[Term]
id: PR:P50750
name: cyclin-dependent kinase 9 (human)
def: "A cyclin-dependent kinase 9 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P50750]
comment: Category=organism-gene.
synonym: "TAK" RELATED Gene-based [UniProtKB:P50750]
synonym: "CDK9" RELATED Gene-based [UniProtKB:P50750]
synonym: "hCDK9" EXACT PRO-short-label [PRO:DNx]
synonym: "CDC2L4" RELATED Gene-based [UniProtKB:P50750]
synonym: "C-2K (human)" EXACT [UniProtKB:P50750]
synonym: "cell division protein kinase 9 (human)" EXACT [UniProtKB:P50750]
synonym: "serine/threonine-protein kinase PITALRE (human)" EXACT [UniProtKB:P50750]
synonym: "cell division cycle 2-like protein kinase 4 (human)" EXACT [UniProtKB:P50750]
synonym: "Tat-associated kinase complex catalytic subunit (human)" EXACT [UniProtKB:P50750]
xref: Reactome:R-HSA-51801 "PR:P50750 located_in GO:0005654"
xref: DTO:03100075
xref: UniProtKB:P50750
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000005267 ! cyclin-dependent kinase 9
relationship: has_gene_template HGNC:1780 ! CDK9 (human)

[Term]
id: PR:000027934
name: cyclin-dependent kinase 9 isoform 1 acetylated 1 (human)
def: "A cyclin-dependent kinase 9 isoform 1 acetylated 1 in human. UniProtKB:P50750-1, Lys-44, MOD:00064." [KAT:P50750, PMID:17452463]
comment: Category=organism-modification. Acetylase=("EP300"; PR:Q09472; Lys-44).
synonym: "CDK9-AcLys44" EXACT []
synonym: "hCDK9/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P50750-1, Lys-44, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027933 ! cyclin-dependent kinase 9 isoform 1 acetylated 1
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine

[Term]
id: PR:000005267
name: cyclin-dependent kinase 9
def: "A CDK2-related kinase that is a translation product of the human CDK9 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "TAK" RELATED Gene-based []
synonym: "C-2K" EXACT []
synonym: "CDK9" EXACT PRO-short-label [PRO:DNx]
synonym: "CDC2L4" RELATED Gene-based []
synonym: "cell division protein kinase 9" EXACT []
synonym: "serine/threonine-protein kinase PITALRE" EXACT []
synonym: "cell division cycle 2-like protein kinase 4" EXACT []
xref: IUPHARobj:1981
is_a: PR:000003270 ! CDK2-related kinase

[Term]
id: PR:000028670
name: cyclin-dependent kinase 9 isoform 1 acetylated 2 (human)
def: "A cyclin-dependent kinase 9 isoform 1 acetylated 2 in human. UniProtKB:P50750-1, Lys-44/Lys-48, MOD:00064." [PMID:18250157, PRO:PD]
comment: Category=organism-modification. Acetylase=("EP300"; PR:000007102). Acetylase=("KAT2A"; PR:000007902). Acetylase=("KAT2B"; PR:000012332).
synonym: "hCDK9/iso:1/Ac:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P50750-1, Lys-44/Lys-48, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000028669 ! cyclin-dependent kinase 9 isoform 1 acetylated 2
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine

[Term]
id: PR:000045815
name: cyclin-dependent kinase 9 phosphorylated 1 (human)
def: "A cyclin-dependent kinase 9 (human) that has been phosphorylated at the position equivalent to Thr-186 of the amino acid sequence represented by UniProtKB:P50750-1. Example: UniProtKB:P50750-1, Thr-186, MOD:00047." [PMID:15965233, PMID:18829461, iPTMnet:P50750]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:15965233, PMID:18829461). Status=unreviewed.
synonym: "hCDK9/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P50750-1, Thr-186, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P50750 ! cyclin-dependent kinase 9 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P50750-1
name: cyclin-dependent kinase 9 isoform 1 (human)
def: "A cyclin-dependent kinase 9 isoform 1 that is encoded in the genome of human." [KAT:P50750]
comment: Category=organism-sequence. Requested by=PubChem.
synonym: "hCDK9/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P50750-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000027931 ! cyclin-dependent kinase 9 isoform 1

[Term]
id: PR:P50750-2
name: cyclin-dependent kinase 9 isoform h2 (human)
def: "A cyclin-dependent kinase 9 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P50750-2." [PRO:DNx, UniProtKB:P50750]
comment: Category=organism-sequence.
synonym: "hCDK9/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P50750-2
is_a: PR:P50750 ! cyclin-dependent kinase 9 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens