[Term]
id: PR:000005366
name: cocaine esterase
def: "A protein that is a translation product of the human CES2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ICE" RELATED Gene-based []
synonym: "CE-2" EXACT []
synonym: "CES2" EXACT PRO-short-label [PRO:DNx]
synonym: "carboxylesterase 2" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:O00748
name: cocaine esterase (human)
def: "A cocaine esterase that is encoded in the genome of human." [PRO:DNx, UniProtKB:O00748]
comment: Category=organism-gene.
synonym: "ICE" RELATED Gene-based [UniProtKB:O00748]
synonym: "CES2" RELATED Gene-based [UniProtKB:O00748]
synonym: "hCE-2" EXACT [UniProtKB:O00748]
synonym: "hCES2" EXACT PRO-short-label [PRO:DNx]
synonym: "CE-2 (human)" EXACT [UniProtKB:O00748]
synonym: "carboxylesterase 2 (human)" EXACT [UniProtKB:O00748]
synonym: "methylumbelliferyl-acetate deacetylase 2 (human)" EXACT [UniProtKB:O00748]
xref: UniProtKB:O00748
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000005366 ! cocaine esterase
relationship: has_gene_template HGNC:1864 ! CES2 (human)

[Term]
id: PR:000046691
name: cocaine esterase, signal peptide removed form (human)
def: "A cocaine esterase (human) that has had the signal peptide removed. UniProtKB:O00748, 27-559." [PRO:DNx, Reactome:R-HSA-5693713]
comment: Category=organism-modification.
synonym: "hCES2/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000008572" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:O00748, 27-559" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5693713 "PR:000046691 located_in GO:0005788"
intersection_of: PR:O00748 ! cocaine esterase (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O00748-2
name: cocaine esterase isoform h2 (human)
def: "A cocaine esterase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00748-2." [PRO:DNx, UniProtKB:O00748]
comment: Category=organism-sequence.
synonym: "hCES2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00748-2
is_a: PR:O00748 ! cocaine esterase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O00748-1
name: cocaine esterase isoform h1 (human)
def: "A cocaine esterase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00748-1." [PRO:DNx, UniProtKB:O00748]
comment: Category=organism-sequence.
synonym: "hCES2/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00748-1
is_a: PR:O00748 ! cocaine esterase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O00748-4
name: cocaine esterase isoform h3 (human)
def: "A cocaine esterase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00748-4." [PRO:DNx, UniProtKB:O00748]
comment: Category=organism-sequence.
synonym: "hCES2/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00748-4
is_a: PR:O00748 ! cocaine esterase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O00748-5
name: cocaine esterase isoform h4 (human)
def: "A cocaine esterase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00748-5." [PRO:DNx, UniProtKB:O00748]
comment: Category=organism-sequence.
synonym: "hCES2/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00748-5
is_a: PR:O00748 ! cocaine esterase (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens