[Term]
id: PR:000004912
name: vertebrate-type carbonic anhydrase 1
def: "A single domain alpha-type carbonic anhydrase that is a translation product of the human CA1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "CA1" EXACT PRO-short-label [PRO:DNx]
synonym: "CAB" RELATED []
synonym: "CA-I" EXACT []
synonym: "Car1" RELATED Gene-based []
synonym: "carbonic anhydrase B" EXACT []
synonym: "carbonic anhydrase I" EXACT []
synonym: "carbonate dehydratase I" EXACT []
xref: IUPHARobj:2597
is_a: PR:000025841 ! single domain alpha-type carbonic anhydrase

[Term]
id: PR:000046537
name: carbonic anhydrase 1, initiator methionine removed form (human)
def: "A carbonic anhydrase 1 (human) that has had the initiator methionine removed. UniProtKB:P00915, 2-261." [PRO:DNx, Reactome:R-HSA-1237027]
comment: Category=organism-modification.
synonym: "hCA1/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000077409" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P00915, 2-261" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1237027 "PR:000046537 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P00915 ! carbonic anhydrase 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P00915-1
name: carbonic anhydrase 1 isoform 1 (human)
def: "A vertebrate-type carbonic anhydrase 1 isoform 1 that is encoded in the genome of human." [PMID:17968930, SALO:AJ]
comment: Category=organism-sequence. Salivary Sjogren's syndrome biomarker.
synonym: "hCA1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P00915-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000025656 ! vertebrate-type carbonic anhydrase 1 isoform 1

[Term]
id: PR:P00915
name: carbonic anhydrase 1 (human)
def: "A vertebrate-type carbonic anhydrase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P00915]
comment: Category=organism-gene.
synonym: "CA1" RELATED Gene-based [UniProtKB:P00915]
synonym: "hCA1" EXACT PRO-short-label [PRO:DNx]
synonym: "CAB (human)" BROAD [UniProtKB:P00915]
synonym: "CA-I (human)" EXACT [UniProtKB:P00915]
synonym: "carbonic anhydrase B (human)" EXACT [UniProtKB:P00915]
synonym: "carbonic anhydrase I (human)" EXACT [UniProtKB:P00915]
synonym: "carbonate dehydratase I (human)" EXACT [UniProtKB:P00915]
xref: UniProtKB:P00915
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000004912 ! vertebrate-type carbonic anhydrase 1
relationship: has_gene_template HGNC:1368 ! CA1 (human)