobj:2649
is_a: PR:000000001 ! protein

[Term]
id: PR:O15516
name: circadian locomoter output cycles protein kaput (human)
def: "A circadian locomoter output cycles protein kaput that is encoded in the genome of human." [PRO:DNx, UniProtKB:O15516]
comment: Category=organism-gene.
synonym: "CLOCK" RELATED Gene-based [UniProtKB:O15516]
synonym: "BHLHE8" RELATED Gene-based [UniProtKB:O15516]
synonym: "hCLOCK" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0334" RELATED Gene-based [UniProtKB:O15516]
synonym: "class E basic helix-loop-helix protein 8 (human)" EXACT [UniProtKB:O15516]
xref: Reactome:R-HSA-400392 "PR:O15516 located_in GO:0005829"
xref: Reactome:R-HSA-879828 "PR:O15516 located_in GO:0005654"
xref: UniProtKB:O15516
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000005597 ! circadian locomoter output cycles protein kaput
relationship: has_gene_template HGNC:2082 ! CLOCK (human)