[Term]
id: PR:Q09794
name: protein ura1 (Schizosaccharomyces pombe 972h-)
def: "A CAD protein that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PRO:DAN]
comment: Category=organism-gene.
synonym: "ura1" RELATED Gene-based [UniProtKB:Q09794]
synonym: "SPAC22G7.06c" RELATED Gene-based [UniProtKB:Q09794]
synonym: "Spom972h-CAD" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q09794
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000004959 ! CAD protein
relationship: has_gene_template PomBase:SPAC22G7.06c ! ura1 (Schizosaccharomyces pombe)

[Term]
id: PR:000046548
name: CAD protein, initiator methionine removed form (human)
def: "A CAD protein (human) that has had the initiator methionine removed. UniProtKB:P27708, 2-2225." [PRO:DNx, Reactome:R-HSA-73452]
comment: Category=organism-modification.
synonym: "hCAD/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000199506" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P27708, 2-2225" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-73452 "PR:000046548 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P27708 ! CAD protein (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P07259
name: protein URA2 (yeast)
def: "A CAD protein that is encoded in the genome of yeast." [PRO:DAN]
comment: Category=organism-gene.
synonym: "URA2" RELATED Gene-based [UniProtKB:P07259]
synonym: "yCAD" EXACT PRO-short-label [PRO:DNx]
synonym: "J0686" RELATED Gene-based [UniProtKB:P07259]
synonym: "YJL130C" RELATED Gene-based [UniProtKB:P07259]
xref: UniProtKB:P07259
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000004959 ! CAD protein
relationship: has_gene_template SGD:S000003666 ! URA2 (yeast)

[Term]
id: PR:000004959
name: CAD protein
def: "A protein that is a translation product of the human CAD gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "CAD" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000039178
name: CAD protein isoform 1
def: "A CAD protein that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P27708-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "CAD/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000004959 ! CAD protein

[Term]
id: PR:B2RQC6
name: CAD protein (mouse)
def: "A CAD protein that is encoded in the genome of mouse." [OMA:B2RQC6, PRO:DNx]
comment: Category=organism-gene.
synonym: "Cad" RELATED Gene-based [UniProtKB:B2RQC6]
synonym: "mCAD" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:B2RQC6
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000004959 ! CAD protein
relationship: has_gene_template MGI:1916969 ! Cad (mouse)

[Term]
id: PR:Q18990
name: CAD protein (worm)
def: "A CAD protein that is encoded in the genome of worm." [OMA:Q18990, PRO:DAN]
comment: Category=organism-gene.
synonym: "pyr-1" RELATED Gene-based [UniProtKB:Q18990]
synonym: "D2085.1" RELATED Gene-based [UniProtKB:Q18990]
synonym: "CAD (worm)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q18990
intersection_of: only_in_taxon NCBITaxon:6239 ! Caenorhabditis elegans
intersection_of: PR:000004959 ! CAD protein
relationship: has_gene_template WormBase:WBGene00004259 ! pyr-1 (worm)

[Term]
id: PR:P27708
name: CAD protein (human)
def: "A CAD protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:P27708]
comment: Category=organism-gene.
synonym: "CAD" RELATED Gene-based [UniProtKB:P27708]
synonym: "hCAD" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P27708
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004959 ! CAD protein
relationship: has_gene_template HGNC:1424 ! CAD (human)

[Term]
id: PR:P27708-1
name: CAD protein isoform 1 (human)
def: "A CAD protein isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hCAD/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P27708-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000039178 ! CAD protein isoform 1

[Term]
id: PR:000019217
name: CAD protein, initiator methionine removed form
def: "A CAD protein that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "CAD/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000004959 ! CAD protein
intersection_of: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:B2RQC6-1
name: CAD protein isoform 1 (mouse)
def: "A CAD protein isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mCAD/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:B2RQC6-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000039178 ! CAD protein isoform 1

[Term]
id: PR:B2RQC6-2
name: CAD protein isoform m2 (mouse)
def: "A CAD protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:B2RQC6-2." [PRO:DNx, UniProtKB:B2RQC6]
comment: Category=organism-sequence.
synonym: "mCAD/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:B2RQC6-2
is_a: PR:B2RQC6 ! CAD protein (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P05990
name: CAD protein (fruit fly)
def: "A CAD protein that is encoded in the genome of fruit fly." [OMA:P05990, PRO:DAN]
comment: Category=organism-gene.
synonym: "r" RELATED Gene-based [UniProtKB:P05990]
synonym: "CG18572" RELATED Gene-based [UniProtKB:P05990]
synonym: "fly-CAD" EXACT PRO-short-label [PRO:DNx]
synonym: "protein rudimentary (fruit fly)" EXACT [UniProtKB:P05990]
xref: UniProtKB:P05990
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000004959 ! CAD protein
relationship: has_gene_template FlyBase:FBgn0003189 ! r (fruit fly)

[Term]
id: PR:000045732
name: CAD protein phosphorylated 1 (human)
def: "A CAD protein (human) that has been phosphorylated at Thr-456. UniProtKB:P27708, Thr-456, MOD:00047." [PMID:15890648, iPTMnet:P27708]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:15890648). Status=unreviewed.
synonym: "hCAD/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P27708, Thr-456, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P27708 ! CAD protein (human)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens