[Term]
id: PR:P06242
name: serine/threonine-protein kinase KIN28 (yeast)
def: "A cyclin-dependent kinase 7 that is encoded in the genome of yeast." [OMA:P06242, PRO:DNx]
comment: Category=organism-gene.
synonym: "D2330" RELATED Gene-based [UniProtKB:P06242]
synonym: "KIN28" RELATED Gene-based [UniProtKB:P06242]
synonym: "yCDK7" EXACT PRO-short-label [PRO:DNx]
synonym: "YDL108W" RELATED Gene-based [UniProtKB:P06242]
xref: UniProtKB:P06242
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000005265 ! cyclin-dependent kinase 7
relationship: has_gene_template SGD:S000002266 ! KIN28 (yeast)

[Term]
id: PR:Q12126
name: serine/threonine-protein kinase crk1 (Schizosaccharomyces pombe 972h-)
def: "A cyclin-dependent kinase 7 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:Q12126, PRO:DNx]
comment: Category=organism-gene.
synonym: "crk1" RELATED Gene-based [UniProtKB:Q12126]
synonym: "mcs6" RELATED Gene-based [UniProtKB:Q12126]
synonym: "mop1" RELATED Gene-based [UniProtKB:Q12126]
synonym: "SPBC19F8.07" RELATED Gene-based [UniProtKB:Q12126]
synonym: "Spom972h-CDK7" EXACT PRO-short-label [PRO:DNx]
synonym: "mitotic catastrophe suppressor 6 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:Q12126]
xref: UniProtKB:Q12126
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000005265 ! cyclin-dependent kinase 7
relationship: has_gene_template PomBase:SPBC19F8.07 ! crk1 (Schizosaccharomyces pombe)

[Term]
id: PR:P50613-1
name: cyclin-dependent kinase 7 isoform 1 (human)
def: "A cyclin-dependent kinase 7 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hCDK7/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P50613-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039645 ! cyclin-dependent kinase 7 isoform 1

[Term]
id: PR:P54685
name: cyclin-dependent kinase 7 (Dictyostelium discoideum)
def: "A cyclin-dependent kinase 7 that is encoded in the genome of Dictyostelium discoideum." [OMA:P54685, PANTHER:PTHR24056:SF93, PRO:DNx]
comment: Category=organism-gene.
synonym: "cdcC" RELATED Gene-based [UniProtKB:P54685]
synonym: "cdcD" RELATED Gene-based [UniProtKB:P54685]
synonym: "cdk7" RELATED Gene-based [UniProtKB:P54685]
synonym: "mo15" RELATED Gene-based [UniProtKB:P54685]
synonym: "Dicty-CDK7" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0285417" RELATED Gene-based [UniProtKB:P54685]
synonym: "CAK (Dictyostelium discoideum)" EXACT [UniProtKB:P54685]
synonym: "MO15 homolog (Dictyostelium discoideum)" EXACT [UniProtKB:P54685]
synonym: "CDK-activating kinase (Dictyostelium discoideum)" EXACT [UniProtKB:P54685]
synonym: "cell division protein kinase 7 (Dictyostelium discoideum)" EXACT [UniProtKB:P54685]
xref: UniProtKB:P54685
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000005265 ! cyclin-dependent kinase 7
relationship: has_gene_template dictyBase:DDB_G0285417 ! cdk7 (Dictyostelium discoideum)

[Term]
id: PR:000005265
name: cyclin-dependent kinase 7
def: "A CDK2-related kinase that is a translation product of the human CDK7 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "CAK" RELATED Gene-based []
synonym: "CAK1" BROAD Gene-based [PRO:DNx]
synonym: "CDK7" EXACT PRO-short-label [PRO:DNx]
synonym: "CRK4" EXACT []
synonym: "MO15" RELATED Gene-based []
synonym: "STK1" RELATED Gene-based []
synonym: "Cdkn7" RELATED []
synonym: "Mpk-7" RELATED Gene-based []
synonym: "p39 Mo15" EXACT []
synonym: "CR4 protein kinase" EXACT []
synonym: "39 kDa protein kinase" EXACT []
synonym: "CDK-activating kinase" BROAD [PRO:DNx]
synonym: "protein-tyrosine kinase MPK-7" EXACT []
synonym: "cell division protein kinase 7" EXACT []
synonym: "TFIIH basal transcription factor complex kinase subunit" EXACT []
xref: IUPHARobj:1979
is_a: PR:000003270 ! CDK2-related kinase

[Term]
id: PR:Q03147
name: cyclin-dependent kinase 7 (mouse)
def: "A cyclin-dependent kinase 7 that is encoded in the genome of mouse." [OMA:Q03147, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cak" RELATED Gene-based [UniProtKB:Q03147]
synonym: "Cdk7" RELATED Gene-based [UniProtKB:Q03147]
synonym: "Crk4" RELATED Gene-based [UniProtKB:Q03147]
synonym: "Mo15" RELATED Gene-based [UniProtKB:Q03147]
synonym: "Cdkn7" RELATED Gene-based [UniProtKB:Q03147]
synonym: "Mpk-7" RELATED Gene-based [UniProtKB:Q03147]
synonym: "mCDK7" EXACT PRO-short-label [PRO:DNx]
synonym: "CRK4 (mouse)" EXACT [UniProtKB:Q03147]
synonym: "P39 Mo15 (mouse)" EXACT [UniProtKB:Q03147]
synonym: "CR4 protein kinase (mouse)" EXACT [UniProtKB:Q03147]
synonym: "39 kDa protein kinase (mouse)" EXACT [UniProtKB:Q03147]
synonym: "CDK-activating kinase (mouse)" EXACT [UniProtKB:Q03147]
synonym: "protein-tyrosine kinase MPK-7 (mouse)" EXACT [UniProtKB:Q03147]
synonym: "cell division protein kinase 7 (mouse)" EXACT [UniProtKB:Q03147]
synonym: "TFIIH basal transcription factor complex kinase subunit (mouse)" EXACT [UniProtKB:Q03147]
xref: UniProtKB:Q03147
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000005265 ! cyclin-dependent kinase 7
relationship: has_gene_template MGI:102956 ! Cdk7 (mouse)

[Term]
id: PR:000045814
name: cyclin-dependent kinase 7 phosphorylated 1 (human)
def: "A cyclin-dependent kinase 7 (human) that has been phosphorylated at Thr-170. UniProtKB:P50613, Thr-170, MOD:00047." [PMID:22021906, iPTMnet:P50613]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:22021906). Status=unreviewed.
synonym: "hCDK7/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P50613, Thr-170, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P50613 ! cyclin-dependent kinase 7 (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q03147-1
name: cyclin-dependent kinase 7 isoform 1 (mouse)
def: "A cyclin-dependent kinase 7 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mCDK7/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q03147-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039645 ! cyclin-dependent kinase 7 isoform 1

[Term]
id: PR:P50613
name: cyclin-dependent kinase 7 (human)
def: "A cyclin-dependent kinase 7 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-gene.
synonym: "CAK" RELATED Gene-based [UniProtKB:P50613]
synonym: "CAK1" RELATED Gene-based [UniProtKB:P50613]
synonym: "CDK7" RELATED Gene-based [UniProtKB:P50613]
synonym: "MO15" RELATED Gene-based [UniProtKB:P50613]
synonym: "STK1" RELATED Gene-based [UniProtKB:P50613]
synonym: "CDKN7" RELATED Gene-based [UniProtKB:P50613]
synonym: "hCDK7" EXACT PRO-short-label [PRO:DNx]
synonym: "p39 Mo15 (human)" EXACT [UniProtKB:P50613]
synonym: "39 kDa protein kinase (human)" EXACT [UniProtKB:P50613]
synonym: "CDK-activating kinase 1 (human)" EXACT [UniProtKB:P50613]
synonym: "cell division protein kinase 7 (human)" EXACT [PRO:DNx]
synonym: "serine/threonine-protein kinase 1 (human)" EXACT [UniProtKB:P50613]
synonym: "TFIIH basal transcription factor complex kinase subunit (human)" EXACT [UniProtKB:P50613]
xref: Reactome:R-HSA-69218 "PR:P50613 located_in GO:0005654"
xref: DTO:03100073
xref: UniProtKB:P50613
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000005265 ! cyclin-dependent kinase 7
relationship: has_gene_template HGNC:1778 ! CDK7 (human)

[Term]
id: PR:G5EFV5
name: cyclin-dependent kinase 7 (worm)
def: "A cyclin-dependent kinase 7 that is encoded in the genome of worm." [OMA:G5EFV5, PRO:DNx]
comment: Category=organism-gene.
synonym: "cdk-7" RELATED Gene-based [UniProtKB:G5EFV5]
synonym: "Y39G10AL.3" RELATED Gene-based [UniProtKB:G5EFV5]
synonym: "CDK7 (worm)" EXACT PRO-short-label [PRO:DNx]
synonym: "cell division protein kinase 7 (worm)" EXACT [UniProtKB:G5EFV5]
xref: UniProtKB:G5EFV5
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000005265 ! cyclin-dependent kinase 7
relationship: has_gene_template WormBase:WBGene00000408 ! cdk-7 (worm)

[Term]
id: PR:000046126
name: serine/threonine-protein kinase KIN28 phosphorylated 1 (yeast)
def: "A serine/threonine-protein kinase KIN28 (yeast) that has been phosphorylated at Thr-162. UniProtKB:P06242, Thr-162, MOD:00047." [PMID:10373527, iPTMnet:P06242]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:10373527). Status=unreviewed.
synonym: "yCDK7/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P06242, Thr-162, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P06242 ! serine/threonine-protein kinase KIN28 (yeast)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C

[Term]
id: PR:000039645
name: cyclin-dependent kinase 7 isoform 1
def: "A cyclin-dependent kinase 7 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P50613-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "CDK7/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000005265 ! cyclin-dependent kinase 7