[Term]
id: PR:000046561
name: calnexin, signal peptide removed form (human)
def: "A calnexin (human) that has had the signal peptide removed. UniProtKB:P27824, 21-592." [PRO:DNx, Reactome:R-HSA-195906, Reactome:R-HSA-983091]
comment: Category=organism-modification.
synonym: "hCANX/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000004198" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P27824, 21-592" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-195906 "PR:000046561 located_in GO:0005788"
xref: Reactome:R-HSA-983091 "PR:000046561 located_in GO:0071556"
intersection_of: PR:P27824 ! calnexin (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000056316
name: calnexin O-glycosylated 3 (human)
def: "A calnexin (human) that has been O-glycosylated at the residue equivalent to Thr-66 of the amino acid sequence represented by UniProtKB:P27824-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P27824-1, Thr-66, MOD:00005~GNO:G43417UB." [GlyGen:P27824-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hCANX/OGlyco:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P27824-1, Thr-66, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P27824 ! calnexin (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000056315
name: calnexin O-glycosylated 2 (human)
def: "A calnexin (human) that has been O-glycosylated at the residue equivalent to Thr-50 of the amino acid sequence represented by UniProtKB:P27824-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P27824-1, Thr-50, MOD:00005~GNO:G43417UB." [GlyGen:P27824-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hCANX/OGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P27824-1, Thr-50, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P27824 ! calnexin (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000056314
name: calnexin O-glycosylated 1 (human)
def: "A calnexin (human) that has been O-glycosylated at the residue equivalent to Thr-49 of the amino acid sequence represented by UniProtKB:P27824-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P27824-1, Thr-49, MOD:00005~GNO:G29068FM." [GlyGen:P27824-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hCANX/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P27824-1, Thr-49, MOD:00005~GNO:G29068FM" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P27824 ! calnexin (human)
relationship: has_part GNO:G29068FM ! G29068FM
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P27824-1
name: calnexin isoform h1 (human)
def: "A calnexin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27824-1." [PRO:DNx, UniProtKB:P27824]
comment: Category=organism-sequence.
synonym: "hCANX/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P27824-1
is_a: PR:P27824 ! calnexin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P27824-3
name: calnexin isoform h3 (human)
def: "A calnexin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27824-3." [PRO:DNx, UniProtKB:P27824]
comment: Category=organism-sequence.
synonym: "hCANX/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P27824-3
is_a: PR:P27824 ! calnexin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P27824-2
name: calnexin isoform h2 (human)
def: "A calnexin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27824-2." [PRO:DNx, UniProtKB:P27824]
comment: Category=organism-sequence.
synonym: "hCANX/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P27824-2
is_a: PR:P27824 ! calnexin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P27824
name: calnexin (human)
def: "A calnexin that is encoded in the genome of human." [PRO:DNx, UniProtKB:P27824]
comment: Category=organism-gene.
synonym: "CANX" RELATED Gene-based [UniProtKB:P27824]
synonym: "hCANX" EXACT PRO-short-label [PRO:DNx]
synonym: "p90 (human)" BROAD [UniProtKB:P27824]
synonym: "IP90 (human)" EXACT [UniProtKB:P27824]
synonym: "major histocompatibility complex class I antigen-binding protein p88 (human)" EXACT [UniProtKB:P27824]
xref: UniProtKB:P27824
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000005005 ! calnexin
relationship: has_gene_template HGNC:1473 ! CANX (human)

[Term]
id: PR:000005005
name: calnexin
def: "A protein that is a translation product of the human CANX gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "p90" BROAD [PRO:DNx]
synonym: "CANX" EXACT PRO-short-label [PRO:DNx]
synonym: "IP90" EXACT []
synonym: "major histocompatibility complex class I antigen-binding protein p88" EXACT []
is_a: PR:000000001 ! protein