[Term]
id: PR:000005457
name: neuronal acetylcholine receptor subunit alpha-4
def: "A nicotinic acetylcholine receptor protein that is a translation product of the human CHRNA4 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "Acra4" RELATED Gene-based []
synonym: "CHRNA4" EXACT PRO-short-label [PRO:DNx]
synonym: "NACRA4" RELATED Gene-based []
xref: IUPHARobj:465
is_a: PR:000044668 ! nicotinic acetylcholine receptor protein

[Term]
id: PR:000045362
name: neuronal acetylcholine receptor subunit alpha-4 sequence variant (mouse)
def: "A neuronal acetylcholine receptor subunit alpha-4 (mouse) that has at least one amino acid residue that differs from the corresponding residue found in another neuronal acetylcholine receptor subunit alpha-4 (mouse) when such a difference arises as the result of genetic differences, i.e., different alleles of neuronal acetylcholine receptor subunit alpha-4 (mouse). Operationally, this means the sequence representation of the neuronal acetylcholine receptor subunit alpha-4 (mouse) has at least one amino acid residue that differs from the corresponding residue found of the amino acid sequence represented by UniProtKB:O70174-1." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "mChrna4/var+" EXACT PRO-short-label [PRO:DAN]
is_a: PR:O70174 ! neuronal acetylcholine receptor subunit alpha-4 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000045363
name: neuronal acetylcholine receptor subunit alpha-4 sequence variant T529A (mouse)
def: "A neuronal acetylcholine receptor subunit alpha-4 sequence variant (mouse) that has an Ala residue at the position equivalent to Thr-529 of the amino acid sequence represented by UniProtKB:O70174. UniProtKB:O70174, Thr-529, CHEBI:46217." [PMID:12871652, PRO:HJD]
comment: Category=organism-sequence.
synonym: "mChrna4/var:T529A" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:O70174, Thr-529, CHEBI:46217" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:000045362 ! neuronal acetylcholine receptor subunit alpha-4 sequence variant (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:O70174
name: neuronal acetylcholine receptor subunit alpha-4 (mouse)
def: "A neuronal acetylcholine receptor subunit alpha-4 that is encoded in the genome of mouse." [OMA:O70174, PRO:DNx]
comment: Category=organism-gene.
synonym: "Acra4" RELATED Gene-based [UniProtKB:O70174]
synonym: "Chrna4" RELATED Gene-based [UniProtKB:O70174]
synonym: "mCHRNA4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O70174
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000005457 ! neuronal acetylcholine receptor subunit alpha-4
relationship: has_gene_template MGI:87888 ! Chrna4 (mouse)

[Term]
id: PR:P09483-1
name: neuronal acetylcholine receptor subunit alpha-4 isoform rAlpha-4-1 (rat)
def: "A neuronal acetylcholine receptor subunit alpha-4 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P09483-1." [PRO:DNx, UniProtKB:P09483]
comment: Category=organism-sequence.
synonym: "rCHRNA4/iso:rAlpha-4-1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P09483-1
is_a: PR:P09483 ! neuronal acetylcholine receptor subunit alpha-4 (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:P09483-2
name: neuronal acetylcholine receptor subunit alpha-4 isoform rAlpha-4-2 (rat)
def: "A neuronal acetylcholine receptor subunit alpha-4 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P09483-2." [PRO:DNx, UniProtKB:P09483]
comment: Category=organism-sequence.
synonym: "rCHRNA4/iso:rAlpha-4-2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P09483-2
is_a: PR:P09483 ! neuronal acetylcholine receptor subunit alpha-4 (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000046715
name: neuronal acetylcholine receptor subunit alpha-4, signal peptide removed form (human)
def: "A neuronal acetylcholine receptor subunit alpha-4 (human) that has had the signal peptide removed. UniProtKB:P43681, 29-627." [PRO:DNx, Reactome:R-HSA-507836]
comment: Category=organism-modification.
synonym: "PRO_0000000351" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hCHRNA4/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P43681, 29-627" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-507836 "PR:000046715 located_in GO:0005886"
intersection_of: PR:P43681 ! neuronal acetylcholine receptor subunit alpha-4 (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P43681-2
name: neuronal acetylcholine receptor subunit alpha-4 isoform h2 (human)
def: "A neuronal acetylcholine receptor subunit alpha-4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43681-2." [PRO:DNx, UniProtKB:P43681]
comment: Category=organism-sequence.
synonym: "hCHRNA4/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P43681-2
is_a: PR:P43681 ! neuronal acetylcholine receptor subunit alpha-4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P43681-1
name: neuronal acetylcholine receptor subunit alpha-4 isoform h1 (human)
def: "A neuronal acetylcholine receptor subunit alpha-4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43681-1." [PRO:DNx, UniProtKB:P43681]
comment: Category=organism-sequence.
synonym: "hCHRNA4/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P43681-1
is_a: PR:P43681 ! neuronal acetylcholine receptor subunit alpha-4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P09482
name: neuronal acetylcholine receptor subunit alpha-4 (chicken)
def: "A neuronal acetylcholine receptor subunit alpha-4 that is encoded in the genome of chicken." [PANTHER:PTHR18945:SF84, PRO:DNx]
comment: Category=organism-gene.
synonym: "CHRNA4" RELATED Gene-based [UniProtKB:P09482]
synonym: "chick-CHRNA4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P09482
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000005457 ! neuronal acetylcholine receptor subunit alpha-4
relationship: has_gene_template CGNC:49398 ! CHRNA4 (chicken)

[Term]
id: PR:P09483
name: neuronal acetylcholine receptor subunit alpha-4 (rat)
def: "A neuronal acetylcholine receptor subunit alpha-4 that is encoded in the genome of rat." [PANTHER:PTHR18945:SF84, PRO:DNx]
comment: Category=organism-gene.
synonym: "Acra4" RELATED Gene-based [UniProtKB:P09483]
synonym: "Chrna4" RELATED Gene-based [UniProtKB:P09483]
synonym: "rCHRNA4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P09483
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000005457 ! neuronal acetylcholine receptor subunit alpha-4
relationship: has_gene_template RGD:2346 ! Chrna4 (rat)

[Term]
id: PR:P43681
name: neuronal acetylcholine receptor subunit alpha-4 (human)
def: "A neuronal acetylcholine receptor subunit alpha-4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P43681]
comment: Category=organism-gene.
synonym: "CHRNA4" RELATED Gene-based [UniProtKB:P43681]
synonym: "NACRA4" RELATED Gene-based [UniProtKB:P43681]
synonym: "hCHRNA4" EXACT PRO-short-label [PRO:DNx]
xref: DTO:01100009
xref: UniProtKB:P43681
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000005457 ! neuronal acetylcholine receptor subunit alpha-4
relationship: has_gene_template HGNC:1958 ! CHRNA4 (human)