[Term]
id: PR:000039592
name: cysteine--tRNA ligase, cytoplasmic isoform 3
def: "A cysteine--tRNA ligase, cytoplasmic that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49589-3 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "CARS/iso:3" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000005045 ! cysteine--tRNA ligase, cytoplasmic

[Term]
id: PR:000039591
name: cysteine--tRNA ligase, cytoplasmic isoform 1
def: "A cysteine--tRNA ligase, cytoplasmic that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49589-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "CARS/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000005045 ! cysteine--tRNA ligase, cytoplasmic

[Term]
id: PR:Q09860
name: probable cysteine--tRNA ligase (Schizosaccharomyces pombe 972h-)
def: "A cysteine--tRNA ligase, cytoplasmic that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:Q09860, PRO:DNx]
comment: Category=organism-gene.
synonym: "SPAC29E6.06c" RELATED Gene-based [UniProtKB:Q09860]
synonym: "Spom972h-CARS" EXACT PRO-short-label [PRO:DNx]
synonym: "CysRS (Schizosaccharomyces pombe 972h-)" BROAD [PRO:DAN, UniProtKB:Q09860]
synonym: "cysteinyl-tRNA synthetase (Schizosaccharomyces pombe 972h-)" BROAD [PRO:DAN, UniProtKB:Q09860]
xref: UniProtKB:Q09860
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000005045 ! cysteine--tRNA ligase, cytoplasmic
relationship: has_gene_template PomBase:SPAC29E6.06c ! SPAC29E6.06c (Schizosaccharomyces pombe)

[Term]
id: PR:Q9ER72-1
name: cysteine--tRNA ligase, cytoplasmic isoform 1 (mouse)
def: "A cysteine--tRNA ligase, cytoplasmic isoform 3 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mCARS/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9ER72-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039592 ! cysteine--tRNA ligase, cytoplasmic isoform 3

[Term]
id: PR:Q9ER72-2
name: cysteine--tRNA ligase, cytoplasmic isoform 2 (mouse)
def: "A cysteine--tRNA ligase, cytoplasmic isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mCARS/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9ER72-2
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039591 ! cysteine--tRNA ligase, cytoplasmic isoform 1

[Term]
id: PR:Q5F408
name: cysteine--tRNA ligase, cytoplasmic (chicken)
def: "A cysteine--tRNA ligase, cytoplasmic that is encoded in the genome of chicken." [OMA:Q5F408, PRO:DNx]
comment: Category=organism-gene.
synonym: "CARS" RELATED Gene-based [UniProtKB:Q5F408]
synonym: "CARS1" RELATED Gene-based [UniProtKB:Q5F408]
synonym: "chick-CARS" EXACT PRO-short-label [PRO:DNx]
synonym: "RCJMB04_3o5" RELATED Gene-based [UniProtKB:Q5F408]
synonym: "CysRS (chicken)" BROAD [PRO:DAN, UniProtKB:Q5F408]
synonym: "cysteine--tRNA ligase (chicken)" BROAD [PRO:DAN]
synonym: "cysteinyl-tRNA synthetase (chicken)" BROAD [PRO:DAN, UniProtKB:Q5F408]
synonym: "cysteinyl-tRNA synthetase, cytoplasmic (chicken)" EXACT [PRO:DAN]
xref: UniProtKB:Q5F408
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000005045 ! cysteine--tRNA ligase, cytoplasmic
relationship: has_gene_template NCBIGene:423086 ! CARS (chicken)

[Term]
id: PR:P49589
name: cysteine--tRNA ligase, cytoplasmic (human)
def: "A cysteine--tRNA ligase, cytoplasmic that is encoded in the genome of human." [PRO:DNx, UniProtKB:P49589]
comment: Category=organism-gene.
synonym: "CARS" RELATED Gene-based [UniProtKB:P49589]
synonym: "CARS1" RELATED Gene-based [UniProtKB:P49589]
synonym: "hCARS" EXACT PRO-short-label [PRO:DNx]
synonym: "CysRS (human)" BROAD [UniProtKB:P49589]
synonym: "cysteinylRS (human)" BROAD [PRO:DAN]
synonym: "cysteine--tRNA ligase (human)" BROAD [PRO:DAN]
synonym: "cysteinyl-tRNA synthetase (human)" BROAD [PRO:DAN]
synonym: "cysteinyl-tRNA synthetase, cytoplasmic (human)" EXACT [PRO:DAN]
xref: Reactome:R-HSA-379602 "PR:P49589 located_in GO:0005829"
xref: UniProtKB:P49589
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000005045 ! cysteine--tRNA ligase, cytoplasmic
relationship: has_gene_template HGNC:1493 ! CARS (human)

[Term]
id: PR:Q54KR1
name: cysteine--tRNA ligase, cytoplasmic (Dictyostelium discoideum)
def: "A cysteine--tRNA ligase, cytoplasmic that is encoded in the genome of Dictyostelium discoideum." [OMA:Q54KR1, PRO:DNx]
comment: Category=organism-gene.
synonym: "cysS" RELATED Gene-based [UniProtKB:Q54KR1]
synonym: "Dicty-CARS" EXACT PRO-short-label [PRO:DNx]
synonym: "DDB_G0287159" RELATED Gene-based [UniProtKB:Q54KR1]
synonym: "CysRS (Dictyostelium discoideum)" BROAD [PRO:DAN, UniProtKB:Q54KR1]
synonym: "cysteine--tRNA ligase (Dictyostelium discoideum)" BROAD [PRO:DAN]
synonym: "cysteinyl-tRNA synthetase (Dictyostelium discoideum)" BROAD [PRO:DAN, UniProtKB:Q54KR1]
synonym: "cysteinyl-tRNA synthetase, cytoplasmic (Dictyostelium discoideum)" EXACT [PRO:DAN]
xref: UniProtKB:Q54KR1
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000005045 ! cysteine--tRNA ligase, cytoplasmic
relationship: has_gene_template dictyBase:DDB_G0287159 ! cysS (Dictyostelium discoideum)

[Term]
id: PR:P49589-3
name: cysteine--tRNA ligase, cytoplasmic isoform 3 (human)
def: "A cysteine--tRNA ligase, cytoplasmic isoform 3 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hCARS/iso:3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P49589-3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039592 ! cysteine--tRNA ligase, cytoplasmic isoform 3

[Term]
id: PR:P49589-2
name: cysteine--tRNA ligase, cytoplasmic isoform h2 (human)
def: "A cysteine--tRNA ligase, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49589-2." [PRO:DNx, UniProtKB:P49589]
comment: Category=organism-sequence.
synonym: "hCARS/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P49589-2
is_a: PR:P49589 ! cysteine--tRNA ligase, cytoplasmic (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P49589-1
name: cysteine--tRNA ligase, cytoplasmic isoform 1 (human)
def: "A cysteine--tRNA ligase, cytoplasmic isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hCARS/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P49589-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039591 ! cysteine--tRNA ligase, cytoplasmic isoform 1

[Term]
id: PR:000049898
name: cysteine--tRNA ligase, cytoplasmic phosphorylated 3 (mouse)
def: "A cysteine--tRNA ligase, cytoplasmic (mouse) that has been phosphorylated at the position equivalent to Ser-390 of the amino acid sequence represented by UniProtKB:Q9ER72-1. Example: UniProtKB:Q9ER72-1, Ser-390, MOD:00046." [PMID:21183079, PRO:HJD]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:21183079).
synonym: "mCARS/Phos:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9ER72-1, Ser-390, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9ER72 ! cysteine--tRNA ligase, cytoplasmic (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9ER72
name: cysteine--tRNA ligase, cytoplasmic (mouse)
def: "A cysteine--tRNA ligase, cytoplasmic that is encoded in the genome of mouse." [OMA:Q9ER72, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cars" RELATED Gene-based [UniProtKB:Q9ER72]
synonym: "Cars1" RELATED Gene-based [UniProtKB:Q9ER72]
synonym: "mCARS" EXACT PRO-short-label [PRO:DNx]
synonym: "CysRS (mouse)" BROAD [PRO:DAN, UniProtKB:Q9ER72]
synonym: "cysteine--tRNA ligase (mouse)" BROAD [PRO:DAN]
synonym: "cysteinyl-tRNA synthetase (mouse)" BROAD [PRO:DAN, UniProtKB:Q9ER72]
synonym: "cysteinyl-tRNA synthetase, cytoplasmic (mouse)" EXACT [PRO:DAN]
xref: UniProtKB:Q9ER72
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000005045 ! cysteine--tRNA ligase, cytoplasmic
relationship: has_gene_template MGI:1351477 ! Cars (mouse)

[Term]
id: PR:000005045
name: cysteine--tRNA ligase, cytoplasmic
def: "A protein that is a translation product of the human CARS gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "CARS" EXACT PRO-short-label [PRO:DNx]
synonym: "CARS1" RELATED Gene-based []
synonym: "CysRS" BROAD [PRO:DAN]
synonym: "cysteine--tRNA ligase" BROAD [PRO:DAN]
synonym: "cysteinyl-tRNA synthetase" BROAD [PRO:DAN]
synonym: "cysteinyl-tRNA synthetase, cytoplasmic" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q5F408-1
name: cysteine--tRNA ligase, cytoplasmic isoform 1 (chicken)
def: "A cysteine--tRNA ligase, cytoplasmic isoform 1 that is encoded in the genome of chicken." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "chick-CARS/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q5F408-1
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000039591 ! cysteine--tRNA ligase, cytoplasmic isoform 1

[Term]
id: PR:P53852
name: cysteine--tRNA ligase (yeast)
def: "A cysteine--tRNA ligase, cytoplasmic that is encoded in the genome of yeast." [OMA:P53852, PRO:DNx]
comment: Category=organism-gene.
synonym: "yCARS" EXACT PRO-short-label [PRO:DNx]
synonym: "YNL247W" RELATED Gene-based [UniProtKB:P53852]
synonym: "CysRS (yeast)" BROAD [PRO:DAN, UniProtKB:P53852]
synonym: "cysteinyl-tRNA synthetase (yeast)" BROAD [PRO:DAN, UniProtKB:P53852]
xref: UniProtKB:P53852
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000005045 ! cysteine--tRNA ligase, cytoplasmic
relationship: has_gene_template SGD:S000005191 ! YNL247W (yeast)

[Term]
id: PR:000049896
name: cysteine--tRNA ligase, cytoplasmic phosphorylated 1 (mouse)
def: "A cysteine--tRNA ligase, cytoplasmic (mouse) that has been phosphorylated at the position equivalent to Ser-102 of the amino acid sequence represented by UniProtKB:Q9ER72-1. Example: UniProtKB:Q9ER72-1, Ser-102, MOD:00046." [PMID:21183079, PRO:HJD]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:21183079).
synonym: "mCARS/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9ER72-1, Ser-102, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9ER72 ! cysteine--tRNA ligase, cytoplasmic (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049897
name: cysteine--tRNA ligase, cytoplasmic phosphorylated 2 (mouse)
def: "A cysteine--tRNA ligase, cytoplasmic (mouse) that has been phosphorylated at the position equivalent to Ser-117 of the amino acid sequence represented by UniProtKB:Q9ER72-1. Example: UniProtKB:Q9ER72-1, Ser-117, MOD:00046." [PMID:21183079, PRO:HJD]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:21183079).
synonym: "mCARS/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9ER72-1, Ser-117, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9ER72 ! cysteine--tRNA ligase, cytoplasmic (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q7KN90
name: cysteine--tRNA ligase, cytoplasmic (fruit fly)
def: "A cysteine--tRNA ligase, cytoplasmic that is encoded in the genome of fruit fly." [OMA:Q7KN90, PRO:DNx]
comment: Category=organism-gene.
synonym: "CysRS" RELATED Gene-based [UniProtKB:Q7KN90]
synonym: "CG8431" RELATED Gene-based [UniProtKB:Q7KN90]
synonym: "Aats-cys" RELATED Gene-based [UniProtKB:Q7KN90]
synonym: "fly-CARS" EXACT PRO-short-label [PRO:DNx]
synonym: "cysteinylRS (fruit fly)" BROAD [PRO:DAN]
synonym: "cysteine--tRNA ligase (fruit fly)" BROAD [PRO:DAN]
synonym: "cysteinyl-tRNA synthetase (fruit fly)" BROAD [PRO:DAN, UniProtKB:Q7KN90]
synonym: "cysteinyl-tRNA synthetase, cytoplasmic (fruit fly)" EXACT [PRO:DAN]
xref: UniProtKB:Q7KN90
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000005045 ! cysteine--tRNA ligase, cytoplasmic
relationship: has_gene_template FlyBase:FBgn0027091 ! CysRS (Drosophila melanogaster)