[Term] id: PR:000046115 name: dual specificity protein kinase CLK2 phosphorylated 1 (mouse) def: "A dual specificity protein kinase CLK2 (mouse) that has been phosphorylated at Ser-141. UniProtKB:O35491, Ser-141, MOD:00046." [PMID:9852100, iPTMnet:O35491] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:9852100). Status=unreviewed. synonym: "mCLK2/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:O35491, Ser-141, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] is_a: PR:O35491 ! dual specificity protein kinase CLK2 (mouse) relationship: has_part MOD:00046 ! O-phospho-L-serine relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus [Term] id: PR:O35491 name: dual specificity protein kinase CLK2 (mouse) def: "A dual specificity protein kinase CLK2 that is encoded in the genome of mouse." [OMA:O35491, PRO:DNx] comment: Category=organism-gene. synonym: "Clk2" RELATED Gene-based [UniProtKB:O35491] synonym: "mCLK2" EXACT PRO-short-label [PRO:DNx] synonym: "CDC-like kinase 2 (mouse)" EXACT [UniProtKB:O35491] xref: UniProtKB:O35491 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000005585 ! dual specificity protein kinase CLK2 relationship: has_gene_template MGI:1098669 ! Clk2 (mouse) [Term] id: PR:P49762-1 name: serine/threonine-protein kinase Doa isoform C (fruit fly) def: "A serine/threonine-protein kinase Doa (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49762-1." [PRO:DNx, UniProtKB:P49762] comment: Category=organism-sequence. synonym: "fly-CLK2/iso:C" EXACT PRO-short-label [PRO:DNx] synonym: "serine/threonine-protein kinase Doa isoform 105 kDa isoform (fruit fly)" EXACT [UniProtKB:P49762] xref: UniProtKB:P49762-1 is_a: PR:P49762 ! serine/threonine-protein kinase Doa (fruit fly) relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster [Term] id: PR:P49762-2 name: serine/threonine-protein kinase Doa isoform A (fruit fly) def: "A serine/threonine-protein kinase Doa (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49762-2." [PRO:DNx, UniProtKB:P49762] comment: Category=organism-sequence. synonym: "fly-CLK2/iso:A" EXACT PRO-short-label [PRO:DNx] synonym: "serine/threonine-protein kinase Doa isoform 55 kDa isoform (fruit fly)" EXACT [UniProtKB:P49762] xref: UniProtKB:P49762-2 is_a: PR:P49762 ! serine/threonine-protein kinase Doa (fruit fly) relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster [Term] id: PR:P49762-3 name: serine/threonine-protein kinase Doa isoform B (fruit fly) def: "A serine/threonine-protein kinase Doa (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49762-3." [PRO:DNx, UniProtKB:P49762] comment: Category=organism-sequence. synonym: "fly-CLK2/iso:B" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P49762-3 is_a: PR:P49762 ! serine/threonine-protein kinase Doa (fruit fly) relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster [Term] id: PR:P49762 name: serine/threonine-protein kinase Doa (fruit fly) def: "A dual specificity protein kinase CLK2 that is encoded in the genome of fruit fly." [PANTHER:PTHR24058:SF33, PRO:DNx] comment: Category=organism-gene. synonym: "Doa" RELATED Gene-based [UniProtKB:P49762] synonym: "CG42320" RELATED Gene-based [UniProtKB:P49762] synonym: "fly-CLK2" EXACT PRO-short-label [PRO:DNx] synonym: "protein darkener of apricot (fruit fly)" EXACT [UniProtKB:P49762] xref: UniProtKB:P49762 intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster intersection_of: PR:000005585 ! dual specificity protein kinase CLK2 relationship: has_gene_template FlyBase:FBgn0265998 ! Doa (fruit fly) [Term] id: PR:P49760 name: dual specificity protein kinase CLK2 (human) def: "A dual specificity protein kinase CLK2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P49760] comment: Category=organism-gene. synonym: "CLK2" RELATED Gene-based [UniProtKB:P49760] synonym: "hCLK2" EXACT PRO-short-label [PRO:DNx] synonym: "CDC-like kinase 2 (human)" EXACT [UniProtKB:P49760] xref: DTO:03100087 xref: UniProtKB:P49760 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000005585 ! dual specificity protein kinase CLK2 relationship: has_gene_template HGNC:2069 ! CLK2 (human) [Term] id: PR:000005585 name: dual specificity protein kinase CLK2 def: "A protein that is a translation product of the human CLK2 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "CLK2" EXACT PRO-short-label [PRO:DNx] synonym: "CDC-like kinase 2" EXACT [] xref: IUPHARobj:1991 is_a: PR:000000001 ! protein [Term] id: PR:P49760-2 name: dual specificity protein kinase CLK2 isoform h2 (human) def: "A dual specificity protein kinase CLK2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49760-2." [PRO:DNx, UniProtKB:P49760] comment: Category=organism-sequence. synonym: "hCLK2/iso:h2" EXACT PRO-short-label [PRO:DNx] synonym: "dual specificity protein kinase CLK2 isoform Short (human)" EXACT [UniProtKB:P49760] xref: UniProtKB:P49760-2 is_a: PR:P49760 ! dual specificity protein kinase CLK2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P49760-3 name: dual specificity protein kinase CLK2 isoform h3 (human) def: "A dual specificity protein kinase CLK2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49760-3." [PRO:DNx, UniProtKB:P49760] comment: Category=organism-sequence. synonym: "hCLK2/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P49760-3 is_a: PR:P49760 ! dual specificity protein kinase CLK2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:P49760-1 name: dual specificity protein kinase CLK2 isoform h1 (human) def: "A dual specificity protein kinase CLK2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49760-1." [PRO:DNx, UniProtKB:P49760] comment: Category=organism-sequence. synonym: "hCLK2/iso:h1" EXACT PRO-short-label [PRO:DNx] synonym: "dual specificity protein kinase CLK2 isoform Long (human)" EXACT [UniProtKB:P49760] xref: UniProtKB:P49760-1 is_a: PR:P49760 ! dual specificity protein kinase CLK2 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens